This student report is about canine atopic dermatitis It includes a description of the immunologic mechanisms and how the reaction affects the body. The symptoms are various, most common is pruritus, erythema and alopecia and directly associated with the immunologic reaction. The diagnostic process includes symptoms, physical findings, differential diagnosis, intradermal test and serological test. The options of treatment are several and vary for each patient. The report includes hyposensitization, medical treatment such as corticosteroids, antihistamin and cyclosporine, topical treatment, fatty acid supplements and environmental treatment. The prognosis is individual for each patient due to their different response to the treatment. It may take a while to find the right combination of treatments to achieve satisfactory control of the disease..

Elakartad katarralfeber är en dödlig sjukdom hos nötkreatur som orsakas av herpesvirus från får eller gnuer. I områden där båda virusvarianterna finns kan man skilja dem åt genom PCR-metoder. Sjukdomen verkar bero på en virusorsakad obalans i immunförsvaret och karaktäriseras av infiltration och ansamling av CD8+ T-lymfocyter. Infekterade celler kan omvandlas till ?large granular lymphocytes? som orsakar celldöd i flera olika vävnader.

There are about 700 000 dogs in Sweden. Roughly 70 % of the dogs are purebred and registered in the database at the Swedish Kennel Club (SKC). The database includes records of birth date, pedigree, offspring and results from e.g. veterinary examinations related to genetic health programs.Every year approximately 10% of the dogs die; most are euthanized by a veterinarian. Dog mortality data is stored as digital medical records at animal clinics and in insurance databases.Dog owners tend to register their puppy in the SKC, but they rarely report that the dog has passed away.

This student report is about canine infectious skin diseases. It is primarily directed at veterinary assistans. The report includes a description of the skin?s structure and immunologic defences. The four types of allergic reactions are described. Different diagnostic techniques are also accounted for. The skin diseases included in the report are: fleas, lice, Sarcoptes scabiei, ringworm, Cheyletiella and leishmaniosis.

India is the country with the highest prevalence of rabies in the world, with about 20?000 human deaths occurring every year. The country also has a heavy burden of free roaming dogs, mainly because of the high amount of edible waste in the streets, which are the main hosts for the disease. Therefore to truly extinguish rabies, the main focus should be on the dogs, both stray dogs and owned. One method is to vaccinate all dogs against rabies.

Hästinfluensa, orsakat av ekvint influensavirus (EIV) förekommer över hela världen och är en vanlig respiratorisk sjukdom hos häst. Nyligen upptäcktes att EIV passerat djurslagsbarriären och orsakat sjukdom hos hund, vilket har lett till utvecklingen av canine influensavirus (CIV). Detta har sannolikt skett via direkt överföring utan föregående mutation av viruset. Flera faktorer spelar in i processen men den viktigaste tycks vara att häst och hund uttrycker samma typ av ytreceptorer i luftvägsepitelet (SA?2,3Gal), vilket möjliggör för EIV att binda in till och infektera cellerna hos både häst och hund.

Kennelhosta är ett samlingsnamn för en grupp virus- och bakterieinfektioner som ofta drabbar hundar som är tillsammans med större grupper av andra hundar. Symptomen är oftast milda, vanligtvis med en torr, hackande hosta, men kan i vissa fall ta sig uttryck som svårare symptom som lunginflammation. De vanligaste infektionsämnena är hundens parainfluensavirus (CPIV), hundens respiratoriska coronavirus (CRCoV), hundens adenovirus typ 2 (CAV-2) och bakterien Bordetella bronchiseptica. Hundens respiratoriska coronavirus är det virus som undersöktes i studien som ligger till grund för den här rapporten. Familjen coronavirus innehåller de största membranomslutna virusen med RNA som arvsmassa med genomstorlekar på upp till 32000 baser.

The aim of this study was to determine a method to habituate treadmill-naive Labrador Retrievers to walk and trot on a treadmill. 17 Labradors was equipped with reflective markers glued to the skin. Their motions were captured with six 240 Hz infra-red cameras as they walked and trotted on a treadmill three times a day for two days. Also the heart-rate was recorded. We then used QTM and custom built software to analyze the measurements.

During the cultivation season there are a several cropping activities to carry out. At what time these activities are carried out is affecting the result and also on the economy of the crop production. As the production costs are high in potato production, it is important to keep an eye on the economy. Profitability is the most important factor in most crop production systems. If the costs are not covered, it is difficult to justify the production.

Under åren 2005-2010 utförde en forskargrupp från Colorado State University studier på vaccinerade katter och fann att katter utvecklade antikroppar mot sina egna njurar efter vaccination med vanligt förekommande basvaccin mot parvovirus, calicivirus och herpesvirus. Virus till vaccinen är odlade på en celllinje från kattnjurar och går under benämningen Crandell Rees Feline Kidney. Antikropparna riktade sig mot antigen identifierade som annexin II och ?-enolas och man såg tecken på interstitiell nefrit hos 50 % av katter som hyperinokulerats med Crandell Rees Feline Kidney. Hos människa och mus har antikroppar mot ?-enolas och annexin II kopplats till autoimmuna sjukdomar och då framförallt immunologiska reaktioner mot njurcellerna.

Idiopathic pulmonary fibrosis (IPF) is a chronic respiratory disease with an estimated incidence of 3-6 cases per 100 000 inhabitants in Sweden. There is no cure for the disease, which inevitably leads to death. A similar disease has been found among terrier dogs, with an especially high prevalence in the West Highland White Terrier (WHWT). Dogs with pulmonary fibrosis become lethargic with exercise intolerance, and in some cases they develop cough and respiratory distress. This thesis gives a brief review of the field of pulmonary fibrosis and presents a method for analyzing surfactant proteins in bronchoalveolar lavage (BAL) in the dog.

The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

Background: Vaccination is an important part in cats? welfare. It both helps to prevent the individual cat from catching a disease or lessen the symptoms of it, and protects the entire cat population from an epidemic. It is the cat owner who makes the decision to vaccinate or not. Understanding the cat owners? perspective regarding vaccination may improve communication between the owner and the veterinary nurse, which may lead to a higher vaccination rate among cats.

Conjunctival swabs from 12 cats in a Swedish animal shelter were analyzed by real-time PCR for FHV-1, Mycoplasma felis and chlamydiae. The purpose of this study was to see whether and to what extent these agents can be detected and if they were detected from cats housed in quarantine or in the adoption department. Samples were first taken upon arrival at the quarantine and then a second sample was taken two weeks after moving to the adoption department, or upon presentation of signs of disease. The cats spent the quarantine period in two separate quarantines: five in a new quarantine (quarantine A) and seven in a room in the old shelter (quarantine B). The difference between these quarantines was that in B the cats were often mixed together ant the hygiene routines were not as good as in quarantine A.

I denna studie har förekomst av progesteronreceptorer i olika typer av primära juvertumörer undersökts med hjälp av immunohistokemi. Dessutom har tumörceller från carcinomcellinjen CMT-U27 odlats i olika cellodlingsmedium och exponerats för olika testsubstanser som binder till progesteronreceptorn (progesteron och RU486/mifepristone). Cellernas receptoruttryck och progesteroninnehåll utvärderades med hjälp av ELISA och tumörcellernas viabilitet analyserades med Colorimetric Cell Viability Test. Av resultaten framgår att samtliga undersökta primära juvertumörer uttryckte progesteronreceptorer. De odlade cellerna hade högre cellviabilitet när de odlades utan fetalt bovint serum (FBS). Efter exponering med progesteron minskade tumörcellernas uttryck av progesteronreceptorer, vilket hämmades av mifepristone.