Sulforafan är en isothiocyanat-förening som finns i stora mängder i olika kålväxter. Sulforafan har setts ha en kemopreventiv inverkan bland annat genom att inducera fas II-enzymer styrda av transkriptionsfaktorn nuclear factor E2-related factor-2 (Nrf2). Nrf2 är mycket viktig i cellers skydd mor oxidativ- och elektrofil stress och inducerar uttrycket av många olika gener, bland annat olika tranportproteiner. Breast cancer resistance protein (BCRP) är en av transportörerna som tros induceras av Nrf2. BCRP finns i stora mängder i lakterande juvervävnad men också i många andra vävnader där den transporterar läkemedel ut ur cellerna.

This study describes how the women lived with Breast cancer. The purpose with this study was to describe the womens' view on the disease and the understanding they hade on the social support they were depended on. The method was a study of literature with article reviews according to Polit et al., 2001. As theoretical frame of reference we choose Carnevalis model, Everyday life -Functional state of health. The result showed that the following four groups were formed: Support, positive and negative support off nursing staff and significant others.

Endast en procent av alla bröstcancerdrabbade per år är män. Det är ett område som är eftersatt i forskningen och dåligt uppmärksammat av både vården och samhället. Syftet med studien var att undersöka mäns upplevelser av att drabbas av bröstcancer. Den metod som användes var i form av en litteraturstudie med kvalitativ ansats. Urvalet bestod av sju vetenskapliga artiklar som fokuserade på mäns upplevelser av att leva med bröstcancer som sedan granskades utifrån Polit och Becks (2010) kriterier.

Narratives about life-changing events like cancer have become more common in today?s society. The purpose of the present study was to investigate whether gender patterns in society can also be found in pathographies about cancer, and further to investigate how gender is expressed in these cancer related narratives. Questions were posed on characteristics of the autobiographical cancer narratives, how gender is constructed by the authors of these narratives, and what these narratives say about gender structures? liability to change in the individuals affected by this disease.

Featured adjuvant chemotherapy treatment in women with Breast cancer can lead to pain. The aim of this study was to explore, the variety of perceptions and impact of adjuvantchemotherapy-induced pain in daily life, of some women newly diagnosed with Breast cancer.Inclusion criteria were participating in an ongoing stress management projectand chemotherapy of (anthracycline/taxan) in doses of 75mg² or more. Exclusioncriteria were inability to understand and communicate in Swedish and mentalillness. After ethical approval of the sub study in September 2010, women wereconsecutively included through oral and written request. Phenomenologicalapproach was used in the eight interviews and data analysis.

A lot of various substances can be detected by dogs, as oestrous in cows, endangered species or non-biological substances like accelerants, narcotics, explosives, mines and pollutions and biological substances like identity (suspects), cancer (breast, lung, colorectal and bladder cancer), human remains (cadaver), bacteria and mould in buildings. The dogs are trained using non-scientific methods and not much research in detection training exists. This is a review of different types of dog detection, with focus on new research..

Bakgrund: Övervikt och fetma är en global epidemi. Fetma kan orsakas av arv, miljö och beteendemässiga faktorer. Övervikt kanleda till flera följdsjukdomar. Viktminskning kan ge ökad livskvalité pch psykiskt välbefinnande. Ur ett hälsoekonomiskt perspektiv är det av vikt att det hälsofrämjande arbetet startar tidigt i barndomen.

Bakgrund: Bröstcancer är en sjukdom som drabbar allt fler kvinnor världen över, men samtidigt minskar antalet dödsfall på grund av säkrare diagnostiska metoder och behandlingsmöjligheter. Utöver konventionell mammografi har MR-mammografi vuxit fram och är idag en etablerad metod inom bröstcancerdiagnostiken. Syfte: Syftet är att belysa MR-mammografins betydelse för kvinnor som undersöks i avseende att utesluta eller upptäcka bröstcancer. Metod: Examensarbetet genomfördes i form av en litteraturöversikt där forskningsmaterial ur vetenskapliga artiklar granskades och sammanställdes. Resultat: Kvinnor med förhöjd bröstcancerrisk gynnas av att genomgå MR-mammografi.

Abstract? Background: ?Breast?cancer is the?most?common cancer for?women,?with?over 8000?of?cancer?cases?per?year.?Surgery?is the?most?common form?of?treatment. Basis?of?illness?and?the?loss?of?a?breast?can?be a?big?trauma for the?individual?and?affect?many?aspects.?Aim: The?aim?of?this?study?was?to?investigate?health-related?quality?of?life?and?psychosocial?situation and the?need?for support and?care?for?women?who?undergone?a?mastectomy?with?or?without?reconstruction.?Method: The?study?design?was?a?descriptive?study?with?qualitative?approach.?The?selection?was?strategically?consisting?of?the?eight?women?from?five?cities?which?had?undergone?mastectomy?with?or?without?reconstruction. The?interviews?were?semi-structured?individual?that?analyzed?using? content?analysis.?Results:All?of?the?women?felt?that?the?body?changed?after?the?mastectomy.? Feelings?of?insecurity?and?discomfort?were?common.?Among?those?who?underwent?reconstruction?were?all?dissatisfied?with?the?results.

Social support is an important part of handling the troubles of life. The purpose of this literature review is to investigate what forms the social support for adult women with Breast cancer with the aim to be used in the nursing care. By system-atical reading of scientific articles nine qualitative articles were found which the result is based on. The theoretical framework was Antonovsky´s health focused theory with the central issue KASAM, the feeling of life connection. The study resulted in three themes emotional support, practical support and informational support, which describe the balanced content of social support.

The efficacy of screening for Breast cancer with mammography has been a subject of controversy during the last decades. However, the general opinion is now that screening reduces mortality in Breast cancer (Zackrisson, 2006). It is nevertheless important to weigh the efficacy against the harm and costs associated with screening. Cost-utility and cost-effectiveness analysis of screening have generally failed to incorporate side effects such as anxiety and discomfort related to screening tests and the following diagnostic tests (Gyrd-Hansen, 2000). This study seeks to include such side effects in a cost-utility analysis.

The supportive role of nurses in psychological care of women with Breast cancer.

Featured adjuvant chemotherapy treatment in women with Breast cancer can lead to pain. The aim of this study was to explore, the variety of perceptions and impact of adjuvantchemotherapy-induced pain in daily life, of some women newly diagnosed with Breast cancer.Inclusion criteria were participating in an ongoing stress management projectand chemotherapy of (anthracycline/taxan) in doses of 75mg² or more. Exclusioncriteria were inability to understand and communicate in Swedish and mentalillness. After ethical approval of the sub study in September 2010, women wereconsecutively included through oral and written request. Phenomenologicalapproach was used in the eight interviews and data analysis.

For a woman who has been diagnosed with Breast cancer, there can be many negative things that effects her life. It is a great shock that changes her life and can include a sense of lost femininity and a decreased sexual desire which can be both physical and psychological. The basis of this literature review is from 17 scientific articles which evaluate the changes in cancer patient's body image and sexuality during their illness and treatment. This study illustrates patient's experience of the nursing and difficulties which obstructs the nurse from talking about sexuality whit the patient. The study also showed that the patient had a desire to discuss these sexuality issues with a nurse..

ABSTRACTObjectiveThe aim of this study was to determine if and what kind of scientific evidence there is for the advice that breast-feeding can reduce the risk of sudden infant death syndrome (SIDS). The aim was to investigate research on the subject published in the last 15 years.MethodA systematic review without meta-analysis with relevant original articles published in the last 15 years.Main resultsAfter searching for articles 26 relevant articles were used for this study and two were excluded because of poor quality. Mixed results were shown on breast feeding and the risk of SIDS. Breast-feeding seems to have some protective effect but can?t be separated from known risk factors of SIDS.Plain language summaryBreast feeding can be regarded as a preventive measure against SIDS.