The Center for Genomics and Bioinformatics (CGB) is an academic department at Karolinska Institute. Generally stated, the CGB department is committed to the generation and management of genetic information by approaches aiming at elucidating the connection between genes, protein and function.WiGID is a genome information database that is available through WAP (Wireless Application Protocol).Our version of WiGID is based on WML, PHP and PostgreSQL as a database server.One of the changes on the old WiGID application was the creation of a relational database with seven tables and one view, instead of the file that represented the database on the old version. We also changed the script language from python to PHP.The search engine ability has been extended with three new search alternatives for a user to choose from. Each choice leads to other, sometimes multiple choices.A GUI has been created for the administrator, to be able to insert information into the database.The structure of the search engine is primarily for narrowing down the search result on the phone display, thereby making the search efficient..

Weaning is one of the most critical events in the piglet production with problems such as growth check and post-weaning diarrhea as a result. The lighter the piglets are when the growth check occurs, the harder they have to get back to normal growth rate. Creep feeding of piglets is used to reduce the problems by increasing the weaning weight and adapting the digestive tract to a starter diet. Hodge (1974) showed that the sow?s milk can not provide enough nutrients for maximal growth rate.

Sahlgrenska Academy at University of GothenburgDepartment of Internal Medicine and Clinical NutritionTitle: ?What nutrition therapy has the best outcome on growth in preterm children and/or children born with low birth weight??Author: Josefine Nyström and Rebecca HammarSupervisor: Fredrik BertzExaminer: Frode SlindeProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: April 11, 2013Background: There is a number of reasons why a child is born preterm and with a low birth weight, for instance if the mother is underweight, smoking or exposed for malaria. The negative consequences of being born preterm or with a low birth weigth are many, both on long and short term. According to the WHO preterm birth is the most common direct cause of infant mortality. By providing the right measures in time when it comes to nutrition the mortality can be reduced considerably.Objective: To examine and summarise the scientific ground when it comes to the best nutrition therapy for preterm children and children born with a low birth weight.Search strategy: A systematic literature search was done in the databases Pubmed, Cohrane and Scopus.

Mastitis, inflammation in the udder tissue, caused by S. aureus is a big problem in dairy cattle production. It causes suffering for the cow and curing or replacing the infected cow is costly for the farmer. It is known that beef cattle also suffer from mastitis caused by S. aureus.

This review article presents the splicing process during messenger RNA maturation and how it is regulated by different Cis-regulatory RNA-sequence elements and splicing factors. A more detailed description of the process alternative splicing and its importance to the function of genes from the model organism Arabidopsis thaliana is also given. A single eukaryotic gene can by the process alternative splicing (AS) give rise to a number of functionally mature mRNA-molecules, which in turn encodes for structurally and/or functionally different proteins. During the course of evolution, the process alternative splicing has thus shown to be effective in increasing transcriptome and proteome diversity of most eukaryotic organisms. This suggests therefore that the dominant theory in molecular biology, a gene encodes for a protein, needs to be corrected.

Enligt den svenska skollagen (SFS 2010:800) har elever i skolan rätt till näringsriktiga skolmåltider. I lagtexten saknas förklaring om vad den näringsriktiga måltiden innebär, men regeringen hänvisar till de svenska näringsrekommendationerna som utgångspunkt. Syftet med denna rapport var att undersöka skolors tillvägagångssätt för att servera en näringsriktig måltid i skolan. Den kvalitativa intervjun användes som metod för att under-söka detta i fem skolor belägna i Uppsala kommun. Livsmedelsverket har skapat en vägledning, ?Bra mat i skolan?, som ger rekommendat-ioner för skolmaten baserat på de svenska och nordiska näringsrekommendationerna.

The study was carried out at the Kungsängen Research Centre, Department of Animal Nutrition and Management, Swedish University of Agriculture Sciences, Uppsala. The technical development in dairy production has resulted in a housing system where feeding and milking is done automatically without human contact, a so called automatic milking system. The motives for utilising an automatic milking system, is to increase the animal welfare and to decrease the need for manual labour. However, the system does involve a change for the animals, among the effects is the deprival or the diminishment of a chance for synchronous behaviour and the animals have to agree among themselves in which order they use the feeding stations and the milking unit itself. How and if this affects the animals well-being and production is yet to be solved. A possible way to form an opinion on this, is to study the animals ranking order along with hormone profiles and production. The purpose of this work was to study the effect of low- vs.

This study was performed in order to evaluate if the method of collecting uterine secretion by the tampon-method is representative for use in studies of uterine secretions in mares. Uterine secretion collected by tampon in six mares was compared with secretion collected by aspiration, regarded to be a native sample, at the Institution of Obstetrics and Gynaecology, SLU, Uppsala. Proteinanalysis was made at the Department of Farmaceutic Bioscience, toxicological unit, Uppsala University. Cytological smears and ultrasonography was used to assess if the tampon had caused an inflammatoric reaction that could influence the protein content of the samples. The results suggest that the tampon and aspirat method do not differ when it comes to proteinconcentration, but the distribution of proteins differ between these different collection methods. This difference could not likely be explained by means of proteins due to an inflammatory reaction from the tampon, since neither the cytological nor the ultrasonographical examination gave any indications of inflammation.

Fodermedelsallergi är ett tillstånd som beror på att immunsystemet reagerar mot något, oftast ett protein, som normalt sett inte ska utlösa ett immunsvar. De vanligaste symptomen är kutana symptom såsom klåda, alopeci och otit. Fodermedelsallergi diagnosticeras med hjälp av en eliminationsdiet med efterföljande provokation och vid diagnos behandlas sjukdomen genom att undvika det orsakande allergenet. För att inte utveckla fodermedelsallergi måste hunden eller katten utveckla en oral tolerans mot proteinerna i kosten; misslyckas detta kan allergi uppstå. Denna uppsats syftar till att sammanfatta den tillgängliga forskningen kring hur den orala toleransen uppstår, den immunologiska bakgrunden till fodermedelsallergi samt hur en eliminationsdiet påverkar immunsvaret.

Dairy cows transform grass to milk with help from ruminal microorganisms that can digest indigestible fiber in their feed. The digestive system of the cow is adapted to a diet consisting of forage and disorders like acidosis, laminitis and abomasal displacement can occur if the feed contains too much starch. To achieve the highest production possible the cow has to be given a high amount of concentrate or grain as the difference in milk yield is significant, approximately 1000 kg energy corrected milk per cow and year between conventional and organic cows that are fed a lower versus a higher share of forage. If the cow shall be able to eat the same amount of energy from forage as from grain or concentrate the eating- and rumination time gets longer and she might not be able to eat enough, which will result in a lower milk yield and will make it harder for the cow to recover from the negative energy balance that originate from the beginning of the lactation. Fat and in a sense protein content differs also depending on if the cow is given a high or low share of forage..

Trots global spridning av miso produceras den sällan på regionalt odlade grödor. Syftet med denna uppsats är att undersöka möjligheterna att producera fermenterade bönpastor med shinshu miso-karaktär på gula ärtor och korngryn. Metoden som använts i studien var litteraturstudie utförd på fyra vetenskapliga artiklar. De veteskapliga artiklarna hämtades från en databas med inriktning på måltidskunskap.Fermentering på andra grödor än de som vanligtvis används vid misoproduktion sker med goda resultat. Fermenteringstiden är avgörande för den karaktäristiska smak och färgkaraktären i miso.

Atopisk dermatit är en sjukdom som drabbar ungefär en tiondel av världens hundar. Sjukdomen ger som följd av allergenexponering symptom såsom klåda, hudlesioner och otitis externa. Patogenesen för atopisk dermatit är komplex och multifaktoriell. Målet med denna litteraturstudie var att undersöka hur genetiska och immunologiska faktorer bidrar till sjukdomens patogenes. En obalans i T-hjälpar-(Th)-svaret vid atopisk dermatit är allmänt accepterad.

Soja är den mest använda proteinkällan till fjäderfä i Sverige och mycket soja importeras i dagsläget. Då soja nämns mycket ur klimatsynpunkt, skövling av regnskog, minskad biologisk mångfald, är användning av svenskodlade proteinfodermedel som ärt, åkerböna och lupin av intresse. Ur odlingssynpunkt är ärt, åkerböna och lupin bra grödor i växtföljden då de är bra förfrukter. De passar även bra att odla i kallare klimat vilket gör dessa grödor intressanta att odla som proteinfodermedel i Sverige. Dock begränsas användningen pga.

Fotosyntesen kallas den process som omvandlar ljusenergi till kemisk energi. Fotosyntesen sker i tylakoidmembranet och drivs av två stora proteinkomplex, fotosystem II (PSII) och fotosystem I (PSI) då de tillförs energi i form av fotoner. PSI-N är ett mindre protein på ca 10 kDa som ingår i PSI. På något sätt, som ännu inte är klarlagt, samverkar PSI-N med PSI-F och plastocyanin när det dockar till PSI. Det är därför av viktigt att rena fram större mängder av PSI-N för att få djupare kunskaper om proteinet samt dess struktur och funktioner.

The relatively poor economy in European dairy farming might be improved from efficient feeding systems and dietary management. Increasing herd sizes and transition to loose housing systems in Sweden, increases the possibilities for other feeding systems than separate feeding that is the traditional feeding system in Sweden. Other possible feeding systems are partial mixed ration (PMR) and total mixed ration (TMR), where the TMR system sometimes is associated with overfeeding and thereby increased environmental impact and high feed cost. Diets providing nutrients above or below animal requirements are considered as unbalanced, which in turn are associated with reductions in health, fertility and milk production. On the other hand, a balanced feed ration improves feed efficiency, nitrogen utilization and profitability.