Sök:

Sökresultat:

1147 Uppsatser om Single cell genomics - Sida 13 av 77

Ställtidsreduktion med hjälp av SMED

Syftet för det här examensarbetet var att praktiskt reducera ställtiden på enbefintlig produktionslinje på Ruukki i Halmstad. Vid tiden då författarna togkontakt med företaget var den nuvarande ställtiden alldeles för lång och långtifrån optimal. I samband med projektets start gjordes det ett antal avgränsningaranpassat till den tiden som fanns tillgänglig.Tillvägagångssättet och metodiken till lösningen bakom ställtidsproblematikenföljer Shigeo Shingos Single Minute Exchange of Die (SMED), där har författarnautfört analyser i form av iakttagelser och tidtagning. Upptäckterna som gjordesunder analys samt implementering var att även om SMED är en direkt metodik förställtidsreduktion finns det andra faktorer som kan motverka implementeringensamt dess goda resultat. Dessa faktorer som påvisades under projektets gång varbland annat de mänskliga aspekterna och den bakomliggande företagskulturen iorganisationen.

TaqMan® Sample-to-SNP Kit? : evaluation of kit for low-cost and fast preparing of DNA-samples before genotype analysis

 Genotyping can be used to link genetic variation among individuals to certain diseases or conditions. Some known disorders and states that are dependent on single nucleotide polymorphism (SNPs) are lactose intolerance, venous thrombosis, hereditary hemochromatosis and the difference in sensibility among people to metabolise drugs.In this project a new kit, TaqManÒ Sample-to-SNP KitÔ for extraction of DNA and preparation of the extract for genotyping with real-time PCR and allelic discrimination, was evaluated. QIAamp® DNA Blood Biorobot® MDx Kit was used as the reference method.The purpose of the comparison was to find a method that makes DNA extraction from blood samples cheaper and faster, but with the same reliability as the reference procedure.The results of the evaluation showed a complete agreement of the genotype results between the methods tested, which means that the new method was as reliable as the reference method. The costs of reagents and material would be reduced with 52% if the new method is adopted, that alone would result in a cost reduction of 144 000SEK a year with a sample volume of 650 samples/month. The time for DNA extraction would also be reduced with the new procedure. .

Att leda förändring från mellanskiktet : -       En kvalitativ intervjustudie om första linjens ledares upplevelser av att leda en förändringsprocess

Första linjens ledares roll har under de senaste åren blivit mer ansvarskrävande. Vad är då viktigt för ledare i denna position då det kommer till att åstadkomma förändring? Finns det några utmaningar första linjens ledare stöter på? Denna studie syftar till att belysa första linjens ledares upplevelse av att leda en förändringsprocess. Två frågeställningar skapades; ?Vad anser första linjens ledare som viktigt i sitt ledarskap för att kunna åstadkomma förändring?? samt ?Vilka utmaningar möter första linjens ledare i en förändringsprocess??.

Integritet och långsiktig användbarhet hos textdokument : En avvägningsproblematik vid digitalt bevarande

This thesis is about a potential trade-off between integrity and long-term usability in the choice of file formats for preservation of text documents. Five common formats are discussed: plain text, PDF/A, Office Open XML Document, Open Document Text, and Markdown. The formats are compared with respect to four criteria related to integrity and usability and to the records continuum model: support by widely used software, stability, rendering of contents and reusability.It is concluded that no single format is optimal with respect to all four criteria, when it comes to preserving typical documents in a modern environment, with more or less complex formatting and document structure. Therefore, the feasiblity of using two or more formats for preservation of a single document (e.g. PDF/A combined with Markdown and/or Office Open XML) is discussed.

Bristen på arrendemark som hinder för expansion av lantbruksföretag : arrendelagstiftningens och gårdsstödets påverkan på den svenska arrendemarknaden

Improved profitability, a reasonable yearly income or the possibility to have employees are all incentives for expansion. A prerequisite for farm businesses to expand is for land to be made available, either to buy or to rent. In Sweden, 43 % of the total arable land is leasehold land, which implies that a functioning leasehold market is of great importance for the Swedish agriculture. Several factors can affect the supply of leasehold land, for instance the leasehold legislation and the Single Payment Scheme. The fact that the leasehold legislation is compulsory, in protection of the leaseholder, might keep land owners from leasing their land out.

Produktionsuppföljning på WilloMaskin AB

The purpose with this bachelor thesis is to identify risks and insufficiencies concerning the production at WilloMaskin AB. The project is limited to only 4 machines, where theories as ?OEE? (overall equipment efficacy) should be illuminated and analyzed. The theory of ?Single Minute Exchange of Die? is also presented.The method used in this project is mostly based on qualitative studies but also quantitative studies are presented.

Ett företags internationaliseringsprocess : - i ett land kulturellt skilt från dess hemmamarknad

AbstractPurpose:The purpose of the study is to describe the internationalization process of one firm when in a country culturally diverse from the firm?s original market.Methodology/approach:The study is a single case study which examines one firm?s internationalization process when entering the Chinese market. The approach has been an empiric interaction between empirical and theoretical data.Findings:The theory of the Uppsala model was applied to the case-company to test the model?s completeness. The authors found weaknesses and added three more aspects to the model.

Normalitet i adoption och föräldraskap : En kvalitativ studie av socialtjänstens medgivandeutredningar av ensamstående som vill adoptera

The aim of the study was to illustrate how single parents who want to adopt a child are described in consent investigations made by the social service. The methodology for this study was document analysis. The analysis material consisted of 23 consent investigations from family courts in 12 different municipalities and district administrations. The theoretical starting point of the study was the perspective of social construct of reality. Based on the issues of the study, background on international adoptions, theory of norms and deviation and past research the documents were analyzed.

EHV-1 och virusinducerad abort

Syftet med detta arbete var att redogöra för hur EHV-1 orsakar abort hos dräktiga ston samt patogenes och egenskaper hos viruset som leder fram till abort. Ekvint herpesvirus typ 1(EHV-1) är ett ?-herpesvirus som finns över hela världen och kan orsaka tre olika typer av sjukdomar hos häst: Respiratorisk sjukdom, neurologisk sjukdom och abort. EHV-1 överförs främst genom inandning av aerosoler från infekterad häst och orsakar först luftvägssjukdom och viremi. Viruset bildar sedan latens, främst i lymfknutor nära de övre luftvägarna samt i trigeminala ganglier.

Prevalence of subclinical mastitis and udder pathogens in small holder dairy farms in Mapepe, Batoka and Choma areas in Zambia

Subclinical mastitis (SCM) is a well-known problem in the dairy sector, where it causes severe economic losses mainly due to reduced milk production. This is a problem not only in the western world but also in developing countries. Surveys from different developing countries have shown a SCM prevalence of 52.4 ? 88.6 % at cow level and 26.7 ? 63.2 % at quarter-level. To combat mastitis is important to optimize the milk production of the cow.

Mixture and single-compound toxicity using Daphnia magna : comparisons with estimates of concentration addition and independent action

Aquatic organisms are usually not exposed to single substances but rather to mixtures of toxicants in streams located in agricultural areas. The transport of pesticides used in the agricultural area in Sweden is monitored with continuous environmental supervision every year. During 2002-2008 an average of 10 pesticides were found in each sample and 40% of the samples contained substances with concentrations higher than the Water Quality Standards. Chemical risk management is normally based on single-test evaluations. A problem when assessing mixture toxicities is that the constituents and concentrations of pollutants in the environment vary greatly.

Val med föremål och bilder hos barn i Tanzania med cerebral pares : En interventionsstudie

Previous research has shown that children with multiple disabilities have been able to learn to make choices. Practising choice making is a good way to introduce an intervention using Alternative and Augmentative Communication (AAC). Choice making with objects should then be trainded before choice making with pictures. The present study is a single subject experimental design and was accomplished at a center for children with disabilities in Tanzania during 12 weeks. The primary purpose was to examine if the number of choices made by two boys with cerebral palsy increased after communicationintervention with objects and pictures.

Validering av metoder för analys av Cu, Fe och Na i processvatten med AAS-grafitugn

Södra Cell Mörrum is one of the five paper pulp plants that are included in Södra Cell, and the paper pulp that is produced here is not only sold to Swedish paper mills. Most of the paper pulp is exported to different countries in Europe. In the manufacturing process the plant needs different kind of process water and there are guideline values for how much copper, iron and sodium this water is allowed to contain. Analyzes of this water is in the current situation done with an atomic absorption spectrometric instrument (AAS-instrument) with a flame. Measurements done with flame-AAS of samples that have concentrations near the guideline values for copper, iron and sodium, are not reliable. The reason for not being reliable is that the quantitation limits of these metals are higher than the limit values.

Arkeologi och den senmedeltida ödeläggelsen

This essay discusses the width of the late medieval desertion of farms in Sweden from an archaeological perspective. The object of the essay is to investigate if archaeological investigations and research during the last 10-15 years have changed the view of the late medieval desertion in relation to the Scandinavian research project on deserted farms and villages.The essay also deals with questions on causes to the desertion and when desertion occurred. An ambition of the essay is also to give a general picture of archaeological investigations during the last 10-15 years considering the late medieval desertion. The analyses-material consists mainly of reports from archaeological investigations.Most of the investigations analysed in this essay are investigations of single farms. Because of this it is natural these investigations do not say much about the width of the desertion.

Emulerad single sign-on

The goal of the project was to create an extension to Internet Explorer forStatens Tjänstepensionsverk (SPV) which would give the staff the experience ofSingle sign-on (SSO) to external web service providers as well as manage andupdate their passwords in a secure manner. The survey focused on the providersPalasso, ProCompetence and Wera. The extension was created as a BrowserHelper Object (BHO) with C# in .NET. The solution was implemented as aCOM object in a DLL-file that was running in-process with the browser. Theprogram used a locally stored XML file containing URLs, usernames andencrypted passwords to the providers.

<- Föregående sida 13 Nästa sida ->