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1147 Uppsatser om Single cell genomics - Sida 14 av 77
Kulturellt och psykiskt avstånd : En studie om EU:s inre marknad
Objective: The papers objective is to create a deeper understanding for whether or not cultural and psychic distance affects corporate establishments in the EU.Method: The results have been gathered through intense data collection through interviews with ScaniaAB and Business Sweden. There has also been extensive research of 36 different companies and their first establishments in different countries. We have then analyzed the results through cultural and psychic distance and through Uppsala University's internationalization process model.Conclusion: The conclusions of this paper are:Corporate establishment often occurs in neighboring countries because of the similarity to the domestic markets which contribute with a greater security.Since the introduction of the EU single market, corporate establishments have become easier within the single market.The cultural and psychic distance does exist within the EU, however the internal market decreases these distances and the impact on corporate establishments.The market commitment is essential to the corporates survival within the new market.Cultural and psychic distance affects small firms more often since their lack of network and experience.Cultural and psychic distances are two different but related phenomena..
A porcine type 1 Diabetes Mellitus model, for non-invasive in vivo imaging of the glucagon-like peptide-1 receptor in the pancreas, using [68Ga]Ga-DO3A-VS-Cys40-conjugated synthetic exendin-4 in PET-CT
Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls.
Eight Swedish high-health domestic pigs were randomly assigned to be either controls or made diabetic using streptozotocin (STZ). The experiment proceeded during eight weeks, starting with an acclimatisation period. Once the pigs had been socialised they underwent surgery for the insertion of a jugular vein catheter, allowing induction of diabetes with STZ, intravenous (i.v.) injections and stress-free blood sampling. Development of diabetes was confirmed by clinical examinations, blood glucose values and insulin-staining of pancreatic sections post mortem.
The diabetic pigs were insulin treated and responded well.
Växtinventering och skötselåtgärder : en studie av Rektorsgårdens trädgård i Uppsala
The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.
Varumärkesrätten inom EU : - ensamrätten i konflikt med EG: s konkurrensregler och reglerna om fri rörlighet för varor
The single market is one of the underlying ideas of the European Union. Free movement of goods and efficient competition are central for the function of the union and are therefore carefully protected by the Treaty of Rome. Exclusive rights of trademarks in the EU can be seen as a method of dividing the common market, preventing the free movement of goods and to be anti-competitive. What comes out of this is that there is a conflict between exclusive rights of trademarks and the rules of both free movement of goods and competition. The aim of this work is to see in which kind of situations the exclusive rights of trademarks can be a part of this conflict but also to study how this problem is resolved by the European Court.
Framtidens driftcentral : En analys av den framtida driften av ett svenskt elna?t
Active work to increase the efficiency of energy use is taking place in Sweden and throughout all of Europe. Electricity is an important part in our society?s energy system which means that the electrical grid operators and associated therewith has a central role in this work. Monitoring and controlling the electrical grids are managed from the distribution system operator?s DC, dispatch center.The aim of this report is to examine how the operations in a typical DC on the Swedish electricity distribution network will look like in five to ten years.
Kromatinstabilitet som grund för kvalitetsbedömning av hingstsperma :
This study is part of a project to evaluate and develop metods to control the semen quality in stallions. The study was carried out in cooperation between SLU and Flyinge AB. The objective of the study was to analyse
-if there are individual differences in sperm chromatin integrety between different stallions
-if there is a correlation between subjectively evaluated sperm motility and sperm chromatin integrity
-if sperm chromatin integrity is changed after selection of the semen with a centrifugation method through the silica-spheres, gradient or a single-layer, i.e to use the chromatin integrity analysis as a method to evaluate the selection method.
The use of chilled transported semen has increased a lot during the last 10 years, especially among the Swedish warmblood breed. Because the foaling percentage has decreased with the increased use of chilled transported semen, there is a need to develop methods to control the sperm quality. Evaluation of the chromatin integrity could be one way to evaluate the quality of the semen.
Chromatin is the DNA in the nucleus of the sperm.
Migrating Mesh SkinningDeformation Functionality fromRSX to SPUs on thePlayStation ® 3
In game development, performance is everything and the Playstation 3 provides a unique platform for utilizing parallelization of code to achieve extremely high performance. In this master?s thesis the issue of animation with smooth skinning is migrated from being a GPU process to becoming a parallelized and 358% faster process. This method is incorporated in an existing commercial game engine and integrated in a currently in development title for the Playstation 3. An in-depth study covers parallel processors, the CELL processor, used in the Playstation 3, and how contemporary industry leading game developers are utilizing the same unique architecture to increase their own games? performance..
Development of a real-time RT-PCR for quantification of bovine TLR4 mRNA and evaluation of its use during a BRSV vaccine challenge
The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.
Kvalitetsbedömning av selekterad och oselekterad hingstsperma med hjälp av flödescytometri och fluorometri, före och efter seminsäsongen :
Most Swedish Warmbloods are bred by artificial insemination (AI). Quality control of the semen consists of the subjective evaluation of motility. There is a need for a more accurate and objective method of rating the semen. In this study we compared fluorometry with flowcytometry as a method for evaluating sperm viability. Semen was collected from three stallions, stationed at Markebäcks Gård, Askersund, three times during week 15 and week 34, 2008.
Modeller för studier av ursprungsmärkt el
The EU has decided that it should be possible for consumers to get information about the origin of the electricity they buy. Therefore, there is a need to examine different systems for electricity disclosure. In this thesis two ways of disclosure have been studied:? Certificate system. A certificate system involves two parallel markets, one for trading electrical energy and one for trading certificates of origin.? Separated Markets.
Det sociala arvet : Kvantitativa analyser av intragenerationell (föräldrar till barn) överföring av utbildningsstatus och föräldra bakgrund
The aim of this study was to find relations between parents background and education ina wider sense and their children's success in school. The study also includes genusdifferentiations, the family profile and residential areas influence on children's ability anddetermination to study.The study confirmed earlier research that children's success in school is to some extentdependant on their parents education. At the same time it was shown that in most casesthe children reached higher level of education than their parents ? also when they werepoorly educated or had emigrated from a country with big cultural differences. It was alsoevident that children with at least one Swedish parent (and presumably Swedish as theirmother tongue) reached higher educational levels than other children.Children from single parent families often stopped their school carrier after the 9-yearcompulsory class while children of dual parent families more often continued to university.In general, girls were more affluent in school than the boys.
Hur kan organisationer gå från att vara samlare av informtion till att bli nyckeltalsanalytiker? : En fallstudie på Trafikverket
In 1993 the internal market within the European Union was formed and ensured free movement of goods, services, capital and people. This led to the removal of trade barriers between members of the European Union. When opening up for competition, price differences between countries decreased and more jobs were created. A single currency was introduced by eleven countries in 1999 with the goal of reducing transaction costs, eliminating exchange rate risk and to further simplify trade. In 2001 Greece joined the collaboration and introduced the euro.
Evaluering av återvinningseffektiviteten i Svensk Medicin och Google Scholar med medicinska frågor ur Fråga doktorn.
The purpose of this thesis is to evaluate and compare the retrieval effectiveness of two search engines on the Internet: Svensk Medicin and Google Scholar. Svensk Medicin is a medicine-specific search engine and Google Scholar specialises in indexing scholarly material. A set of 20 questions in four categories were used to conduct the searches with the search engines. Genuine medical information needs were selected from a question collection provided by the television program Fråga doktorn. The relevance of the first 10 retrieved documents was judged by using a binary scale and the measure used was precision.
Invandrares upplevelser av diskriminering och den politiska diskursen om invandrare i Sverige mellan 1960-2009
Aim: This paper aims to produce a serviced office concept adjusted to Statens fastighetsverk. The concept will make SFV:s properties more attractive for renting. Method: Information has been collected from interviews with 13 different serviced office companies, one serviced office agent and eleven government authorities. Also litterateur, reports and internet have been used in gathering information.I will use following questions:¨ How is the serviced office concept designed?¨ Which customer segment should SFV direct to and what need does the segment have?¨ How shall a marketing plan look like for the concept?¨ How should a concept designed for SFV look like? Result & Conclusions: Serviced office space is a company that letting functional workspace with access to shared facilities e.g. reception, office machines, internet, phone and more.
Use of feline TK1 as a biomarker in disease monitoring
Serum thymidine kinase 1 (TK1) activity is used as a tumor marker in disease monitoring in veterinary and human medicine. TK1, an intracellular enzyme, is involved in a salvage pathway of DNA precursor synthesis.
TK1 is used in DNA precursor production by catalyzing the transfer of the gamma-phosphate-group from a phosphate-donor to the 5?- hydroxyl-group of thymidine forming thymidine-monophosphate. Nucleoside monophosphosphates are finally converted into thymidine-triphosphates. TK1 activity significantly rises in the G1 and the S phase of the cell cycle.