Vectors based on lentivirus backbones have revolutionized our ability to transfer genesinto many cell types. Lentiviral vectors integrate into the chromatin of target cells and do not transfer any viral genes causing vector replication. Both of these features arecommonly used in gene therapy and have been used clinically in individuals sufferingfrom cancer, infections and genetic diseases. It has been discovered that T-cells can be genetically modified to be used as effective weapons against cancer: therefore virus mustbe produced to deliver the gene of interest into the T-cells. In this project, lentiviralvectors have been produced to transfer the gene coding for a chimeric antigen receptor(CAR) which is directed to CD19 on B-cells.

AbstractThis essay is about what rights that a consumer has, after it?s been to a beauty-shop getting a treatment somewhere on her body. We were interested to see what kind of regulations that could be useful if a problem occurred after or during treatment. There are several risks with these treatments.The last decade these kinds of treatments have increased, due to people being vain and so aware about there looks. We started to investigate what type of rights the consumer generally has when it?s about a service.

Jag har alltid fascinerats av kaffekannan i silver, hur tydlig den är i sin form och hur den bär på en tradition inom användandet såväl som utförandet. Det finns en tyst överenskommelse hur en kaffekanna ser ut och hur vi betraktar föremål med en tydlig funktion.Ur silversmedens synvinkel fungerar kaffekannan nästan som en ikon. Detta är något som håller på att försvinna i och med att kaffekannan i silver inte används på samma sätt i dag som den gjorde förr..

LGBT people, in Uganda, have since the colonial time been in a vulnerable situation. When the President signed the ?Anti-Homosexuality Act? into law 2014 all forms of same-sex relationships became criminalized. The time after the law passed have been characterized by an increased homophobia and further violence against LGBT people. These are seen as deviants since they do not live according to the social norms, that the right thing to be is heterosexual.

The main purposes of this study were to 1) quantify bacterial production in winter during ice conditions, and 2) to compare these production measures with values measured from summer and open water conditions in three humic lakes situated in northern Sweden. Another purpose of this study was to 3) examine whether clear-cutting significantly affected bacterial production or water chemistry in two lakes situated in catchments were a large part of the forest had been removed through logging compared to an undisturbed reference lake. In winter (March/April 2014), the bacterial production ranged from 0, 7 - 2, 2 µgC/L/day and in the summer of 2013 the production values was 4 ? 10 times higher. The main reason for lower bacterial production in winter was ascribed to lower water temperatures as well as to older and more recalcitrant DOC, as there were no significant differences in total dissolved nitrogen or DOC concentration or -quality, that could explain a lower production compared to summer.

Many tropical rain forests has been lost or degraded as a result of human activities and environmental factors. Since the level of biodiversity is high in the tropics, maintaining these areas is of great importance. Forests like these are often assumed to benefit from forest restoration and rehabilitation. The INIKEA project area in Eastern Sabah, Malaysian Borneo, aims to improve biodiversity and/or species richness in the degraded forest through enrichment planting with indigenous species. The objective of this thesis was to evaluate how different treatments (liberation, gap-cluster planting and line planting) affect the biodiversity of natural regeneration in different forest types in the Rain forest Restoration Experiment, located in the INIKEA project area.

The resting area is the most important place in the barn for the dairy cow, sometimes called the heart of the free stall system. Inadequate design of the lying area, and lack of or poor quality of bedding materials may reduce the hygiene of the stall. Poor management regarding the cleanliness of the resting area may lead to poor animal hygiene and increased bacterial growth. This in turn will lead to increased risk for environmental mastitis as well as impairing milk quality through contamination with spores. In this literature study the most commonly used bedding materials; straw, sawdust, wood shavings, clean sand, recycled sand, peat and recycled manure solids, are compared to one another with regards to their ability to resist bacterial growth. Effects of adding hydrated lime to bedding materials have also been studied. Most bacteria need humidity and prefer a quite high water activity to be able to grow.

About 10 % of the adult women population in Sweden are treated annually for urinary tract infections. The increasing bacterial resistance towards antibiotics is classified by WHO (World Health Organization) and ECDC (European Centre for Disease Prevention and Control) as one of the greatest treats for human health in a global perspective. To find alternatives scientists are studying the possibility to use probiotics to reduce the frequency of recurring urinary tract infections. This literature study examines five randomized double blinded placebo controlled studies where different strains of Lactobacillus have been used as a prophylactic to women suffering from recurrent urinary tract infections and bacterial vaginosis. Overall the studies do not display enough promising results to recommend the use of probiotics as a prophylax or cure..

The aim of this study is to elucidate factors that effect growth of Sarcina lutea and Bacillus subtilis, exposed to the growth inhibitor SDS (Sodiumdodecylsulfat). Agar diffusion experiments revealed repeated, concentric zones of inhibition and stimulation upon exposure to Sodiumdodecylsulphate or to Amoxicillin. Temperature, nutrient concentration and inhibitor concentration were controlled. Formation of successively repeated zones of inhibition, stimulation, inhibition and stimulation is discussed: ? The extension of the primary inhibition zone is due to the concentration of applied Sodium dodecyl sulphate.? Immediately outside the primary inhibition zone the bacteria have access to diffusing nutrients that have not been consumed in the primary inhabitation zone.? In zones of dense bacterial growth the bacteria may produce inhibiting substances, affecting growth of bacteria in adjacent zones.? In zones of dense bacterial growth the nutrients will soon become depleted, thus affecting bacteria in adjacent zones..

The purpose of this essay is to explore the actor network of a high technology company in the textile industry called F.O.V. Fabrics. The background for doing this is a recent project, which we choose to call the Salt & Paper Battery Group, aiming to commercialize a newly discovered technology ? a battery based on cellulose from an alga. We start by examining a range of network theories in order to eventually shape a framework of our own.

Fotorealistiska 3d-bilder används idag inom ett brett spektrum av branscher. Framställningen av denna typ av grafik kräver ofta väldigt mycket datorkraft. Vid rendering med renderingsmotorer som använder sig av raytracing algoritmer är aliasing ett medfött problem. Lösningen heter anti-aliasing som arbetar för att undvika aliasing artefakter som jagged edges eller Moiré-effekter med mera. En del av anti-aliasingprocessen är supersampling som ofta kräver mycket datorkraft.

The ambition to use evidence based treatments has spread within the field of Swedish social work. The number of treatments with claim to being evidence based has grown but the research concerning implementation; the procedures being used to introduce new methods in organizations and assure that the method is being used appropriately and continuously, is scarce. The aim of this study was to examine the implementation of Functional Family Therapy (FFT), being an evidence based treatment, in an organization providing social services in the public sector, in Sweden. We used a qualitative research design and conducted interviews with persons involved in the implementation of FFT in the social services in a town in the south of Sweden. We used the practice guidelines provided in Evidence Based Practice (EBP) together with recently published meta- analyses of implementation research, in the field of social work, to examine the implementation of FFT, as being an evidence based treatment.

Organic material used for biogas production can also undergo other treatments. The emissions and impact from the different treatments are evaluated in this environmental assessment, with a focus on energy and climate. The materials included in the study are organic household waste, slaughterhouse waste and liquid manure. Other than biogas production, the possible treatments for organic household waste and slaughterhouse waste are incineration and composting, and for liquid manure storing and spreading. The analysis is based on data and information from current and relevant literature, and relates to the conditions in the Swedish energy system.

With varied electoral success for anti-immigration parties across Western Europe, Sweden is often held as an example where anti-immigration parties have been less successful. This have caught the interest of many scientists around the world and have recently developed theories on a subnational level when testing Sweden?s municipalities, on why they have failed here but not in other countries. But in the election to 2010, Sweden now joins the rest of the Western-European countries in having an anti-immigrations party in the parliament.This paper has tested three theories on a Municipality that has shown evident support for the Sweden democrats, both in the local and the national election. This is done with a qualitative approach, made up from interviews with the local established parties.

My purpose in this work was to find out how staff in a middle sized school uses its local Equal treatment plan in its work against bullying. But also to see how the use of a standardized anti-bullying program works to prevent bullying. I have interviewed the principal, teachers, and what we in Sweden call a ?fritidspedagog? and the members of the anti-bullying team to get answers to my questions.  The conclusion of this study is that the school follow and work according to what the Equal treatment plan states, both in terms of prevention, as in working with actual bullying cases. The school has also followed the National School Agency's recommendations on what should be the local Equality plan, but also to follow up and revise it each year. The interview shows that the staff at the school placed great emphasis on talking and discussing with students about how to behave towards each other, they also brought up things that happened at one time and talked about this. The staffs were very committed to work towards the prevention of bullying and the same was true with the school's headmaster.