Sahlgrenska Academyat University of GothenburgDepartment of internal medicine and clinical nutritionAbstractTitle: Can supplementation with vitamin E improve cognitive function in Alzheimer?s disease?Author: Malin Andersson and Elin LöfqvistSupervisor: Elisabet RothenbergExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: 2012-04-11Background: Alzheimer?s disease (AD) is the most common form of dementia. As the average life expectancy rises the prevalence increases. The disease leads to gradual deterioration of cognitive functions. A recent Cochrane review describes how several studies demonstrate an increased oxidative damage in the brain in those with AD.

Sahlgrenska Academy at University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: Can peppermint oil relieve the symptoms of IBS?A systematic reviewAuthor: Caroline Månsson and Linn RamströmSupervisor: Fredrik BertzExaminer: Frode SlindeProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 23, 2013___________________________________________________________________________Background: An estimated 7-10% of the world population suffers from Irritable BowelSyndrome (IBS), a disease that greatly affects the daily life and the quality of life of the afflicted.The total annual health care cost of IBS is around 1280 billion Swedish crowns. IBS ischaracterized by abdominal pain/discomfort in combination with diarrhoea, constipation, or acombination of these. The etiology is unknown but it is believed that there are several factors thatcome into play. The disease cannot be cured, but there are ways to alleviate the symptomsthrough a variety of medicinal preparations and dietary treatment.

- To be trapped in a roller-coaster That ?s how some of the patients are describing the situa- tion of living with heart failure. To be stuck in their home not knowing if they will have to seek care today and not knowing if they will have the energy to attend that birth- day party later this week.Each year 2-3% of the Swedish population are diagnosed with heart failure, which results in 30,000 new individu- als with the disorder. Cardiovascular disease is rapidly in- creasing in the world and before 2030, people with heart failure will increased by 100%. Our improved living condi- tions and better health have allowed us to grow older and made us more dependent on other types of care, care at home.Today the patients are only looking for changes in weight and if they have excessive water in their body.

In veterinary medicine, penicillin is the most used antibiotic in Sweden. Two dosage forms of penicillin are available in Sweden for use in horses, sodium benzylpenicillin (Na-pc) and procaine benzylpenicillin (proc-pc). Proc-pc is the most used dosage form and is used for intramuscular administration which allows horse owners to treat an animal at home under veterinary instruction. Na-pc is only approved for intravenous use in horses. Penicillin is normally well tolerated by horses but a serious, sometimes life-threatening, adverse reaction called penicillin shock may occur.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: Coconut fat?s effect on blood lipids - A systematic overviewAuthor: Linnéa Hult and Sandra WestlingSupervisor: Fredrik BertzExaminer: Ingrid LarssonProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: 2013-04-11Background: Coconut fat has recently been praised in the media. Amongst other things,coconut oil has been said to lower cholesterol (1, 2). This despite the fact that coconut oilcontains of 92 % saturated fat, which strong scientific evidence support raises the blood lipidsand thus increases the risk of cardiovascular disease (3).Objective: To examine the scientific evidence for how blood lipids in adults are affected byan intake of coconut fat compared to an intake of other kind of fats.Search strategy: PubMed and Scopus have been used in the literary search. Keywords usedwere "coconut fat", "coconut oil", "plasma lipids" and cholesterol [MeSH].Selection criteria: Human studies of RCT or cohort type, published since 1983.

BakgrundTraditionell och komplementär eller alternativ medicin, vilket benämns Complementary and Alternative medicine (CAM), är enligt WHO en viktig, men ofta underskattad del i nationella hälso- och sjukvårdssystem. Användandet av CAM har ökat signifikant senaste åren för gravida kvinnor. Inom CAM ryms begreppet ?mind-body interventioner? eller ?mind-body therapies? och innefattar behandling så som mindfulness, yoga, akupunktur, massage. Yoga och mindfulness har enligt tidigare studier positiv inverkan på graviditet och graviditetsutfall.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: Is pricing a way to affect share of fruits and vegetables in a diet?Author: Maria PopovSupervisor: Heléne Bertéus ForslundExaminer: Ingrid LarssonProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 23, 2013Background: Fruits and vegetables (FV) are important for health, including occurrence of diabetes, obesity and cardiovascular diseases. Said diseases cause most cases of illness and death in high-income countries. Only a small part of the population achieves the FV-intake goal, so a higher FV-intake is desirable. Besides general information campaigns there is another method of influencing what people might buy.Objective: To examine whether different pricing is connected to FV-intake or ?purchase.Search strategy: Databases PubMed, Scopus and Summon were searched with ?vegetable consumption", "price/pricing policy" and "food choice? in different combinations.Selection criteria: Studies performed after year 2000 on at least 18 years old persons from North America, Europe or Australia, examining changes in FV-price and -purchase.

Veterinary medicine is not merely an area of occupation but also an area of business. In a business the customer service is its identity and brand and more importantly what makes the client choose and recommend the clinic to other potential customers. The licensed veterinary nurse is habitually the one who first meets the clients at the clinic. Therefore it is particularly important for the licensed veterinary nurse at the clinic to offer high-quality customer service. The object of this study was to understand and elucidate how the pet owners experience the encounter with the licensed veterinary nurse at different stages in their contact with the clinic.

Sahlgrenska Academy at University of Gothenburg Department of Internal Medicine and Clinical NutritionAbstractTitle: Can probiotics prevent atopic dermatitis in children with high risk?Author: Laura Pienihäkkinen and Max OlinSupervisor: Heléne Bertéus ForslundExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 22, 2012Background Allergic disease is today common, this including atopic dermatitis, which is the most common inflammatory skin disease in the world. Heredity has been shown to play a major role in the development of this disease. It is therefore of high interest for both the individual and society to find effective methods for preventing atopic dermatitis in individuals with high risk profile. Probiotics are beneficial for the bacterial profile in the intestine and it is therefore of interest to study if they through their anti-inflammatory effect could prevent atopic dermatitis.Objective The aim was to study whether administration of probiotics to the mother and the child (directly or via breast milk) could prevent atopic dermatitis in children with high risk profile (at least one first degree relative with a diagnosed allergic disease).Search strategy A systematic literature search was done in databases PubMed and Scopus with search terms maternal, prenatal, probiotics, allergy, atopic dermatitis, prevention, and children.Selection criteria Randomized, controlled human studies and original articles in English were included.

Introduktion: Läkemedelsverkets generella rekommendation är att naturläkemedel ska sättasut inför anestesi. Litteratur tyder på att läkare sällan frågar om naturläkemedelsanvändning iden preoperativa bedömningen, samtidigt som patienten sällan uppger sådant användande. Attha väsentlig information om patienten inför anestesi är en förutsättning förhandlingsberedskap för anestesisjuksköterskan, vilket gör säker och tydlig kommunikation tillen viktig del i patientsäkerheten.Syfte: Syftet med denna studie var att kartlägga huruvida anestesiologer beaktar patientersanvändning av naturläkemedel inom anestesi.Metod: För denna kartläggning genomfördes en kvantitativ enkätundersökning riktad motanestesiologer inom Sahlgrenska Universitetssjukhuset. Enkäten bestod av nio slutna och tvåöppna frågor. Kvantitativ data analyserades i SPSS och redovisades med frekvenstabeller,medan samtliga kvalitativa data redovisades med citat.Resultat: Inom ramen för denna pilotstudie delades tretton enkäter ut, varav elva besvarades.Könsfördelningen av respondenterna var 64 % (n=7) män och 36 % (n=4) kvinnor ochrespondenternas läkartjänster inom anestesi var ST-läkare 36 % (n=4), överläkare 36 % (n=4)samt specialistläkare 27 % (n=3).

Wounds on horses are common and sometimes difficult to treat. The wounds are often big and could be discovered too late for primary sutures, which have to be applied within 8 hours from time of accident, before bacteria has been able to infiltrate the surrounding tissue. The healing is often complicated by delayed healing and wound infection with consequences like phlegmone, fistulation and proud flesh formation.To avoid these consequences, the traditional practice has been to administer systemic antibiotics alone, systemic antibiotics in combination with topical antibiotics or topical antibiotics alone. Because few antibiotics can be used in horses, is it important to household with the few substances that are available. In veterinary medicine today, the increasing resistance amongst pathogenic microbes such as MRSA presents a growing problem.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionTitle: The effect of the glycemic index of breakfasts in energy intake inchildren and adolescentsAuthor: Charlotte Olofsson, Cornelia Johansson and Maria NordbeckSupervisor: Fredrik BertzExaminer: Ingrid LarssonProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 16, 2013Background: The glycemic index (GI) and it´s effect on energy intake is a debated subject.Research has been done whether food with lower GI decreases hunger and lowers energyintake, which could be an effective tool to prevent overweight in children and adolescents.Breakfast eating is successful for maintaining a healthy weight and it´s therefore interesting tosee if the quality of the carbohydrates matters.Objective: To evaluate the scientific evidence regarding the effect of GI of breakfasts inchildren?s and adolescents energy intake.Search strategy: To find relevant articles, a systematic literature search was made in thedatabases PubMed, Scopus and Cochrane. Search terms that were used were: breakfast,breakfast quality, children, glycemic index, energy intake, obesity.Selection criteria: Randomized controlled trials and cohort trials, breakfast eatingindividuals, children and adolescents under 18 years old, reported glycemic index. Outcomemeasurements: Energy intake.Data collection and analysis: Six original articles met the inclusion criteria and werereviewed by the SBU audit template for randomized and controlled studies. There after onearticle was excluded because of very low quality of the study.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: Effects of isoflavone supplementation from soybeans on LDL-cholesterol levels in adultAuthors: Malin Blomgren Alegria and Ruut ReivaaraSupervisor: Lena HulthénExaminer: Frode SlindeProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: 2013-04-08Background: One of the most common causes of death in Sweden is due to cardiovascular diseases such as heart attack and stroke. Hypercholesterolemia is one of the risk factors for cardiovascular disease. In Asia, hypercholesterolemia is less common than in the Western countries. In Asian countries, soy products are consumed in larger quantities than in the Western world, which has led to implemented research with the intention of examining soy's potential effect on cholesterol levels.Objective: To investigate whether there is scientific evidence that isoflavone supplementation from soy bean may have a lowering effect on LDL-cholesterol.Search strategy: The databases used for the systematic literature search were PubMed, Scopus and Cochrane. Keywords used were cholesterol and 9 versions of this, and isoflavones and 11 versions of that.Selection criteria: RCT articles, on humans, written in English, published from 2011 onwards, that focused on interventions with isoflavones from soybeans and its effect on blood cholesterol, the participants were over 18 years old and the study time was at least 24 weeks.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: Whole fat versus low-fat dairy products for primary prevention of cardiovascular disease. A systematic review.Author: Josefine Lindqvist, Robin Järnmark, Mathilde OhlinSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: 2014-04-09BackgroundResearch indicates that dairy products seems to have a protective impact on the incidence of cardiovascular disease regardless fat content. Paradoxically the Nordic nutrition recommendations recommend an exchange of full fat dairy product to low-fat dairy products.ObjectiveThe aim of this review is to investigate whether the variation in fat content of dairy products have any bearing on the onset of cardiovascular disease. With regard to common risk markers for cardiovascular disease the outcome measures hypertension, hyperlipidemia and weight gain is examined.Search strategyThe searches were made in the databases Medline (23/1-14) and Scopus (6/2-14).Selection criteriaRestrictions: Human Studies, Adults, Randomized Controlled Trials, English.Data collection and analysisTwo RCTs were included. Validation of the separate studies was performed with SBU's review template for individual studies and GRADE was used for summarizing the evidence of outcome measuresMain resultsThe two included studies examined the outcome measures blood pressure, weight and blood lipids.

Sahlgrenska Academy at University of GothenburgDepartment of Internal Medicine and Clinical NutritionABSTRACTTitle: The connection between IBS and FODMAPsAuthor: Helena Hautamäki and Rebecka BertilssonSupervisor: Sofia KlingbergExaminer: Frode SlindeProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: 2013-04-10Background: IBS (Irritable Bowel Syndrome) is a functional gastrointestinal disorder, and is acommon disorder in the western population. The predominant symptoms are diarrhoea,abdominal pain, bloating, constipation, and excessive flatus. Today there are no evidence basedrecommendations concerning dietary factors for patients diagnosed with IBS, but recently certainfactors in the diet that seems to trigger the symptoms have been identified. These factors areshort-chain carbohydrates, Fermentable Oligosaccharides, Disaccharides, Monosaccharides, andPolyols (FODMAPS), which are not completely absorbed in the lumen.Objective: The purpose of this systematic review article is to examine whether there are anyevidence that a diet low in FODMAPs may induce improvement of symptoms in patientsdiagnosed with IBS.Search strategy: The literature search was performed in the databases PubMed, Scopus,Summon and Google Scholar. The keywords were ?Irritable bowel syndrome + FODMAPs?,?Irritable bowel syndrome + diet? and ?FODMAP and diet?.Selection criteria: The inclusion criteria were patients diagnosed with IBS between the ages 18and 69.