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8339 Uppsatser om Clinical research - Sida 3 av 556
Ultraljud som diagnostiskt hjälpmedel vid subklinisk mastit hos ko :
This study was performed to investigate the possibility to use ultrasonography as a diagnostic tool for sub-clinical mastitis in dairy cows. Five cows with high cell counts, and four cows with low cell counts were selected as cases and controls, respectively, and their udders examined with ultrasound during a 5 week period. The image of the udders of cows with high cell counts exhibited small, hyper-echoic, rounded foci, approximately 1 cm in diameter, near the milk cisterns and the base of the teats. These changes were not found consistently in all cows with high cell count, however. Ultrasonography may be a valuable complementary tool in the diagnosis of sub-clinical mastitis in dairy cow, but more cases need to be monitored before its full value can be ascertained..
Sjuksköterskestudenters upplevelser och erfarenheter av den verksamhetsförlagda utbildningen och hur den påverkar deras syn på omvårdnad
sjuksköterska (I. Dahl).
Validering av Alberta Context Tool (ACT) för bruk inom svensk kommunal äldrevård : Ett verktyg för implementering av evidensbaserad vård
The aim of this study was to conduct an instrument test of the Canadian questionnaire Alberta Context Tool (ACT) version Long-Term care for Swedish conditions. ACT is designed in order to measure the context in the care environment and different behaviours related to the changes in clinical practice. In total, 159 Licensed Practical Nurses (LPNs) and Registered Nurses (RNs) within municipality care of the elderly were included in the survey. The test included the instrument's reliability and face validity.The reliability test was implemented through calculation of Cronbach´s Alpha, and showed internal consistency for five of the scales of the ACT-instrument with Cronbach´s Alpha values ranging between 0,728 and 0,873. However, three dimensions got lower values (0,558 - 0,683).The analysis was carried out with content analysis and carried out for LPNs and RNs in separate groups.
Kvalitet-i-Bruk för Beslutstödssystem inom Thoraxkirurgi
The aims of the practical work carried out for this thesis were to redesign a clinical decision support system for thoracic surgeons, called AssistMe, and to evaluate the concept behind this system. The main objective of the thesis is to give an account of the considerations that were found to be of key importance for designing a clinical decision support system for thoracic surgery. Another aim was to let future users test the system after it had been redesigned and evaluate the concept behind it. The thesis also investigates users? experience of the system and their views on whether it would be applicable in their daily work practice.
Fyra forskares informationsförsörjning och bibliotekets roll i denna process : en fallstudie på AstraZeneca R&D i Lund
Information is essential in order for pharmaceutical companies to be successful. This essay focuses on the information provision of pre-clinical scientists at AstraZeneca R&D Lund, and the role of the company library in this process. In semi-structured interviews, four pre-clinical scientists were asked to describe their information provision regarding what type of information they need, how they find it and what sources of information they use. Four librarians from the company library were also interviewed to give their perspective on the information provision of pre-clinical scientist. The study also aimed at comparing the image of the process as described by the scientists themselves and the librarians.
Fastställande av referensintervall för fibrinogen i plasma hos friska föl :
Establishing a reference interval for plasma fibrinogen in foals
Fibrinogen concentrations were analysed in EDTA preserved blood plasma samples from 34 thoroughbred foals born in 2001 and 2002 at one stud farm. The foals were between 0 and 240 days old at the time of the sampling, and there were 19 fillies and 12 stallions in the group. The foals were examined for clinical symptoms of disease and their body temperature was measured before blood was sampled from the jugular vein. From totally 156 blood samples, 31 were selected as originating from clinically healthy foals, and used to determine a reference range for thoroughbred foals. Samples originating from foals showing clinical symptoms of disease or an abnormal body temperature at the time of sampling, were classified as coming from unhealthy animals.
Patho-anatomical studies on african swine fever in Uganda
African Swine Fever (ASF) is one of the most serious transboundary swine diseases because of its high lethality for pigs, socioeconomic consequences, rapid and international spread and the absence of either treatment or vaccine. This Sida Minor Field Study (MFS) was carried out during fall 2010, as part of a larger collaborative research project called ASFUganda, focusing on the epidemiology of the disease in Uganda. The aim with this study was to get more knowledge about the pathology in cases of ASF in Uganda, by studying macroscopic and microscopic lesions in pigs with acute and chronic ASF and to detect the ASF virus (ASFV) in tissues by immunohistochemistry.
The pigs were selected from the two different geographical locations in Uganda, Mityana and Gulu district, both with on going confirmed outbreaks of ASF. Necropsies were performed in the field, and the laboratory procedures at the JICA (Japan International Cooperation Agency) Veterinary Pathology Laboratory, Entebbe, Uganda, and at the Department of BVF, SLU, Uppsala, Sweden. Three pigs from an outbreak of ASF in Mityana district showed both the history and the clinical symptoms typical for ASF.
Socialtjänstens barnskyddsarbete En studie av socialsekreterares riskbedömningar avseende barn som utsätts för våld eller sexuella övergrepp i hemmet.
The overall aim was to examine how the public interest to protect children from violence and sexual abuse at home, is realized by social workers. The study´s central focus was the risk assessments as Social services are obliged to do when they receive a report containing concern that children are being exposed to violence or sexual abuse at home. The study addresses the following questions:o How do social workers go about practically, and what support and knowledge is being used to determine whether the Social services need to intervene for the protection of a child?o What risk and protective factors are taken into account by social workers in the assessment process?o What contextual factors do social workers experience are affecting them in the assessment process?o Which support does the documentation system BBIC provide in the assessment process?The study material was collected through qualitative group interviews, with a modified vignette methodology as tools. The study included a total of twelve social workers, with varying numbers in each interview group.
Man kan aldrig så noga veta? mentalisering i familjeterapi
Syftet med uppsatsen var att undersöka och beskriva hur man arbeta med mentalisering/ reflektiv funktion i olika familjeterapeutiska metoder. Uppsatsen bygger på intervjuer med sex erfarna familjeterapeuter med olika inriktning som besvarar generella frågeställningar samt beskriver hur de skulle arbeta med ett kliniskt exempel.Resultatet visar att familjeterapeuterna, oavsett tidigare kännedom om begreppen tänker likartat kring mentalisering och reflektiv funktion i sitt kliniska arbete, och att alla utom en terapeut väljer snarlika förhållningssätt i arbetet med det kliniska exemplet. Slutsatsen är att mentalisering/reflektiv funktion är något som familjeterapeuterna ser som vägen till att skapa förändring och att familjeterapeutiska metoder kan användas för att arbeta med och förstärka mentalisering och reflektiv funktion.The purpose with this essay was to examine and describe how to work mentalizing and enhancing the reflective function with various family-therapeutic methods. The essay consists of interviews with six experienced family therapists with various orientations who answers general questions and describes how they would work with a clinical example.The essay concludes that the family therapists, regardless of previous knowledge of these concepts, think alike about mentalizing and reflective function in their clinical work. All except one also choose a similar approach in their work with the clinical example.
Arbetsterapeuters kliniska resonemang vid bedömning av arbetsförmåga hos personer med neuropsykiatriska funktionsnedsättningar. : En kvalitativ intervjustudie
Uppsatsens syfte var att beskriva hur arbetsterapeuter resonerar kliniskt vid bedömning av arbetsförmåga hos personer med neuropsykiatriska funktionsnedsättningar. För denna studie användes en kvalitativ ansats. Semistrukturerade intervjuer genomfördes med fem arbetsterapeuter som jobbar mot arbetsmarknaden. Frågeområdena inspirerades av clinical reasoning ?three track mind? där procedural, interactive och conditional reasoning utgör de tre olika tankemönstren.Resultatet redovisades i fyra kategorier och ett övergripande tema som beskriver arbetsterapeuternas kliniska resonemang: Att forma en frågeställning, Att välja bedömningsmetod, Att utforma en slutrapport och Yrkeskompetens.
Prevalens av osteochondros hos avkommor efter svenska halvblodshingstar : en retrospektiv tvärsnittstudie utförd med hjälp av rutinmässigt insamlade klinikdata från röntgade hästar vid ett svenskt djursjukhus
The main purpose of this study was to study the heredity of osteochondrosis (OC) in fetlock-, hock- or stifle joints within the Swedish half-bred population, using data from the regional animal hospital in Helsingborg.
A large number of horses with clinical symptoms, for example lameness, are radiographed every year at the regional animal hospital in Helsingborg. In addition, many clinically healthy horses are radiographed in order to be sold (inspection radiographed / export radiographed). This study is based on electronically stored data from horses in both of these groups of patients that underwent joint radiography at the regional hospital in Helsingborg during the years 1992-1999. The first file (inspection file) contained 1035 observations from 983 horses that had their fetlock-, hock - or stifle joints radiographed for inspection or export. The other file (clinical file) contained 6121 observations from 3800 horses that were radiographed due to clinical symptoms in the fetlock-, stifle or hock joints.
Hydroperikard hos katt : patofysiologi, diagnos och behandling
Hydropericardium or pericardial effusion (PE) is the accumulation of fluid in the pericardial sac and is often secondary to pericardial diseases or diseases related to the heart. It is unusual with clinically relevant pericardial diseases in cats but pericardial effusion is the most common one.
Since PE causes serious symptoms and may lead to death it is important with a quick diagnosis and treatment. PE can be acute and cause cardiac tamponade, which gives severe clinical signs. Cardiac tamponade needs to be treated immediately or else the cat will die from cardiogenic chock. More common is chronic PE where the fluid accumulates during a longer period of time and the pericardial sac stretches.
Objektiv rörelseanalys : ett stöd vid den visuella bedömningen av hälta hos hund?
Lame dogs are a common group of patients for the practicing veterinarian. In the
literature it is described how a clinical examination can be performed, based on
general clinical-, orthopedic- and neurological examination, and visual evaluation
of the dog when standing and during motion. For research, objective gait analysis
systems are also used to study clinically healthy and lame dogs during motion.
The aim of this degree project was to compare objective kinematic gait analysis
with a visual evaluation of dogs with different types of lameness. The project was
a pilot study to show if objective gait analysis could be used as a support for the
visual examination.
Ten lame dogs of different breeds and with different diagnoses were included in
the study. They were all patients at the University Animal hospital, Uppsala.
Malassezia otit hos hund : utvärdering av lokal behandling med betametason, ekonazol respektive ättiks- och borsyrelösning
Malassezia otitis in dogs is a common cause of visit to a veterinary service. In otitis externa due to Malassezia overgrowth the dog has a higher number of yeast organisms and/or a local inflammatory response to the micro organism. Common clinical signs include pruritus, erythema, swelling and increased exudate production. Clinical symptoms and results from cytology of ear swabs from the ear canal is the mainstay for diagnosis. Any underlying condition has to be identified and corrected to avoid relapse.
The treatment options for infective otitis externa are based upon topical administration of eardrops containing antibiotics, steroids and antifungals.
Islandshästar med hosta och/eller prestationsnedsättning : skiljer de sig åt jämfört med andra raser?
The purpose of the study was to investigate whether or not Icelandic horses are
less severely affected in clinical symptoms of cough or decreased performance
than other breeds of horses. A breed variation in chronic respiratory disease
severity was suspected based on clinical experience at the Institution for surgery &
medicine, large animal, SLU Uppsala. A retrospective journal study of 17
Icelandic horses and 17 Swedish Standardbred horses with chronic problems with
cough and/or decreased performance compared several measurements of disease
severity.
The clinical signs, physical examination and laboratory testing results compared
were respiratory rate, abdominal breathing, lung auscultation, endoscopy results,
broncho-alveolar lavage (BAL) results and the blood gases pO2 and pCO2. All
parameters were available for all 34 individuals except for the blood gases, which
were analysed, in only four Icelandic horses and four Swedish Standardbred
horses.
The only parameters that appeared different between the two groups were
respiratory rate and pO2. The four Icelandic horses, which had blood gases
analysed, had more severe hypoxemia.