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8339 Uppsatser om Clinical research - Sida 2 av 556

Lokalisationen av osteochondrosförändringar hos svenska halvblodshästar :

The aetiology of osteochondrosis (OC) is known to be complex and multifactorial. The occurrence of bone fragments in joints and their connection to osteochondral disease are no exception. In the hock and stifle joint of the horse this type of lesion has generally been considered to be of osteochondral origin, while the process behind these fragments in the fetlock joint has been up for discussion. The objective of this study was to determine the frequency and the localisation of OC in Swedish warmblooded horses. In order to do so all radiographs of stifle, hock and fetlock joints performed on Swedish warmblooded horses during the period of 1992-1999 at Regiondjursjukhuset in Helsingborg were examined and the material was divided into two groups.

Clinical Innovation Fellowships : Uppföljning av en ny metod för förändringsarbete inom sjukvården

Centrum för Teknik i Medicin och Hälsa (CTMH) har, i samarbete med Stanford University, utvecklat programmet Clinical Innovation Fellowships (CIF) för att identifiera förändringsbehov inom vården. Syftet med den här uppsatsen är att undersöka huruvida arbetssättet med Clinical Innovation Fellowships har åstadkommit förändringar för patienter, medarbetare och ekonomi på värdklinikerna.Undersökningen har visat att arbetssättet med CIF framförallt har åstadkommit förändringar för medarbetare. Även förändringar för patienter har genomförts, dock har den ekonomiska aspekten av programmet varit svårare att mäta och se några konkreta förändringar inom.Det har gått att tyda en generell trend som visar att de undersökta värdklinikerna valt att börja med de förändringar som är av mer praktisk natur och enklare att genomföra lokalt på kliniken. Värdklinikerna har haft svårare att genomföra större, organisatoriska förändringar, vilka styrs mer centralt på sjukhusen. Undersökningen på de utvalda värdklinikerna visade att något som skulle gynna CTMHs arbetssätt med CIF skulle vara att etablera en uppföljning på klinikerna.

Escherichia coli-mastitis in dairy cows :

Escherichia (E) coli is one of the most common udder pathogens associated with acute clinical mastitis in Swedish dairy cows. The aim of this study is to review some of the existing literature on E coli mastitis from a Swedish perspective. The bacteria, its most important characteristics, and diagnostics under field conditions is covered, as well as what happens during infection, how E coli affects the cow and which consequences this have. Clinical symptoms associated with E coli mastitis are described and information on when these cases of mastitis usually occurs is given. Risk factors in the cow?s enviroment are described as well as the importance of the cow?s immune defence.

Orala hälsorelaterade livskvalitetsinstrument som har använts på äldre individer ? en litteraturstudie

Aim: Through the review of scientific articles, this study aimed to identify which oral health-related quality of life instruments that have been used in studies to measure the oral health-related quality of life in older individuals and the application of such instruments.Method: The study is based on a systematic literature review, where 14 articles have been chosen and evaluated against a checklist. Result: The oral health-related quality of life instruments that have been used on individuals, 65 years and older, are OHIP-49, OHIP-14, OHIP-20 or OHIP-EDENT, GOHAI and OIDP. The instruments are used to examine factors associated with the oral health-related quality of life. Significant associations have been identified, among other things, between the number of teeth in static occlusion, dry mouth and the quality of the dentures, and oral health-related quality of life. Social and cultural associations have also been revealed.Conclusions: Today there exist several well functioning instruments that are used for research purposes.

Orala hälsorelaterade livskvalitetsinstrument som har använts på äldre individer ? en litteraturstudie

Aim: Through the review of scientific articles, this study aimed to identify which oral health-related quality of life instruments that have been used in studies to measure the oral health-related quality of life in older individuals and the application of such instruments. Method: The study is based on a systematic literature review, where 14 articles have been chosen and evaluated against a checklist. Result: The oral health-related quality of life instruments that have been used on individuals, 65 years and older, are OHIP-49, OHIP-14, OHIP-20 or OHIP-EDENT, GOHAI and OIDP. The instruments are used to examine factors associated with the oral health-related quality of life. Significant associations have been identified, among other things, between the number of teeth in static occlusion, dry mouth and the quality of the dentures, and oral health-related quality of life. Social and cultural associations have also been revealed. Conclusions: Today there exist several well functioning instruments that are used for research purposes.

Utvärdering av Komm-A, en modell för arbete med kommunikationsbok för personer med afasi i logopedisk verksamhet

The purpose of this study was to evaluate Komm-A, a model for usingcommunication books in clinical practice for people with aphasia. The studyconsisted of two group studies and one case study. One of the group studies had apretest-posttest design and consisted of nine couples; a person with aphasia andhis/her communication partner. The material used was Quality of communicationlife scale (QCL), Communicative effectiveness index (CETI), Goal attainmentscaling (GAS), and a questionnaire to the communication partner. The other groupstudy consisted of seven speech-language pathologists who worked with thecouples according to the Komm-A model.

Utveckling av metod för utvärdering av synnervens funktion hos häst :

VEP, visual evoked potential is an electrophysiologic test that can be used for evaluating the higher visual pathways. The aim of this study was to investigate if it is possible to adapt this method to horses. This method could have a clinical use in addition to the existing diagnostic methods that are available to evaluate vision in horses. Firstly, this study contains a summary of relevant studies done on animals and, secondly, an experimental part where the possibility of recording VEP in nonsedated and sedated horses is investigated and where to position the recording electrode to obtain the best results. Our results show that it is possible to record VEP in horses in a clinical setting. VEP was best recorded in the sedated horse to avoid movement artifacts and other disturbances.

Hypoadrenokorticism hos storpudel :

Hypoadrenocorticism (Addison´s disease) results from insufficient production of glucocorticoid and mineralcorticoid hormones from the adrenal glands. The disease is often difficult to diagnose in an early stage because of the multitude of associated vague clinical signs. The standard poodle is one breed presupposed to be at higher risk of developing the disease. The purpose of this study was to give a review of canine hypoadrenocorticism as described in literature, and to characterise Addison´s disease in a population of standard poodles in Sweden. Statistics on incidenceproportions by breed for hypoadrenocorticism from the database of the Swedish insurance company Agria are presented.

Insättningsrutinernas effekt på tillväxt samt effekten av klinisk sjukdom på ätbeteendet hos kalvar i gruppbox med automatisk mjölkutfodring :

The aim of the present study was to investigate the effect of strategy for grouping calves into group pens with automatic milk-feeding systems on the calves' health and growth rate. The usefulness of changes in feeding behavior recorded by the computerized milk-feeder during periods of illness to identify calves with clinical diease was also studied. In the first experiment, 64 calves were moved in and out of group pens in a continuous way, while 46 calves were transferred into group pens until the the pen was considered "full". The calves in the latter groups were then held together until weaning. It was found that calves in the fixed groups grew approximately 100 g / day more compared to the calves in the dynamic groups. Signs of clinical respiratory disease were less frequent in this group, while the incidence of diarrhoea was slightly higher. In the second experiment health parameters, milk consumption and feeding behaviour was recorded daily for 46 calves.

Uppnår sjuksköterskestudenter lärandemålen?

Objective: To see if nursing students believe that they have acquired the knowledge that the Higher Education Ordinance demand and if there is any difference between the theory learned at the University and the clinical reality in which students receive their practical training. Method: The method is quantitative and is divided into two parts, one in which the authors describe how the questionnaire was developed and how validity was strengthened. In the second part, the authors describe how the data analysis was made and how reliability of the result was strengthened. Result: The result shows that the students felt that they have achieved most of the objectives of learning demanded by the Higher Education Ordinance. But some objectives are perceived as not at all or only partly achieved.

Utvärdering av en snabbtest för diagnostisering av hypokalcemi hos nötkreatur :

Clinical signs of hypocalcaemia in dairy cows are easily recognized, and a rapid response to treatment generally confirms the diagnosis in the field. However, clinical signs of other disorders in cows, such as toxemia, calving paralysis, or muscoskeletal injury, may mimic those associated with hypocalcaemia. Therefore, making a diagnosis of hypocalcaemia on the basis of clinical signs alone may be difficult. In ambulatory veterinary practices, cow-side tests are useful to make the diagnosis and prognosis easier. Kruuse?s Kalcium Test is a cow-side test based on the principle that calcium ions are necessary for coagulation of blood, and that chelation with EDTA prevent coagulation.

Impact of hygiene training on dairy cows in northeast India : en hygientränings påverkan på mjölkkor i nordöstra Indien

Mastitis in dairy cows is an emerging and challenging disease in the tropics, including India. Nation-wide reports suggest that the incidence of clinical mastitis varies from 3.94% to 23.25%, and for subclinical mastitis from 15.78% to 81.60%. In Assam, a northeastern province of India, dairy is an essential part of the mixed farming system that exists in the state, but the milk yield is far below domestic standards. In 2009-2010, International Livestock Research Institute (ILRI) and local associates started to develop a training program for local farmers in Assam, in order to enhance the informal bovine dairy sector in and around Guwahati, India. The project continued until mid-2013.

The RECK gene and invasive cancer development : the significance of RECK in angiogenesis and inhibition of matrix metalloproteinases

The RECK gene is a relatively new discovered gene with important implications for cancer research. The research has been primarily concentrated on the human gene with the ultimate aim to identify the invasive characteristics. Up regulated RECK is linked to significantly prolonged survival rates in patients with severe forms of malignancies. RECK is normally expressed in all cells of the body and has an important role in the balance between destructive and constructive features of the extracellular matrix. The RECK protein is a membrane-bound glycoprotein that inhibit matrix metalloproteinases which has the function of breaking down the ECM. There is a significant correlation between RECK gene expression and the formation of new vessels, presumably via the mediation of VEGF which is an important and powerful inducer of angiogenesis.

Höftledsdysplasi och armbågsledsartros hos labrador retriever med känt radiologiskt status av höftleder och armbågar : en tredje uppföljande studie

Joint-related diseases including hip dysplasia (HD) and elbow arthritis (ED) can in advance cases lead to that the dog has to be put down, and these diseases are also the cause to expensive veterinary treatments of many large breeds, including Labrador Retrievers. The aim of this study was to make a follow-up study on the 271 Labradors, who previously participated in a study on the effect of nutrition and exercise on hip and elbow status in a birth cohort born year 2000. That study investigated the relationship between nutrition, exercise, and HD and ED. A follow up study on the same dogs at 5-6 years of age investigated the clinical effects of the radiological hip and elbow status at 1 years of age and if was effected by body condition score. This study took place in 2011-2012 and 187 Labrador retrievers participated.

Sjuksköterskors upplevelse av att arbeta på en akutsjukvårdsavdelning

Background: Previous research demonstrates that negative stress in the current situation is common among nurses working in emergency care. The stress is demonstrated to be associated with poorer provided care for patients and impaired health of nurses. Aim: The purpose of the study was to highlight nurses' perception of stress and their work for a good nursing care on an emergency care department. Method: An empirical design with qualitative approach has been used. Five semi-structured interviews were conducted with nurses and forms the basis of the results of the study.

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