Idiopathic pulmonary fibrosis (IPF) is a chronic respiratory disease with an estimated incidence of 3-6 cases per 100 000 inhabitants in Sweden. There is no cure for the disease, which inevitably leads to death. A similar disease has been found among terrier dogs, with an especially high prevalence in the West Highland White Terrier (WHWT). Dogs with pulmonary fibrosis become lethargic with exercise intolerance, and in some cases they develop cough and respiratory distress. This thesis gives a brief review of the field of pulmonary fibrosis and presents a method for analyzing surfactant proteins in bronchoalveolar lavage (BAL) in the dog.

Objective: The aim of this study was to compare equations used to calculate BMR to values of BMR obtained from measurements in order to determine the most suitable equation to be used on children and adolescents with CF.Design: The participants where children and adolescents with CF. Data was collected from the division of Clinical Nutrition at Uppsala Akademiska Sjukhus. Age, weight, height, BMI, BMR, FFM and FM was recorded from 27 measurements. BMR from the participants collected from the indirect respiratory calorimetry was compared to the results obtained from five equations used to obtain a calculated value of BMR.Results: Tverskayas equation was best correlated with the measured BMR for the whole group. The equation underestimated BMR for the participants with a measured BMR over 1400 kcal/24h and overestimated BMR for participants with a measured BMR under 1400 kcal/24h.

The study aimed to evaluate picture communication during clinical as-sessment and intervention procedures in paediatric care. As part of the project KomHIT (Augmentative communication in paediatric health care settings) care professionals at different care units were provided with education and designed pictorial supports. These consisted of appointment letters with pictorial support, visual schedules and communication boards with both general and specific vocabulary. Care professionals and parents to children with and without communication disabilities participated. Survey data from care professionals and parents at five care units was supplemented with qualitative data from an interview with a multiprofessional group at one of the care units.

Can degree of degenerative brain disease be predicted with the help of measurements of cognitive deterioration?Alzheimer?s disease progresses through nerve cell break down in the brain and the simultaneous deterioration of the individual?s cognitive function. This disease is common among elderly persons. This thesis examines if the level of deterioration of cognitive function is associated with different biochemical and clinical markers for degenerative brain diseases. In addition, this thesis examines if the level of decline in cognitive functions vary between groups with different levels of degenerative brain disease.

The WT1 gene is a complex gene originally known to suppress cancer in kidneys. Studies of WT1 knockout mice have confirmed the important role of WT1 in the pathogenesis of Wilms? tumour, a tumour which counts for 95% of all childhood renal tumours. In that case the WT1 gene acts as a tumour suppressor gene. Subsequent research has shown that the WT1 gene in many other cases acts as an oncogene, e g in leukemia or lung cancer (even though these cancer forms can emerge as a result of many other aetiological factors).

The parasite Neospora caninum is an intracellular protozoa discovered in the late 1980s. N. caninum has an indirect lifecycle which means it needs a definitive host and an intermediate host. The confirmed definitive host for N. caninum is dog and the intermediate hosts are among others dog and cattle.

The parasite Neospora caninum is an intracellular protozoa discovered in the late 1980s. N. caninum has an indirect lifecycle which means it needs a definitive host and an intermediate host. The confirmed definitive host for N. caninum is dog and the intermediate hosts are among others dog and cattle.

The concentration of acute phase proteins in serum is altered as a response to inflammation, infection or trauma. this makes these proteins potential biomarkers of unspecific pathological processes. In cattle, haptoglobin and serum amyloid A are the two acute phase proteins that show the largest increase in serum concentration as a result of inflammatory processes. The haptoglobin concentration has been shown to correlate to clinical signs as well as inflammatory processes found at post mortem examination. This feature could be useful prognosis of the individual as well as for monitoring the health status of a herd or identifying carcasses that shold be examined closer at the slaughter-house.

The purpose with this study is to examine what kind of support there is for school libraries at the selected independent upper secondary schools and how these schools ensure that libraryservices is available to their students and their teachers. The purpose is also to examine what attitudes the administrators of the schools have to school libraries and teaching in information seeking. A qualitative method with interviews was used to fulfil the purpose. As a theoretical basis of the study Loertschers taxonomies of the school library media program and Limbergs three levels of pedagogic research were used and the interviews were analysed with these two theoretical frameworks as a background. The result of the study showed that neither one of the three examinated schools has a school library which means that they use the public library instead.

This study examined the psychological processes of autonomic arousal and distress, erroneous beliefs about sleep, worry about sleep, selective attention and monitoring and safety behaviours related to sleep, on the subject of daytime impairments associated with insomnia. The psychological processes were evaluated against as follows: sleep measures, anxiety, depression, medical disease and the use of medications. The measure daytime impairments complied with the established research diagnostic criteria. A correlation analysis indicated that psychological process, anxiety, depression and one of the sleep measures are associated with daytime impairments. The results of a multiple regression analysis proved that only erroneous beliefs about sleep, worry about sleep and safety behaviours related to sleep are linked to daytime impairments associated with insomnia.

Effektiviteten av manualiserad Motivational Interviewing prövades i en experimentell design. Gymnasieelever med hög frånvaro (n=89) blockrandomiserades till antingen två sessioner Motivational Interviewing eller någon av de två kontrollgrupperna, som erhöll validerande samtal respektive ingen intervention. Den beroende variabeln utgjordes av förändring i frånvaro som rapporterades av de deltagande skolorna. Utöver detta användes School Refusal Assessment Scale för att undersöka orsaker till frånvaron. University of Rhode Island Change Assessment användes för att mäta motivation enligt Prochaska och DiClementes förändringsmodell.

The aim of the study was to describe how hygienist`s receiving their certificate during 2003 and 2004, perceive their working situation, salary and impression of their first employment as a registered dental hygienist. A questionnaire was sent out to new dental hygienist`s examined year 2003 and 2004 in Sweden. Most of the new examined dental hygienist`s found the education adequate or more than adequate. A few individuals found it inadequate. The ones finding the education inadequate wanted more clinical practice and more training in administrative work.

1. Reaction on burial depth and nitrogen availability and placement in competition with a crop In this trial it was investigated how couch grass (Elymus repens) changes its ability to compete in stands of wheat and barley with different burial depth and different amounts and placement of nitrogen. More knowledge in this area can be valuable in the attempt to decrease the use of herbicides and still keep the weeds under control. The trial was carried out in the summer of 2004 as an outdoor pot experiment. The pots contained 15 litres of soil with a surface of 0,06 m2.

Background: Anxiety with children before surgery is well known. From the 1950s there are various assessment instruments. Despite that most day surgery units offer preparation for children and parents, there are many children who exhibit a strong anxiety the day of surgery, which can lead to postoperative behavioral changes. Today the nurse estimates the anxiety of a child on personal experience and knowledge, forming the basis for estimation whether the child is in need of sedation or not. The purpose: of this study was to evaluate instruments that the nurse can use in measuring the degree of anxiety of children before fast clinical settings, such as day surgery.

Det saknas studier hur handledarna upplever handledning på avancerad nivå inom psykiatrisk omvårdnad. Rollen handledarna har är komplex, de ska både fungera som en mentor och som den som bedömer studenternas prestationer samt ge god vård åt patienten. Syftet med denna studie är att belysa hur handledning upplevs av den handledande sjuksköterskan under Verksamhetsförlagd utbildning (VFU) för specialistsjuksköterskor i psykiatri. Att få kunskapen studien genererar skapar förutsättningar för organisationen och universitetet att anpassa utbildning och återkoppling som gynnar handledarna och studenternas utveckling samt höjer vårdkvaliteten för patienterna. En explorativ kvalitativ ansats enligt fokusgruppsintervjuer har ansetts lämplig för studien då målet är att fånga vidden och komplexiteten i handledning.