Malt lymphoma is a malignant disease that can arise in a variety of extra nodal sites. Previous studies indicate that tumour arise from more mature B-cells.Our purpose was to examine the presence of clonality and somatic hypermutation of immunoglobulin (IgV?) of MALT lymphomas.Paraffin-embedded tumour samples from13 MALT lymphoma were subjected to rearrangement analysis, by using PCR, heteroduplex gels and sequence analysis.Successful amplification was seen in 10/13 cases and sequences of IgV? genes were obtained in 6/13, all of them were mutated. The percentage of mutation compared to germline sequences was 1,1% to 8,6% monoclonal rearrangemang. It was demonstrated that 5 of 7 clones were derived from the V?3 family, 2 from V?1 and 1 from the V? 4 family..

Understensho?jden is Stockholm's largest eco-village which was built in the early 1990s with the vision of enabling ecological living for people. However the ecovillage is no longer considered as environmentally friendly because of its relatively high energy consumption, and non-updated energy system. The purpose of this study is therefore to investigate how Understensho?jden should reduce their energy consumption and upgrade its energy system by using Blower-Door, IR-camera and Design Builder.

Idiopathic pulmonary fibrosis (IPF) is a chronic respiratory disease with an estimated incidence of 3-6 cases per 100 000 inhabitants in Sweden. There is no cure for the disease, which inevitably leads to death. A similar disease has been found among terrier dogs, with an especially high prevalence in the West Highland White Terrier (WHWT). Dogs with pulmonary fibrosis become lethargic with exercise intolerance, and in some cases they develop cough and respiratory distress. This thesis gives a brief review of the field of pulmonary fibrosis and presents a method for analyzing surfactant proteins in bronchoalveolar lavage (BAL) in the dog.

Understensho?jden is Stockholm's largest eco-village which was built in the early 1990s with the vision of enabling ecological living for people. However the ecovillage is no longer considered as environmentally friendly because of its relatively high energy consumption, and non-updated energy system. The purpose of this study is therefore to investigate how Understensho?jden should reduce their energy consumption and upgrade its energy system by using Blower-Door, IR-camera and Design Builder.

Bovine viral diarrhoea virus (BVDV) is the causative agent of a complex of disease syndromes in cattle with high economical and welfare impacts. BVDV occurs as two biotypes; cytopathic (BVDVcp) and noncytopathic (BVDVncp) determined by differential effects on cultured cells and can also be divided into two genotypes (BVDV1 and BVDV2) on the basis of genomic diversity. The interaction between BVDV and the host?s immune system is regarded a key aspect in the sequel of BVDV infection. Infection with BVDV normally causes an acute transient infection, with mild to subclinical signs, but occasionally results in severe and even fatal disease.

Denna rapport bygger på den kommande solcellsfasaden på kvarteret Frodeparken i centrala Uppsala. Projektet genomförs genom ett partneringavtal mellan Skanska Sverige AB och Uppsalahem. Syftet med detta examensarbete var att skapa en underhållsplan samt en investeringskalkyl för projektet. En teknisk bakgrund för solcellsanläggningar har sammanställts för att förstå hur systemet fungerar. Underhållsplanen grundas på fakta från solcellsleverantören och uppgifter från referensobjekt. Det har visat sig att solcellsanläggningar kräver väldigt lite underhåll. För att få en bred syn på investeringen har ett antal simuleringar på investeringskalkylen genomförts.

In the middle of Australia there is a city called Alice Springs. The city has one of the highest amounts of daily sunshine hours and sun irradiation in the world. The Australian Government runs a project called Solar Cities, and Alice Springs is one of the participators. The main part of the goal with the Solar Cities project is to increase the amount of electricity generated by solar power and by doing that lower the impact on the environment. This thesis examines the possibilities for construction of a large scale solar power plant in Alice Springs. This is done to determine the potential of creating a more sustainable energy system in the city.

The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

In the middle of Australia there is a city called Alice Springs. The city has one of the highest amounts of daily sunshine hours and sun irradiation in the world. The Australian Government runs a project called Solar Cities, and Alice Springs is one of the participators. The main part of the goal with the Solar Cities project is to increase the amount of electricity generated by solar power and by doing that lower the impact on the environment. This thesis examines the possibilities for construction of a large scale solar power plant in Alice Springs. This is done to determine the potential of creating a more sustainable energy system in the city.

Denna rapport kommer att redogöra för NK-cellers (Naturliga mördarceller) beteende vid odopat tillstånd. Det vi kallar dopning är när NK-celler aktiveras genom interleukin-2, detta är en signalerande molekyl i vårt immunsystem som reglerar aktiviteten hos vita blodkroppar vilka utgör en del av immunförsvaret.Med hjälp av ett par mikroskopfilmer har vi kunnat följa varje enskild NK-cells migration(rörelse) och interaktion med våra målceller i ett prov under en 8-timmars period. De målceller vi använder är en sorts tumörceller, HEK 293T(Human embryonic kidney 293T cells. Vi har valt att spåra cellerna manuellt med ett program kallat ImageJ och automatiskt med ett matlabprogram, Baxter algorithm. Anledningen till att vi dessutom valt att spåra automatiskt är för att kunna avgöra hur väl detta program kan spåra celler.

This report is a thesis on requests from Sandvik Mining and Construction (SMC) in autumn of 2012. The goal of this work was to study the feasibility of creating and implementing an Equalized preventive maintenance program in SMC maintenance operations and reduce downtime for preventive maintenance (PM). To investigate whether this was possible, the authors studied the current procedures for the PM. The authors have collected and analyzed all relevant information within the maintenance department reporting system as well as through interviews determined whether it is practical to introduce a Equalized PM programs. The authors had also studied the possibilities to entrust part of the maintenance work to the operators of the machine cells.

Lactobacillus reuteri has been used as probiotics in piglet and chicken feedings as well as in different diary products for humans. In this EEF-work I have shown that L. reuteri can be an alternative for treatment of vaginitis in laboratory rats used for breeding. In a breeding stock with 3000 animals some animals had a vaginal infection with ??haemolytic streptococci group G.

Fibroblast growth factors are signaling peptides that controls important cellular processes such as proliferation, differentiation, migration, adhesion and survival. Through binding to different types of receptors on the cell surface, these peptides can have different effect on the target cell. Which effect that is achieved depends on many factors. Thus, each of the 24 known FGFs different biological responses. The FGF receptors (FGFR 1-4) initiates different intracellular pathways which in turn leads to different biological responses.

This master thesis was a subtask of a project called EMIR-1. The goal with the thesis was tobuild a system for particulate mass measurements in one of the engine test cells at KTH. Theparticulate mass measurements are planned to be measured with a TEOM.The exhaust gases must first be diluted with air before the sample is sent to the TEOM.Therefore an ejector diluter for this matter also was designed and evaluated in the thesis.Emissions measurements have been done both with and without dilution to determine thedilution ratio. Tests have been done for different speeds and loads.Problems with stability of the dilution ratio have been an issue throughout the process andpressure pulsations in the exhaust pipe are believed to be the cause. More tests have to be done tomake sure that this is the problem.One idea is to make the inner diameter of the diluter nozzle smaller and see if it changes thedilution ratio stability.

The vertical electronic excitation energies for the narrow-bandgap polymers LBPF, EP37 and EP62 have been calculated using Density Functional Theory (DFT). Also the vertical excitation energies for the acceptor unit of LBPF have been calculated using the Hartree-Fock (HF), DFT and Coupled Cluster (CC) methods. The calculations cover the visible and infrared wave length region and two strong transitions are obtained, one corresponding to the pi to pi* transition and one corresponding to the pi to Acceptor transition. The excitation energies obtained from DFT are below the corresponding experimental results and attempts have therefore been made to perform bench-marking calculations using a hierarchy of CC methods..