Background: Many authors consider knowledge to be a significant source for competitive advantage. Replicating companies found their competitiveness on an ability to leverage its knowledge base by replicating its business model in new contexts, a process often referred to as the McDonalds approach. Several authors emphasize that an efficient method for knowledge transfer may increase the risk for imitation. Purpose: The purpose of this study is to examine in an explorative manner how strategies for replicating complex knowledge systems are employed and developed. Furthermore, our ambition is to explore the notion of Replication strategy.

Background: Hepatitis E (HEV) is a small, non-enveloped virus that belongs to the viral genus Hepevirus. HEV is a positive sense single-stranded RNA virus and there is insufficient information regarding its Replication. This is mainly because the virus has low capacity to grow in normally used cell cultures. Many specific strand assay detection studies have been done in order to understand more about HEV Replication. Unfortunately, these assays have the disadvantage of giving false positive results.Aim: The aim of this project was to improve the positive strand assay to increase specificity and eliminate false positivity which is due to high sensitivity of the polymerase chain reaction (PCR).

AbstractA systematic Replication study was conducted at the training site at the University of Karlstad. Student therapists performed cognitive-behavioural therapy (CBT) as a part of their master?s degree in psychology.  The systematic Replication that took place was based on the work of Hiltunen et al. (2013), who evaluated the efficacy of CBT treatment conducted at the training site previously mentioned.

Den här studien genomfördes i Helsingborgs kommun som ett examensarbete inom livsmedelstillsynsprogrammet på Lantbruksuniversitet (SLU) i Uppsala. Idén med uppsatsen uppkom efter att författaren deltagit i ett möte på miljökontoret i Helsingborg. En kontroll som gjorts bland livsmedelsbutiker i kommunen visade att 60 % av livsmedelsbutikerna fick underkänt vid inspektioner. De områden som fick flest anmärkningar var rengöring och underhåll av lokaler och utrustning, internrevision och temperaturer i kylar och frysar. Över hälften av butikerna fick underkänt vid kontrollen vilket visar på att det uppenbarligen finns brister i egenkontrollen.

Denna rapport återger arbetsprocessen kring att utvärdera datalagringsstruktur och förbättra prestanda för generering av parameterfiler för kortterminaler. Arbetet utfördes på plats hos Esplanad AB, ett företag som bland annat arbetar med säkerhetslösningar och distribution av inställningar för betalstationer.Uppgiften bestod av att utvärdera möjligheter till att förbättra databasen som sparar alla inställningarna för betalsystemen, samt att förbättra kodstruktur och prestanda för programmet som genererar filerna.Rapporten beskriver testning av prestanda, både på Esplanads gamla program för att generera parameterfiler och det nya som konstruerades. En lösning presenteras som inkluderar förbättring av filgenereringens prestanda och en ny struktur på databasen för ökad skalbarhet.Tester visar att det nya systemet klarar av att skapa parameterfiler på TLV-format ungefär 16 gånger snabbare. Den föreslagna lösningen implementerar parallella processer och replikering av databasen..

Franchise theorists have to a large extent failed to keep up with the actual development in global franchise chains. The recent emergence of fast growing multi-unit-franchisees has fundamentally been ignored, and it has been claimed that the new phenomenon can be regarded as a mere Replication of the franchisors? structure and control system into sub hierarchies. This study however, suggests that the reality is more complex. Through conducting case studies of two Nordic multi-unit-franchisees, new theories are built explaining how and why control systems are designed the way they are.

In this study I?ve used qualitative interviews to examine four male preschool teachers? interpretations of gender and their work with gender in preschool. Specifically, I?ve been interested in what thoughts male teachers have about the preschool gender assignment, how they express these thoughts in their work, and how they perceive their role as men in preschool in relation to gender and gender equality. The teachers express that the preschool gender assignment means that one should treat girls and boys equally and give them the same opportunities.

Background and problem: The importance of banks was clearly shown during the last financial crises, when the crises that started in the banking sector spread to the rest of the world. This is one of the reasons that this thesis is focused on banks in particular, one other reason is that a lot of previous studies has chosen to exclude banks because of the fact that their balance sheet differ from non-financial companies. This thesis is a beginning in filling in the gap that exists in the knowledge of banks capital structure. Purpose: The purpose of this thesis is to prove that it is possible to explain the capital structure in banks and that differences in the capital structure of the banks in Great Britain, Sweden and the United states of America exists. Method: The fact that our study is partly a Replication of two earlier studies made a deductive approach most appropriate.

Completed durability testing of gearshift gaiters at Kongsberg Automotive in Mullsjö, is sometimes leading to discussions regarding whether or not a gaiter is supposed to be a pass or a fail. That is because the current pass/fail-criterion are a bit vague. A durability test takes around 4-5 weeks to complete which is a long time if the tested material does not pass the test and a new material has to be tested instead. Stricter pass/fail-criterions and a faster testing method for the materials are therefore desired.In order to develop a durable pass/fail criteria, seven already judged gaiters were chosen. Every one of the gaiters was put through detailed analysis, after which there were a new assessment of the gaiters.

Relationships between defence mechanisms and body movements were investigated in regard to three hypothesis; I. that a difference in frequency of body movements correlates to different signs of defence mechanisms, II. that themes of body movements can be identified in regard to signs of defence mechanisms, III. that no significant differences will be found between the different groups of gender. The aim of the study was to seek a relation between quasicommunicative body movements and defence mechanisms.

Vectors based on lentivirus backbones have revolutionized our ability to transfer genesinto many cell types. Lentiviral vectors integrate into the chromatin of target cells and do not transfer any viral genes causing vector Replication. Both of these features arecommonly used in gene therapy and have been used clinically in individuals sufferingfrom cancer, infections and genetic diseases. It has been discovered that T-cells can be genetically modified to be used as effective weapons against cancer: therefore virus mustbe produced to deliver the gene of interest into the T-cells. In this project, lentiviralvectors have been produced to transfer the gene coding for a chimeric antigen receptor(CAR) which is directed to CD19 on B-cells.

Tumour development occurs to a large extent because of dysregulation of the cell cycle. Of particular importance are defects occurring in the G1 phase. The reason why G1 is critical is because of the influence of several signals (external signals as well as cyclins and cdks) on this stage. The G1 phase can be divided into two parts, G1pm and G1ps. Each part has its ?own? restriction point which needs to be passed in order to progress to S phase.

Thymidine kinase 1 (TK1) is an intracellular enzyme involved in ?the salvage pathway? where the uncomplete parts of DNA are transformed into DNA precursors. The expression of TK1 is cell cykle specific, with the highest level during S-phase when DNA-synthesis is most active. One kind of TK1 is present in serum and an increase in TK1 activity in serum is due to either the level of DNA synthesis in the body or the number of cells dying in a state of Replication. This can be used and is used as a marker for prognosis and evaluation of treatment in human patients with leukemia and lymphoma.

The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral Replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.

The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral Replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.