Oxochlorates are anions with a partially naturally occurrence in nature but are also spread by human activities, including the paper industry. These compounds are harmful to both nature and humans, which makes it necessary to find a good way for their degradation. There are two different kinds of bacteria that can use oxochlorates as electron acceptors in their metabolism, bacteria that break down perchlorate and bacteria that break down both perchlorate and chlorate. A bacterium that can break down chlorate under anaerobic conditions is Ideonella dechloratans which holds the genes for chlorite dismutase and chlorate reductase which are enzymes for the degradation of chlorate. Gene expression and enzyme activity of chlorite dismutase are induced under anaerobic conditions, which makes it interesting to find out how this regulation functions in order to better exploit these bacteria in biological wastewater treatment.

Patienter med cardiovaskulär sjukdom kräver i många fall en livslång medicinering där följsamheten till den medicinska behandlingen ofta brister. Följden blir ett lidande för individen med ett försämrat hälsotillstånd. Sjuksköterskans ansvarsområde innefattar att förmedla evidensbaserad kunskap till sina patienter. Syftet är därför att belysa metoder till ökad följsamhet genom sjuksköterskans pedagogiska roll i samband med läkemedels behandling vid cardiovaskulär sjukdom. Vetenskapliga artiklar är sökta via databaserna Cinahl och PubMed.

Schmallenberg virus (SBV) is a novel arthropod-borne orthobunyavirus emerging in Europe in 2011 to 2012. Acute SBV infection causes diarrhoea, fever and reduced milk production in dairy cattle, but it is mainly the reproductive disorders (abortions, malformed foetuses and stillborn animals) in ruminants that have caused substantial economical losses. The prevalence of the virus outside of Europe is poorly investigated. SBV or SBV-like antibodies were detected in Mozambique in 2013, which raised interest for a similar study in Tanzania. In this study in Tanzania, blood samples were collected from 478 sheep and goats from 39 herds in 15 different villages in three districts, covering areas in the north, south and east of Tanzania. The epidemiology of the virus was investigated by tracing antibodies by ELISA and mapping of the virus by PCR was started.

The purpose of this work is to do an investigation on the customers in the pharmaceutical sector; mainly general physicians who have taken part in the education events have any impact in their prescription behaviour after the participation in the program. The settings for this study are general practitioners in the Swedish market who have taken part in the education program held by Novo Nordisk in the treatment of diabetes disease. Methodology: The methodological approach adopted for this work is quantitative; using secondary data from the internal database from the company. The analytical model is tested through statistical analysis using the data?s obtained from the databases.

The problem of separating a non-rectangular foreground image from a background image is a classical problem in image processing and analysis, known as matting or keying. A common example is a film frame where an actor is extracted from the background to later be placed on a different background. Compositing of these objects against a new background is one of the most common operations in the creation of visual effects. When the original background is of non-constant color the matting becomes an under determined problem, for which a unique solution cannot be found. This thesis describes a framework for computing mattes from images with backgrounds of non-constant color, using Bayesian statistics.

Inflammatory bowel disease (IBD) är ett samlingsnamn för en grupp inflammatoriska tarmsjukdomar och en av de vanligaste orsakerna till kroniska mag-tarmsymtom hos hund. Orsakerna till IBD är inte helt fastställda men tarmslemhinnans immunförsvar, bakterieflora, genetiska faktorer och miljöfaktorer anses vara centrala för tillståndet. En av de mest utbredda uppfattningarna är att sjukdomen uppkommer som ett resultat av bristande immunologisk tolerans som gör att immunförsvaret felaktigt går till attack mot harmlösa antigen. Syftet med den här litteraturstudien var att undersöka vilken roll Pattern recognition receptors (PRRs) har i IBD, hur tarmbarriären påverkar risken för sjukdomen, vilka förändringar av tarmfloran som setts hos IBD-hundar och hur floran påverkar sjukdomsuppkomst. Litteraturen menar att en defekt tarmbarriär är en av de nyckelfaktorer som hör ihop med IBD. Ökad permeabilitet i tarmen kan öka exponeringen, och därmed interaktion, mellan antigen och immunförsvar vilket inducerar inflammation. Oavsett om en defekt tarmbarriär uppkommer som en effekt av sjukdomen eller om det är en direkt orsak till IBD så är det troligen viktigt för att det ska bli kroniskt.

Purpose: The purpose of this study is to investigate possible links between short selling and the stock market movements using econometric test models. Methodology: A quantitative study carried out on the time series stock lending and OMX Stockholm 30 index. Information is gathered through qualitative interviews with specialists in the field of stock lending, and studies of relevant newspaper articles and reports. Theoretical approach: The theoretical frame of reference is a further consideration of supply and demand theory. The empirical study is implemented by the simple linear regression model and a vector autoregressive model (VAR).

In this thesis, three separate experiments have been performed on different aspects of the interaction between the causal agent of clubroot, Plasmodiophora brassicae, and its hosts. In the first experiment the pathotype of the P. brassicae single spore isolate, which is currently used to construct a reference genome, has been classified using the ECD bioassay. The disease severity of infected plants was scored according to two different scales and the pathotype was determined according to three previously published guidelines. The results were compared to previous published studies describing the e3 isolate. The life cycle of P. brassicae is not well understood.

Background Calprotectin is a protein expressed in the cytoplasm inside the neutrophile granulocytes. During inflammatory bowel disease (IBD), the neutrophile granulocytes are involved in a complex interaction at the inflammatory area where they die and release their content into the intestinal lumen. Therefore, calprotectin in stool is a suitable marker for diagnosis and measurement of the disease-activity in patients with IBD. The most commonly used method to detect calprotectin in stool is ELISA, but the process of manual preparation of stool samples is time-consuming.Aim The objective of the study was to evaluate an extraction method that could replace manual preparation of fecal samples and to compare different methods for measuring Calprotectin in stool using two ELISA-methods from two manufacturers and one rapidtest.Methods For extraction of calprotectin from stool samples we used sample collector tubes from Epitope Diagnostics and fecal preparation kits from Roche. Two different ELISA-kits for measuring calprotectin concentration in stool were compared.

The aim of our thesis was to describe how the connection between co-dependent relatives and the alcohol-dependent influences the family into changes in their teamwork.Our purpose was also to answer the following questions: How is it living with an alcoholic? Are there any differences in how men and women feel and behave in their relationship with an alcoholic? Are factors like cultural belonging, genre or social class important for how the co-dependent relatives feels and behaves and handle their co-dependency?To answer these questions we made twelve thematic qualitative interviews with six adult children to alcoholics and six people married to alcoholics. We compared the results of these interviews with earlier research. We also applied System Theory and Goffman's Role Theory, as well as Bourdieu´s Capital and Habitus concept.We believe that co-dependency is a family divergence that is very similar to family disease, but that a change in attitude can trigger recovery. According to the interviews many spouses stand by their alcoholic husbands and do actions that perpetuate the alcoholic dependence and thereby hold back any recovery.

The objective of this study is to understand how people with psychiatric diseases who are enrolled at a psychiatric clinic experience the recovery process and which internal motivations and external factors influence the process. The study is based on interviews with five people who have been enrolled at a psychiatric clinic. Another aim of the study is to understand how the importance of the outpatient care for the personal recovery and the improvement opportunities of the support from the rehabilitation unit that the interviewees see. The study is qualitative and abductive approach was chosen. This means that the study is based on empirical data supported by established theories.

Syftet med litteraturöversikten var att utforska hur andningsmuskelträning har studerats hos vuxna personer med KOL, stadium 1-4, avseende använda effektmått, teoretiskt perspektiv och metodologi. Detta för att få en ökad förståelse för hur andningsmuskelträning kan användas i det kliniska arbetet, samt att vid framtida forskning kunna genomföra studier av god metodologiska kvalitet som kan ge generaliserbara resultat och ökad säkerhet kring behandlingens användningsområden.Metod: Litteraturöversikten inkluderade studier som var publicerade efter att litteratursökningen till Cochrane-rapporten ?Breathing exercises för chronic obstructive pulmonary disease? stängdes (april 2012). Elva studier inkluderades från databaserna PubMed, Cinahl, Pedro, AMED, SweMed+ och PSYCInfo med sökorden: chronic obstructive pulmonary disease, breathing exercises och respiratory muscle training.Resultat: Studierna visar att andningsmuskelträning i kombination med fysisk aktivitet har ett positivt värde för personer med KOL. Detta med avseende på funktionell fysisk kapacitet, lungfunktion, hälsorelaterad livskvalitet, samt minskning av antalet exacerbationer.

Bacillus anthracis is the causative agent of anthrax, a serious and globally distributed zoonosis affecting a wide range of wild and domestic animals, invariably also humans. However, although known to humans since biblical times, much remains to be elucidated concerning the ecology and transmission of this bacterium. Of particular interest is the Bacillus anthracis spore, the uptake of which is the predominant way to contract anthrax and which is legendary for its resilience in the environment and thus crucial for persistence and spread of the disease. Hence, the aim of this study is to review the natural transmission of Bacillus anthracis and investigate potential means by which soil persisting Bacillus anthracis spores reach concentrations sufficient to infect susceptible hosts. When reviewing the literature, three different theories can be distinguished. Firstly, ?the incubator area? hypothesis suggests that favourable soil factors, possibly in association with amoebas, may constitute an environment supporting repeated spore-bacterium-spore cycling, thus increasing the local amount of spores.

Introduction: Sex and education level has demonstrated effects on health status.Osteoarthritis is a widespread disease that causes reduced health-related quality of life and isthe most common reason for total hip replacement. Osteoarthritis was ranked as the 11thhighest contributor to global disability as reported in the Global Burden of Disease 2010.Aim: The aim of this study was to explore how sex and education level together affectedhealth-related quality of life after total hip replacement. The aim was also to examine whatdimensions of EQ-5D that changed.Methods: The study is a prospective observational study with a quantitative approach. Dataconsisted of education level, obtained from Statistics Sweden (SCB) and health-relatedquality of life before and one year after total hip replacement from the Swedish HipArthroplasty Register (SHAR). Health-related quality of life was measured with astandardised instrument, the EQ-5D, and the study population consisted of 39,141 patients.Results: Womens? EQ-5D-value, before and one year after surgery, were lower in alleducational categories compared with men.

The objective of this study is to understand how people with psychiatric diseases who are enrolled at a psychiatric clinic experience the recovery process and which internal motivations and external factors influence the process. The study is based on interviews with five people who have been enrolled at a psychiatric clinic. Another aim of the study is to understand how the importance of the outpatient care for the personal recovery and the improvement opportunities of the support from the rehabilitation unit that the interviewees see. The study is qualitative and abductive approach was chosen. This means that the study is based on empirical data supported by established theories.