The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.

Introduction:A good work environment and good resources among district nurses? and general nurses? are important in the provision of good nursing care. For patient security it is also very important that resources and time are used in an appropriate way. A lot of time is spent on non-core activity, for example administration takes more and more time, which can result in feelings of stress.Aim:The aim was to describe how district nurses? and nurses? in primary care perceived their work environment, how their worktime content was distributed and if there was some connection between perceived work environment and the distribution of work time.Methods:A mapping of the content of the work was made in two parts.

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Popular Culture is inherently political and the connection between popular culture and world politics in particular is something that has been established through years of research by multiple scholars. In this essay, my aim is to analyze how American Power is represented in popular culture. This is done in context of the decline of the American led liberal hegemony and a new Multiplex world order. A world order with multiple influential actors with varying levels of power. To analyze the way popular culture portrays American power, I have used the movie Top Gun: Maverick (2022) as an example and analyzed scenes from the movie.

Webexhibits is a growing but unexplored, cultural phenomenon that indicates a new use of the Internet for cultural communication. In the essay two quantitative methods, logganalysis and websurveys, have been used to study the visitors in 5hus.nu. The purpose is to generate knowledge about webexhibits as a cultural manifestation and medium by studying the experience and actions of its visitors. To achieve the aim the paper explores the methodological questions of how to study webusers. Theories about the exhibition as a medium and the web as a virtual area of exhibits have been used to understand and interpret the results.

The wild boar (Sus scrofa) is since its recent establishment and increasing density a controversial species in Sweden. But the attitudes towards the wild boar are poorly documented so far. To improve this knowledge, a questionnaire was sent out to chosen people (n=400) connected to the management and/or land use activities. The study got 162 replies (reply frequency 40,5%) and the results show varying attitude trends among organizations and individuals, with some aspects coherent within groups and some not. Farmers and their organization showed the most negative attitudes towards wild boars, which was expected due to the practical and economic problems they suffer from this species. People involved with forestry were more positive to wild boars, probably because the species does not affect forest growth etc severely, and may even promote plant establishment by the rooting.

Since feeding fodder crops to dairy cows is a heavy and time-consuming but often disregarded line of work, this study wishes to view the different possibilities that are currently available to decrease the time to feed and apply this knowledge on an existing farm. For this purpose, four farms have been studied due to what feeding systems that are currently used and how long time the feeding required. The occurring systems are either mobile, i.e. a feed mixer operated by a tractor witch feeds the cattle via a drivable fodder table, or a stationery mixer, i.e. an electrically powered mixer which fills an automatic feeder.

In recent years, more of high stakes (National exam- NP) have been introduced in Sweden and now (2015) the government has decided that the NP in social sciences- and natural science in 6th grade is optional in order to reduce teachers' administrative burden. Based on these reforms, to have more tests in more grades and also on the decision to remove the test, the purpose of this study is to examine how teachers perceive the work of the (NP).A quantitative research was done in the form of questionnaires. The study was based on questionnaires regarding the time for working with the NP and of the intention that the NP should be a support for teachers.The result of the study is linked to school development and the constructivist theory of learning. The results show that teachers perceive work with NP takes a lot of time, where as the time for administration seems to take slightly lesser time than the time for assessing the exams. The results also indicate that teachers perceive NP as supportive, mainly in relation to the curriculum.

The purpose has been to investigate leisure-time centers actual work on children with attention deficit disorder. In addition, the study strives to make leisure-time centers way of working, in relation to their assignments, visible. The study has also compared how the leisure-time centers work and what the research says. The survey was conducted with the help of three exploratory interviews with pedagogues and three-piece observations at the leisure-time centers. It was carried out at three different schools in two counties in Sweden.The results of the survey show that the schools are trying to create clear procedures, though the centers succeed with this in varied degrees.

The search for antibiotic compounds from the natural environment has been going on for seven decades, ever since penicillin entered the market and antibiotic treatments became routine. The evolutionary pressure put on the pathogenic microorganisms induced a rapid spreading of naturally occurring resistance genes, leaving only the option of finding new antibiotics to treat the resistant pathogens. Microorganisms have been extensively mined for their biosynthetic abilities to produce biologically active compounds. To date, more than 23 000 microbial natural products have been discovered. The Actinomycetales are ubiquitous bacteria that have been used for antibiotic discovery for more than half a century, and over 10 000 natural products have been identified from the order.

This paper describes Tempus Custode, a smartphone application with which the user may register working hours and travel time during the work day. The application communicates with a database via a server. The data stored in the database may be manipulated using an administrator tool, mainly for the composition of time reports. In this way, the user?s task of time reporting his day is greatly simplified.The application is able to automatically discriminate between work time and travel time, as it continuously fetches positioning data from the smartphone GPS receiver.

2013. The brave new time.We constantly look forward in time. There is a need today to constantly renew, replace and update almost everything in our lives. Although often stressful, these continual changes and upgrades can open up new possibilities and even be seen as enjoyable and stimulating.Values, opinions, and everything we create, is based on an experience of the past and predictions of what the future might be. I want to take advantage of these thoughts and find out how they relate to our exchangeable culture.

Today more and more municipalities interact across a wide range of sectors. The reasons tostart interacting are varying and for those who succeed with this form of work, there arebenefits in terms of efficiency and knowledge exchanges. But are the reasons that interactalways obvious? Sweden currently has 290 municipalities of varying size and allmunicipalities have basically the same mission, to deliver services to its residents.Information technology allows municipalities to digitize much of the workload, but theintroduction of the technique is not without problems. For small municipalities, there are greatdemands to deliver reliability and support for their internal and external services.

Stump harvest could be found in the late 1970?s and the early 1980?s. And now when the prices on energy are high it has become an interesting topic again. This work has been conducted within Holmen Skog?s stump harvest testing in Norrköping.

This paper describes Tempus Custode, a smartphone application with which the user may register working hours and travel time during the work day. The application communicates with a database via a server. The data stored in the database may be manipulated using an administrator tool, mainly for the composition of time reports. In this way, the user?s task of time reporting his day is greatly simplified.The application is able to automatically discriminate between work time and travel time, as it continuously fetches positioning data from the smartphone GPS receiver.