The process of drug discovery is very slow and expensive. There is a need for reliable in silico methods; however the performance of these methods differs.This work presents a targeted study on how the drug discovery methods used in OpenEye?s tools ROCS, EON and FRED perform on targets with small ligands. It was examined if 12 compounds (markers) somewhat similar to AMP could be detected by ROCS in a random data set comprised of 1000 compounds. It was also examined if EON could find any electrostatic similarities between the queries and the markers.

No other object is in our constant possession such as the mobile phone. The smartphone has been transformed into a worldwide forum for information-rich exchanges between individuals and companies, by which this rapid access to the smartphone has created and continues to create opportunities in terms of communication. Many researchers of today undertake the challenge of studying the smartphone's role as a marketing channel, and the role of the channel is now undoubtedly central in marketing. However, as the importance of marketing communication increases and despite the fact that survey methods are exceedingly dependent on a channel to fulfill its purpose, namely carry out questionnaires, there has been surprisingly little attention to the study of the channel's role and importance when carrying out surveys. The main purpose of this paper is to investigate whether the choice of a communication channel affects the survey outcome and, if so, further investigate how survey methods differ in terms of consumers' attitude and also their perception of their privacy.

South Korea is one of the fastest growing economies of the world and experts claim that it?s headed towards the same direction as Japan. This doesn?t imply that the countries are similar to an extent where companies don?t have to consider the differences while entering the host market. This study was conducted for the purpose of giving a view of the business climate in the countries and thereby could help companies who see the countries as potential host markets.

The Angolan black and white colobus monkey (Colobus angolensis palliatus) is an arboreal primate that inhabits coastal forest fragments on the south cost of Kenya and is consequently vulnerable to forest fragmentations. The study was carried out in March and April 2011 in Diani Beach in Kenya where two of the largest populations of the species are distributed. This study is a pilot study to test methods for a Master?s thesis. The aim was to investigate any variations in use of two habitats of C.a.

This study investigates three different methods for evaluating MOE,Modulus of Elasticity, in field measurements. The purpose is toinvestigate the possibility to use dynamic measurement methods infield measurements that hitherto (2010) has been performed with staticmethods. The objects of investigation are 20 glulam beams. The firstfield measurement took place in november 2007 and applied a staticmethod based on the standard SS-EN 408. The second measurement,described in this study, took place during summer 2010, and appliedstatic as well as dynamic methods.The MOE of wood is affected by a range different factors.

The purpose of this study is to compare the economic differences between withdraw of forest fuel and withdraw of pulpwood in first thinning, to see which method gives the maximum profitability (income - cost). Another purpose is to investigate the economic impact of the thicket cleaning. The study compares four different methods: i) pulpwood output with thicket cleaning, ii) pulpwood output without thicket cleaning, iii) forest fuel output with thicket cleaning and iv) forest fuel output without thicket cleaning. The study was conducted in a 30-years old stand, dominated by spruce, outside Harg in Uppland. The method that generated the best economic net income was pulpwood without thicket cleaning. It generated a positive net of 1,383 SEK per hectare. Forest fuel output without thicket cleaning also generated a positive net in 720 kronor per hectare.

This qualitative study is about the differences and similarities between the organization Friends and schools? methods to prevent bullying. Aggression, bullying and discomfort in schools result in that many students do not dare to go to school because of their fear that they might get attacked and become systematically bullied. Bullying is a universal and persistent problem. In this study the reader will receive a better understanding and get an insight into the problems that teachers and students experience and struggle with every day in dealing with bullying in schools.

The aim of this study is to combine queer theories with quantitative methods. In social sciences, queer theories are being widely and increasingly used. Quantitative method is also widely used, and as a traditional method it can be regarded as a cornerstone in social sciences, sociology in particular. However, the two perspectives, queer theories and quantitative method, seem at a first glance to be very different in their understanding of social phenomena. Queer theories have, with some exceptions, mainly focused on qualitative research concerning such phenomena as sexuality, while the field of science is quite diverse.

The purpose of my study is to investigate teacher?s perceptions of their mission in the preschool class, and how they work to promote children?s written language development. What methods and working methods they use to awaken curiosity and motivate children to read and write. I am using the qualitative research method to get answers to my questions. I have made four qualitative interviews with four teachers in preschool classes from different schools.My questions are:What conceptions does teachers have about their mission in a preschool class?What different methods and approaches does teachers use to stimulate and wake children?s curiosity for reading and writing development?The theoretical basis for my study is the socio-cultural perspective, where learning occurs in interaction.

The aim of my study is to investigate methods which class teachers implement concerning aesthetic subjects in elementary classes. It is a qualitative study about five teacher´s working in different elementary schools. This study investigates how and why teacher´s approaches when they integrate aesthetics in other subjects. It also investigates teacher´s attitude towards aesthetics. My study emphasizes on why they use asthetics and what the importance of aesthetics for children is.

Abstrakt I den här uppsatsen undersöks hur ett narrativ kan drivas inom digitala spel enbart med hjälp av spelmiljön. Syftet är att få förståelse för vad miljöberättande behärskar som en självständig form av berättande och vad författarna kan göra för att uppnå detta mål. För att undersöka problemområdet genomfördes en spelproduktion där metoder framtagna under undersökningens gång applicerades. Produktionen testades av utomstående studenter i medieteknik och resultaten sammanställdes med reflektioner kring vad som uppnåtts och de metoder som applicerats. Undersökningen beskriver arbetsprocessen och metoder och visar hur dessa kan driva ett narrativ med en spelmiljö. Abstract In this thesis examines how to drive a narrative in digital games using only the game environment.

ABSTRACTBackground Calprotectin is a protein found in the cytoplasm of neutrophile granulocytes. In the course of inflammatory bowel disease (IBD), calprotectin is released during chronic inflammation in the gut. Activation of neutrophils during the inflammation is followed by activation and secretion of pro-inflammatory molecules such as calprotectin. Calprotectin is stable in stool up to 7 days and can therefore be used as a non-invasive marker for diagnosis, treatment and measurement of the disease activity in patients with IBD. The most common method for analysis of calprotectin concentration is ELISA.

This is a diploma thesis executed as a part of the examination of the educationalprogram Building engineer ? Construction management at Halmstad University. The aim of the thesis is to compare and evaluate conventional open-cut pipe-laying withhorizontal directional drilling. The thesis includes a comparison of the economic,environmental and time-based aspects of both methods and discusses which factorsthat determine the optimal choice of method.The study is mainly based on previous studies regarding the subject and oninterviews with professionals from the industry.A fictional project with five realistic cases of pipe-laying scenarios was compiled,sent to different companies for calculation, evaluated and compared. Our conclusionregarding when it?s suitable to use which method is entirely dependent on thespecific project.

Assignments and organizations working with exposed women are more and more common in the Swedish society. Both authorities and nonprofit organizations are working actively to strengthen women?s position in the labor market through incentives and other measures. The study shows that the work with exposed women takes place in cooperation between the parties involved. The purpose of this qualitative study was to look into how the professionals were working with exposed women, in different types of organizations.

This is a study on individual development plans (IDPs) in pre-school and their relationship with the teaching performed. Skolverket does not mention the IDPs in their steering documents for pre-school, and have in a separate memo discouraged from the use. Yet reports show that many of the pre-schools in Sweden are using IDPs. Teaching in pre-school is expected to be a mixture of care and learning without clear boundaries to the scientific topics pre-school aims to introduce children to. The purpose of this study is to investigate if the use of IDPs affect the teaching in pre-school.