Genotyping can be used to link genetic variation among individuals to certain diseases or conditions. Some known disorders and states that are dependent on single nucleotide polymorphism (SNPs) are lactose intolerance, venous thrombosis, hereditary hemochromatosis and the difference in sensibility among people to metabolise drugs.In this project a new kit, TaqManÒ Sample-to-SNP KitÔ for extraction of DNA and preparation of the extract for genotyping with real-time PCR and allelic discrimination, was evaluated. QIAamp® DNA Blood Biorobot® MDx Kit was used as the reference method.The purpose of the comparison was to find a method that makes DNA extraction from blood samples cheaper and faster, but with the same reliability as the reference procedure.The results of the evaluation showed a complete agreement of the genotype results between the methods tested, which means that the new method was as reliable as the reference method. The costs of reagents and material would be reduced with 52% if the new method is adopted, that alone would result in a cost reduction of 144 000SEK a year with a sample volume of 650 samples/month. The time for DNA extraction would also be reduced with the new procedure. .

Syfte: Syftet med vår uppsats är att belysa den etiska dimensionen av harm reductionanknuten missbrukarvård. Till vår hjälp har vi haft etiska teorier och sociologen Zygmunt Baumans begrepp. Frågeställningar: Vi har använt oss av två huvudfrågor som vi därunder bryter ner i konkreta frågor. 1 Hur ser de etiska resonemangen ut hos personal verksam inom harm reductionanknuten missbrukarvård?Vilken typ av etik använder de sig av? Har de centrala etiska principer, vilka? Hur ser de på etik och moral? Följer de etiskt formulerade regler? Hur ser de på prohibition? Hur ser de på drogbruk? Hur ser de på människan? Vad driver dem i deras arbete? Hur ser de på harm reductions påverkan på samhället?2 Hur kan man förstå harm reductionmetoders framväxt ur Baumans sociologiska perspektiv?Hur kan harm reductionmetoder kopplas till det senmoderna samhället? Hur kan harm reduction rättfärdigas etiskt utifrån ett sociologiskt perspektiv? Hur kan harm reductions förklarar sociologiskt? Vilka förutsättningar fanns för att harm reduction skulle kunna utvecklas? Hur kan Baumans begrepp förklara harm reductions ställning i det senmoderna samhället? Metod: Vi har använt oss av en kvalitativ metod med intervjuer som redskap.

Emhart Glass AB är en världsledande internationell tillverkare av automatiska glasformningsmaskiner för framställning av olika glasprodukter bl.a glasflaskor och glasburkar. Emhart Glass AB har i dagsläget 14 kontor i 10 olika länder och är sedan 1998 ägt av Bucher Industries. Den svenska divisionen är uppdelade i två enheter. I Örebro tillverkas maskindelar, reservdelar och strategiska komponenter. Komponenterna skickas sedan vidare till Sundsvall för del- och slutmontage.På Emhart Glass Sweden i Örebro har det uppmärksammats att långa ställtider förekommer vid vissa maskingrupper.

This report analyzes and examines a hypothesis for finding a method to optimize thelength of the delubrication process time based on a total charge weight. The work hasfocused on the holding time for delubrication and the total charge weight.An important step in the manufacturing chain of cutting tools is when the greenbodies undergo the sintering process. Today, the delubrication step has the sameprocess time independent of the total charge weight. An implementation of a methodto adjust the delubrication process time would give more consistent quality of thecutting tool´s internal characteristics but also reduce the time course of the sinteringprocess. In the present project two methods for this goal were tested, thedevelopment of an algorithm and a weight interval subdivision with associateddelubrication process times.During delubrication a pressure increase is observed due to the decomposition of thePEG in the powder mixture.

VBG Produkter AB is a process-orientated company that develops, manufactures and markets trailer couplings with belonging coupling equipment, protection equipment against skidding and stands for wagon-bridge for heavy vehicles. The company feels that their set-up time in production for couplings is not at an acceptable level. Due to high demands of customer oriented production the intermediate stock level of included products within the assembly of couplings has gradually increased which has resulted in high inventory holding costs. VBG Produkter applies Kanban in their production, therefore it is important to produce exactly the necessary amount and avoid overproduction. The objective of this project is to suggest appropriate solutions so that VBG Produkter is able to reduce their set-up time in assembly of couplings, by identifying internal and external set-up time for the chosen process bushing cell.

The general consensus is that the gap between the Swedish variable mortgage rate and the repo rate has increased over the last years. Although the Riksbank in recent times has cut its base rate, many banks have chosen either to leave the interest rate on variable mortgages unchanged, or they did reduce it but by less points than the reduction in the repo rate. The linear relationship between the repo rate and the variable mortgage rate has changed over the last decade and the mortgage margins these days are relatively high. This can somewhat be explained by the new rules introduced in the bank sector requiring banks to increase liquidity and equity. Since mortgage loans play an important role in banks? lending business it is of interest to gain knowledge in whether a repo rate reduction latterly has generated a limited affect on the banks lending rates..

To make wave power more competitive on the market Uppsala University leads projects that examine how to accomplish better efficiency in the production. One of these projects is described in this report and examines whether it is possible to make the production of dovetails more efficient by using an industry robot of type ABB IRB6000 S3 M91. This project is using an already presented working method, from a previous project, which involves that the robot picks up the dovetail and moves against fixed cutting machines where the dovetail will be drilled, threaded and milled. Drilling and threading are the sub operations that will be examined in this project where experiments are made with the presented working method and with equipment from Uppsala University.Experiments show whether it is possible to drill the holes in the dovetail within specifications by using the specific robot and the presented working method. The threading operation is examined theoretically if it is possible to accomplish by using the same working method.

AbstractPurpose ? The purpose of this study is to investigate possible reasons for long lead-time in a customer driven production, and how the lead-time can be reduced. To fulfil the purpose the study has been broken down into two questions.1. Whichfactorsaffectthelead-timeinacustomer-drivenproduction?2.

One of the most important components of a harvester is the crane. Most harvester cranes are only possible to pivot (or horizontally rotate) at the crane pillar. Cranab in Vindeln, Sweden, has developed a new type of harvester crane which has an extra pivot point on the outer boom. This makes it possible to reach around residual trees, easing thinning work in dense stands. The aim of the study was to analyze if the use of a pivoting outer boom (POB) crane gave an increase in thinning production and if there were any differences in time consumption between the work elements for the POB crane and a conventional crane. A Valmet 911.3 equipped with a POB crane was used in the study.

This paper deals with the opportunities for the technique of condensation, for wood fired household heaters, on the Swedish market. In this project the condenser is preceded by a scrubber and both energy exchange and separation of unburnt particles have been studied. The facility studied is connected to a wood stove at 30 kW. The tests would show that the effect from the stove never reached above 16 kW. This might be a result of the low temperature of the water going into the stove, from the condenser. In addition to this the wood was not of highest quality and the stove could have needed some maintenance before the tests.

This bachelor thesis is intended to gather the knowledge and experimental data on the winter wheat crop production relevant for Swedish conditions, with focus on sowing time, row spacing and seed rate. This essay is a literature study with a minor component based on interviews with farmers producing winter wheat. The work is divided into a background part where basic knowledge of winter wheat physiology, development and environment interactions are described and one part where results of field trials studies are presented. Optimal date of sowing winter wheat depends on annual weather variations. Because it is difficult to forecast the weather the choice of sowing date should be based on weather statistics, production experience and previous results depending on sowing date.

AbstractA systematic replication study was conducted at the training site at the University of Karlstad. Student therapists performed cognitive-behavioural therapy (CBT) as a part of their master?s degree in psychology.  The systematic replication that took place was based on the work of Hiltunen et al. (2013), who evaluated the efficacy of CBT treatment conducted at the training site previously mentioned.

This diploma work has been carried out in collaboration with the building contractor Sh Bygg Fastighetsutveckling AB in Uppsala with the intention to investigate how the height of a building affects various energy aspects such as transmission losses, infiltration, and the specific energy usage. Three different reference objects have been studied. The reference objects have been simulated for four different heights in the calculation program VIP-Energy.The results show that an increase in floor number can lead to both advantages and disadvantages. As the number of floors increases, transmission losses per square meter floor area decreases. However, as the height of the building increases, the reduction rate decreases.

AbstractPurpose ? The purpose of this study is to investigate possible reasons for long lead-time in a customer driven production, and how the lead-time can be reduced. To fulfil the purpose the study has been broken down into two questions.1. Whichfactorsaffectthelead-timeinacustomer-drivenproduction?2.

Denna uppsats behandlar ett antal stigmatiserade individers möjligheter att återinträda i samhällsgemenskapen efter ett liv i missbruk eller på institution. Detta har skildrats genom individernas livsresa, från inspärrning/inskrivning på totala institutioner till det vakuum som uppstår när de blivit frisläppta eller utskrivna, och vad de därefter har för möjligheter att förändra sin identitet och bli en del av samhällsgemenskapen. Vi har inriktat oss på en verksamhet, som fångar upp personer i ett mellanläge, efter inspärrning men före samhällsintegrering. Verksamheten har till skillnad från statliga behandlingsverksamheter en acceptans för Harm Reduction. I tidigare forskning har vi beskrivit missbruksvården och den svenska narkotikapolitiken.