Background: Chemotherapy and radiation resistance are major causes of failure in cancer treatment. The response to treatment in cancer cells depends on several mechanisms and pathways such as Janus kinases-signal transducers and activators of transcription JAK/STAT pathway. STAT1 was the first described transcription factor in the STAT family. STAT1 is activated by stimulation of signaling proteins such as type II interferon (IFN- ?) and the activated STAT1 translocates from cytoplasm to nucleus.

AbstractThe aim of this essay is to explore how teachers and leisure educators can strengthen and increase students? self-confidence in different ways in their line of work. I chose this inquest for personal reasons and also because it will be of great aid for me since this is what I intend my future profession to be. For this inquest I have chosen to do five qualitative interviews and two unstructured observations. The inquest was also based on relevant literature connected to its purpose.The results show that self-confidence is linked to something the individuals accomplish and that self-esteem is the way they see themselves, an inner feeling.

Bakgrund: I den fysiska vårdmiljön framkom olika förutsättningar för att skapa god omvårdnad då grundläggande mänskliga värderingarna var av betydelse för hur begreppen hälsa och omvårdnad tolkades. De traditionella vårdmiljöerna kunde uppfattas som anonyma och sterila platser av både sjukvårdspersonal och patienter, dessa egenskaper representerar hur fysiskt påtaglig sjukvårdsmiljön var. Syfte: Syftet med denna litteraturöversikt var att beskriva hur patienter inom somatisk vård upplever den fysiska vårdmiljön på sjukhus. Metod: En litteraturöversikt baserad på tio vetenskapliga artiklar med både kvalitativ och kvantitativ ansats. Resultat: Tre huvudteman framkom vid analysen av artiklarna; sjukhusmiljö, vårdavdelningsmiljö och vårdsalsmiljö.

The aim of this Master's thesis is to examine what effect two different models of acquisition have on user satisfaction with information resources at academic libraries. The two models examined are the traditional model where a subject specialist librarian makes the selection, and the user-governed model where the larger part of the selection is based on user requests. The scope is the libraries of Roskilde University, which employs the traditional acquisition model and Malmö University, which employs the user-governed. Both libraries have a user-oriented approach to acquisition. The study encompasses a close examination of the acquisition policy through document analysis and interviews with the librarians in charge of acquisitions at each university, as well as a user-satisfaction survey among the professors and senior teachers on two faculties at each university respectively.

The aim of this thesis is to investigate how librarians view marketing of the library using social media and how this can be used in a marketing strategy. The theoretical framework for this thesis is based on the 7 Ps of the marketing mix, SWOT-analysis and SWOT/TOWS Matrix. The theory is based on planned elements that make up a product or service offered the market. We have used our own interpretation of the theories to analyse our material. Our main method has been a web-based questionnaire, the questionnaire was sent to 523 librarians active at ten large public libraries and its related branches.

Lake lowering in sulphide-rich areas is currently a major environmental impact for surface water. This study focuses on whether there is a relationship between a gradient of lake lowering and surface water impacts in areas of sulphide-rich sediments, in order to better understand their contribution of heavy metals and sulfuric acid. Also, is it a reasonable method to use the reduced lake area in order to quantify the gradient? The survey was conducted by collecting water samples from reference lakes and lowered lakes from south to north in coastal areas within the county of Västerbotten. Water samples were then analyzed for TOC, pH, conductivity, anions, base cations, alkalinity, acidity, sulfate, Al, Cd, Fe, Mn, Cu, Zn and Pb.

Det primära syftet med uppsatsen är att studera relationerna mellan de nya och de etablerade börsmarknaderna i EU för att se om det ha skett någon förändring under perioden 1996-2005. Ett sekundärt syfte är att undersöka huruvida den finansiella integrationen inom unionen har blivit starkare under den studerade tidsperioden. I syfte att kunna besvara de frågor som vi är intresserade av använder vi oss av VAR-metoden. Med hjälp av "impulse response" beräknade vi hur snabbt en händelse sprider sig mellan de undersökta börsmarknaderna samt hur lång tid det tar innan dessa åter är i jämvikt. "Variance decomposition" talar om för oss i vilken utsträckning de olika börsmarknaderna påverkar varandra.

Idamari Törnberg & Marcus Tillberg (2011).Nu gäller det! Varför slutar då ungdomar spela ishockey? ? En kvantitativ enkätstudie om fortsatt eller avslutande ishockeykarriär efter uttagningarna till distriktsförbundslag i Västerbottens län. (Now is the time! Why do teenagers stop playing ice hockey? ? A quantitative survey study about continued or ending ice hockey career after tryout to Team Västerbotten) Bachelor Essay in Swedish. Umeå: Umeå University, Department of education.AbstractThis Bachelors thesis is a survey study on why talented teenagers in the county of Västerbotten, Sweden dropout of, or proceed the sport ice hockey.

Assignments and organizations working with exposed women are more and more common in the Swedish society. Both authorities and nonprofit organizations are working actively to strengthen women?s position in the labor market through incentives and other measures. The study shows that the work with exposed women takes place in cooperation between the parties involved. The purpose of this qualitative study was to look into how the professionals were working with exposed women, in different types of organizations.

I denna uppsats har jag valt att studera självstärkande inslag i förskoleverksamhetens vardag och knyta an dessa till teoretiker som Erikson, Maslow samt Sommer. Undersökningen är baserad på tidigare forskning, ovan nämnda teoretiker samt en enkätundersökning. Enkätundersökningen genomfördes på en förskola med 16 pedagoger och kan därför ses som en grund för ett vidare forskningsarbete. Studien visade att det vanligaste sättet att stärka barnens självkänsla var att låta dem försöka själva innan de fick hjälp av någon vuxen, uppmuntra dem att försöka på nytt samt att ge positiv respons när de lyckades. Jag fann av svaren flest anknytningar till Maslow samt Sommer, endast några inslag kunde knytas till Erikson.In this examination I?ve chosen to look at educationalists work procedures around children?s self-esteem and how to connect those procedures with theorists as Erikson, Maslow and Sommer.

Several diseases increase the risk of thrombosis in dogs and cats, often with a fatal outcome. Currently there are no definite treatment guidelines for the use of thrombolytic and thromboprofylactic agents in veterinary medicine. None of these drugs are approved for dogs and cats in Sweden. Medicines aimed for humans have been used tentatively. This literature study is an investigation of what is currently known about the effects and safety of these pharmacological agents when used for dogs and cats.

The main interest of this study was to investigate whether there is hyperglycemia or hypoglycemia in cows suffering from abomasal displacement and to evaluate the effect of transport on blood glucose. Thirty-six cows with left- or right-sided abomasal displacement were included in the study together with 17 cows with other diseases for comparison. Fifteen cows with abomasal displacement and 7 cows with other diseases were sampled before transport. One third of the cows with abomasal displacement had hyperglycemia when the transport effects were corrected for. Separating this group in left- and right-sided abomasal displacement we found significantly higher blood glucose and insulin levels among cows with right-sided abomasal displacement. An explanation for this difference may be a strong stress response secondary to the right-sided dislocation.

Syftet med studien är att få en ökad förståelse för vilka faktorer som påverkar konsumentens butiksupplevelse. Detta för att få kunskap om hur butiker kan möta kundens behov, genom utformning av butiksutrymmet samt personalens bemötande. Studien ämnar ta reda på vilka faktorer som skapar en positiv respektive negativ respons från konsumenten. Undersökningen genomfördes genom deltagande observationer, där en person åt gången observerades och intervjuades under en shoppingtur. Detta för att ta del av både konsumentens åsikter samt agerande i miljön.Ett ord som var återkommande i samtliga deltagande observationer var struktur, då deltagarna ansåg att butikens struktur var mycket viktig för helhetsintrycket.

Webbapplikationers komplexitet och mängden avancerade tjänster ökar. Loggning av aktiviteter kan öka förståelsen över användares beteenden och behov, men används i för stor mängd utan relevant information. Mer avancerade system medför ökade krav för prestandan och loggning blir än mer krävande för systemen. Det finns behov av smartare system, utveckling inom tekniker för prestandaförbättringar och tekniker för datainsamling. Arbetet kommer undersöka hur svarstider påverkas vid loggning av serverdata, enligt datainsamlingsfasen i web usage mining, beroende på lagringsstrategier.

The objective of this bachelor thesis is to examine how some larger Swedish public libraries reason about the use of social media as part of their activities and outreach. To attain the purpose three research-questions were established; why does the public library use social media? How does the public library utilize social media? What extra value do librarians believe that use of social media can add to the libraries? function? The methodology used in the thesis is qualitative interviews. Six interviews were conducted with librarians in charge of social media at their respective libraries. Five of the interviews were conducted by telephone and one by email.