The horse is a homeothermic animal and to keep a constant body temperature in winter season is important. Acclimatisation is to provide means for a good thermal insulation consisting of skin, hair, and an outer air layer. The skin covers the horses body and it is composed of three main layers where the top layer of the epidermis consists of dead keratinized cells that are constantly being sheed. The dermis is composed of collagen connective tissue that give the skin its strength. The bottom layer with subcutaneous fat provides a thermal insulation and can be used as an energy reserve in cold weather.

Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.

The giant otter (Pteronura brasiliensis) is listed as an endangered species and scientific litterature concerning its biology and behaviour is scarce. The current study observed a group of three giant otters in a Swedish zoo. First the otters normal behaviour was recorded. Then the aim of the study was to see if the otters behaviour changed when given blue mussels (Mytilus edulis). Furthermore the aim was to see if the otters displayed any tool-using behaviour when given mussels.

Introduction: Breast pain, mastalgia, is a common problem for many women. The pain can cause so much concern that the woman seeks help in health care. The cause of concern is often that that the pain may be due to breast cancer. Women with mastalgia are referred for mammography to investigate the cause of the pain. Experience says that the mammography is mostly normal.Aim: The aim of the study was to get an overall picture of the results of the mammograms performed on Mammography SU / Sahlgrenska in 2011.

Ultrasound is a diagnostic aid often overlooked by the veterinary practicioner who works with farm-animals. However, it?s use increases, particulary for breeders where ultrasound has long been used to evaluate ovaries and to diagnose pregnancy or disturbances in reproduction. There is much knowledge in how to examine ovaries and uterus by transrectal ultrasound, but when it comes to doing ultrasound of other organs in the abdomen the knowledge is more limited. Cows are very large animals, so it is not possible to examine everything inside the abdomen with ultrasound, simply because the ultrasound beam has a limited penetration. There is also lots of gas inside the gastro-intestinal tract of a cow, mainly in the large intestine and the rumen, and that makes it impossible to examine the organs behind the gas since the ultrasound waves are reflected when reaching the soft tissue-gas interface.

The research in the field of biotechnology is rapidly developing all over the world. Modern biotechnology offers unique opportunities, simultaneously as it gives rise to a number of ethical issues. Preimplantation genetic diagnosis (PGD), PGD/HLA (Human Leucocyte Antigen) and germline gene therapy (GLGT) are controversial techniques. PGD gives a possibility to identify a genetic disease prior to the embryo?s implantation in the uterus.

SummaryPatients with burn injuries involving more than 20 percent of the total body surface area lose a lot of fluid and are in the risk of developing a severe hypovolemia. Fluid resuscitation is a corner stone in burn care and is important for preventingfurthercomplications. The most common resuscitation formula is the Parkland Formula. Hourly urine output is a measure used to evaluate if the fluid given is sufficient enough to maintain a sustainable tissue perfusion. Inhalation injury, abuse of alcohol and drugs are some of the factors that may increase the amountoffluid needed.

SummaryPatients with burn injuries involving more than 20 percent of the total body surface area lose a lot of fluid and are in the risk of developing a severe hypovolemia. Fluid resuscitation is a corner stone in burn care and is important for preventingfurthercomplications. The most common resuscitation formula is the Parkland Formula. Hourly urine output is a measure used to evaluate if the fluid given is sufficient enough to maintain a sustainable tissue perfusion. Inhalation injury, abuse of alcohol and drugs are some of the factors that may increase the amountoffluid needed.

I samband med att en organdonation ska genomföras görs en uttagsoperation, där organen tas från donatorn. Inför detta ingrepp vårdas patienten på intensivvårdsavdelningen och det finns god tillgång på forskningom hur personalen där upplever vårdandet av en tilltänkt donator. Däremot brister forskningen om hur den perioperativa personalen upplever sitt medverkande vid uttagsoperationen. Syftet med studien var att beskriva perioperativa sjuksköterskors upplevelser av att medverka vid en uttagsoperation från en avliden inför organdonation. Studien genomfördes som en kvalitativ deskriptiv studie och kvalitativ innehållsanalys.

SummaryPatients with burn injuries involving more than 20 percent of the total body surface area lose a lot of fluid and are in the risk of developing a severe hypovolemia. Fluid resuscitation is a corner stone in burn care and is important for preventingfurthercomplications. The most common resuscitation formula is the Parkland Formula. Hourly urine output is a measure used to evaluate if the fluid given is sufficient enough to maintain a sustainable tissue perfusion. Inhalation injury, abuse of alcohol and drugs are some of the factors that may increase the amountoffluid needed.

The main interest of this study was to investigate whether there is hyperglycemia or hypoglycemia in cows suffering from abomasal displacement and to evaluate the effect of transport on blood glucose. Thirty-six cows with left- or right-sided abomasal displacement were included in the study together with 17 cows with other diseases for comparison. Fifteen cows with abomasal displacement and 7 cows with other diseases were sampled before transport. One third of the cows with abomasal displacement had hyperglycemia when the transport effects were corrected for. Separating this group in left- and right-sided abomasal displacement we found significantly higher blood glucose and insulin levels among cows with right-sided abomasal displacement. An explanation for this difference may be a strong stress response secondary to the right-sided dislocation.

ABSTRACTBackground: Endometriosis is a chronic disease where the tissue, that the uterus contains,also can be found outside the uterus.The objective of the study was to investigate young women?s experience of endometriosisand how they experience the care.Method: Fourteen young adults were asked to participate and eight of them did participate.They were all in the range of age 14-20 and they all had had contact with a unit forendometriosis in Sweden. Semai-structured interview was chosen as the data collectionmethod. An interview guide was used during the interviews. For the analysis aphenomenological method with focus upon experiences was used.Results: The result showed that the young adults? experiences in the daily living containedpain, alienation, tiredness and side effects.

Cysteinproteaset cathepsin B har en trolig roll i vävnadsnedbrytningen vid kronisk parodontit då det visats kunna bryta ner extracellulära komponenter. Cystatin C är en fysiologisk inhibitor av cathepsin B och båda har kopplats till parodontal sjukdom. Syftet med studien var att undersöka närvaro av samt lokalisera cathepsin B och cystatin C i gingivala biopsier från patienter med kronisk parodontit. Närvaro och lokalisation av cathepsin Bs och cystatin Cs demonstrerades genom immunohistokemisk metod av kryostatsnittad vävnad. Polyklonal kanin anti-human primär antikropp för både enzym och inhibitor användes.

This Master Thesis has been carried out in cooperation with Ursus Medical AB (URSUS) which markets, assembles and sells the Rotex Screw Needle Biopsy Instrument ®. The instrument is delivered with an instrument holder. Customers had expressed dissatisfaction over that they needed to use two hands during a biopsy procedure, which resulted in a project to develop a new instrument holder.The project aim was to create concepts for how the new instrument holder should be designed, with focus on the mechanics. The new instrument holder would build on the existing basic principle that the screw needle and the cannula were screwed into the tissue. The thesis work would result in a technical solution and a functional prototype of the chosen concept.To achieve this, a generic product development processes were used and began with a comprehensive literature review.

Background: Prediabetes is caused by relative insulin deficiency and insulin resistance in the body tissue which leads to abnormal blood glucose levels. Prediabetes can over time lead to type 2 diabetes mellitus. To prevent the onset of type 2 diabetes and its complications, it is important to identify early elevated blood glucose levels and thereby prediabetes.Objective: To describe nurses' knowledge and experience regarding the management of patients with prediabetes.Methods: Qualitative descriptive design with individual interviews. Three nurses, three community health nurses and three diabetes nurses were interviewed.Results: The result can be understood from the nurses' experiences of encountering patients with prediabetes. An overarching theme in the analysis was that the nurses are working or aspiring to work preventively.