Kolorektal cancer (CRC) är en av de vanligaste cancersjukdomarna i världen med cirka 1 miljon nya detekterade fall per år. Special AT-rich sequence-binding protein1 (SATB1) är ett celltyp-specifikt kärnmatrix-associerat DNA-bindande protein, vilket utgörs av AT-rika DNA sekvenser. Det har tidigare demonstrerats att en annan medlem i SATB-familjen, SATB2, uttrycks på ett vävnadsspecifikt sätt i normal mukosa i nedre mag-tarmkanalen och i CRC. ?-catenin är en intracellulär mediator i Wnt/?-catenin signaleringsvägen, som spelar en viktig roll i kolorektal carcinogenes.

As the volumes are entering the world of computer graphics the pure volume visualisation becomes a more important tool in for example research and medical applications. But the advance in haptics --- force feedback from the computer --- is behind. In volume haptics no equal to the proxy method so popular in surface haptics has yet emerged. Some implementations of volume haptics even use surfaces as intermediate representations so that surface haptics can be used.The intention of this work was to create natural feeling haptic feedback from volumetric density data using pure volume haptics. The haptic algorithm would be implemented in Reachin API for the Reachin Desktop Display, together with other parts to build up a usable volume visualisation environment.To achieve the feeling of stiffness and friction dependent on tissue type, a proxy based method was developed.

INTRODUKTION OCH SYFTE: Tidigare studier av kooperation och ortodonti har visat att ett av de bästa sätten att öka patienternas kooperation är genom att övervaka användningstiden och påminna patienten om att använda sin apparatur. Den här pilotstudiens syfte var att undersöka om någon utav två olika typer av påminnelser objektivt ökar användningstiden vid behandling med avtagbar apparatur eller inte. MATERIAL OCH METOD: 18 patienter i åldrarna 9-14 års ålder från en patientpopulation som behandlades vid avdelningen för Ortodonti, Odontologiska Fakulteten på Malmö Högskola, deltog i studien. Patienterna hade olika typer av bettavvikelser som gjorde dem behandlingsbara med antingen van Beek eller expansionsplåt. Patienterna placerades slumpmässigt in i en av tre grupper, alarm, kalender eller kontrollgrupp. Användningstid registrerades objektivt med en TheraMon®-timermodul som placerades inuti den ortodontiska apparaturens akrylbas. RESULTAT: Alarm-gruppen hade högst genomsnittlig användningstid.

Obese horses with insulin resistance are often also afflicted with laminitis. Horses with these symptoms are given the diagnosis equine metabolic syndrome (EMS). Signs of insulin resistance are excessive accumulation of adipose tissue on the neck, around the withers and on the dorsal area of the hindquarters. Insulin resistance means that the function of insulin is defective and does not stimulate glucose uptake by the cells in the body in the correct way. This will result in an increased insulin release.

The use of transrectal ultrasonography of the uterus is a fairly new method for early pregnancy diagnosis. In the present study 40 cows and 10 heifers were examined 16, 19, 22 and 25 days after artificial insemination to decide on what day an accurate pregnancy diagnosis could be made under field conditions. A 5 and 7,5 MHz transducer were used in all examinations in order to determine wheter one of them was better for the present purpose. The animals were also examined for clinical signs of oestrus. The results shows that an accurate pregnancy diagnosis "not pregnant" was easier to make on day 22 than on day 25 since most of the not pregnant cows then were in heat.

Laminitis is a debilitating disease causing much suffering to horses and ponies all over the world. It is manifested in the hooves as a mechanical failure of the suspensory apparatus between the hoof capsule and the distal phalanx. Due to the weight of the horse the disease may result in a dislocation of third phalanx. Six healthy standardbred trotters were used in this study on whether standardbreds tolerate forced recumbency as well as Shetland ponies. Recumbency was induced pharmacologically but maintained only by lowering the ceiling height of the box to a height of approximately 125 ? 140 % of the horse´s thoracic height.

The purpose of this literature review was to describe the paths of exposure and accumulation of organic pollutants into the tissues of farm animals. Organic pollutants can be spread in the environment by air and rainwater. Farm animals can be exposed to these pollutants for example by eating soil or contaminated plants. Many of the pollutants can then accumulate in the fat tissues of the body because of their lipophilic character. Brominated flame retardants and perfluorolated compounds are both pollutants of current interest.

Mussel meal is a potential source of protein, with a good composition of amino acids, for laying hens and broiler chickens, and may replace the use of fish meal in organic poultry production. Lead and cadmium are heavy metals which occur in the environment and can be accumulated in mussels. When poultry are exposed to heavy metals, the metals are absorbed in the small intestine and distributed in the body in the form of ions, complexes or bound to proteins. In poultry, lead accumulates in bone tissue, liver and kidneys, while cadmium accumulates in liver and kidneys. Generally very low concentrations of these heavy metals occur in muscles of broilers which have been exposed to feed contaminated with cadmium or lead.

Veterinary hospital care and advanced veterinary services are rapidly growing industries. As of January 1, 2010, veterinary nursing became a licensed vocation, the title of veterinary nurse became protected, and the act regulating competence among the professions of the veterinary field was extended. These changes, along with increased demands and expectations from owners, have given rise to greater demands on the staff's qualifications and have increased the need for well-educated staff with expertise in several different areas. The aim of this study was to find out what the licensed veterinary nurse can do in terms of rehabilitation for the hospitalized equine patient suffering from orthopedic injury. This has been carried out through qualitative interviews with veterinary surgeons experienced in treating such patients, and also by reviewing the relevant literature.

In metabolism Mg plays an important role because it affects many cellular enzymes in the body. The energy metabolism and protein synthesis are dependent on Mg as an enzyme activator, Mg is also involved in the synthesis of RNA and DNA. Absorption of Mg primarily takes place over the ruminal epithelium in ruminants. The main storage of Mg is in the bones but that can only be reached if the cow is in great need of calcium or phosphorus, it's a hormonal regulated process that induces catabolism of bones. Free and available sources of Mg are found in soft tissues and in the extra cellular fluids that includes cerebrospinal fluids and blood.

Approximately 20% of the milk within the udder of a cow is stored in the cistern and immediately available for milk removal, while activation of the milk ejection reflex is required for removing the remaining milk stored in the alveolar compartment. The aim of this literature review is to describe, evaluate and consider implications of the three different suckling activities that the calf displays during a suckling bout. In terms of milking, these phases are represented by pre-stimulation, stimulation during milking and post-stimulation. Pre-stimulation is commonly performed in order to induce the milk ejection reflex, whereby the hormone oxytocin is released and the alveoli in the secretory tissue are contracted. Time requirements regarding pre-stimulation must be considered in relation to lactation stage and milking interval.

När en patient drabbas av en total hjärninfarkt och blir aktuell för organdonation ställs det höga krav på intensivvårdssjuksköterskan. Tidigare studier visar att intensivvårdssjuksköterskor oroas av att vårda blivande organdonatorer och samtidigt stödja dennes närstående. Syftet var att belysa intensivvårdssjuksköterskors upplevelse av att stödja närstående till patienter med total hjärninfarkt i samband med organdonation. En kvalitativ metod med innehållsanalys av en fokusgruppsintervju genomfördes.Det framkom två huvudkategorier, Närståendes behov och Intensivvårdssjuksköterskans förmåga att ge stöd. Intensivvårdssjuksköterskans upplevelse påverkades i hög grad av hur närstående reagerade på situationen gällande organdonationsprocessen.

Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.

In Sweden, the most common way to castrate a bitch is by midline approach. In this study, flank and midline approaches are compared in order to evaluate incision by the flank as an alternative technique for ovariohysterectomy in the bitch. The study was performed on straydogs in the central part of Thailand under field conditions. 32 bitches were included in the study. The castration technique was by flank and midline approach, alternating with every other bitch.

So far, only limited research has been carried out on viruses infecting raspberry, even though the diseases that these viruses cause result in economical losses for raspberry growers. Raspberry ringspot virus (RpRSV) belongs to the family Comoviridae and the genus Nepovirus. Nepoviruses are characterized by their icosahedral virus particles and bipartite genome of single-stranded (+) RNA (RNA-1 and RNA-2). These viruses are transmitted mainly by nematodes of the genus Longidorus, which feed on the roots of plants. RpRSV causes disease in raspberry, grapevine, strawberry and many other plants.