Scrapie is an infectious neurologic disease in sheep caused by prions, corresponding to transmissible spongiform encephalopathies (TSEs) in other species. The prion is presumably constituted of PrPSc, the misfolded form of the normal endogenous prion protein, PrPC, which is found in practically all cells in the body. PrPSc can induce a conformational change in PrPC and misfold it as an imprint of itself; this is how prions amplify and spread. The process of conformational change is poorly understood and there might exist intermediate forms between PrPC and PrPSc. Bioassay using mice has traditionally been the golden standard in prion studies but is limited by cost and time.

The purpose with the study is to see how middle managers in communal elderly care looks at the implementation of the salutogenic way of working in their operations. And how it affects the middle managers working situation. We studied which scope of actions middle managers has in the salutogenic way of working. We had previous knowledge that the salutogenic working way is an ongoing work of development in several communes, and therefore we chose to study in a profound way how this work of development affects the middle managers working situation. To reach a deeper knowledge about how the salutogenic way of working affects the middle managers working situation we conducted a qualitative study with been seven semi-structured interviews with middle managers in different geographical communes.

The essay deals with the understanding of the two key concepts from Sein und Zeit (SZ) mentioned in the headline, including a debate on the issue of das Man in Inquiry: an Interdisciplinary Journal of Philosophy. It is noted that reading SZ involves being simultaneously written by the work in a process of reciprocity; this entails a questioning of alleged possession of this or any work, it having been made accessible to the public by its publication.Das Man, as a concept for inauthenticity, needs a counterpart for authenticity, which in SZ is provided by Eigentlichkeit, Self-ownership.This comes into existence via ?being-towards-death?, where the caring being, as a being of possibilities, encounters its ultimate possibility death which is also the end of possibilities.The Inquiry debate, the main contenders of which were Hubert Dreyfus and Frederick Olafson, hinges on the question whether das Man should be understood primarily as ?at bottom a deformation of Mitsein? (Olafson) or ?the conformity necessary for the institution of collectively intelligible social practices (Dreyfus, in the words of his advocate in the debate, Taylor Carman). Both sides, however, give evidence of misreadings of SZ of a kind that call for an explanation. The proposal is that this could be given in an analysis of such a rhetoric of polemics that transforms SZ into a state of Vorhandenheit when making it an object of investigation by the contenders rather than such a tool for being-changed that is mentioned above.The relation between the two aspects of das Man, as oppressive know-all or as forms of established truth for Dasein, remains unsolved, however.

Type 2 diabetes is a growing disease in the population which includes that older people are a risk group. With the disease grows even cost?s. A lifestyle change is a major part of the treatment for type 2 diabetes. There are several factors that suggest positive effects on prevention among the elderly where, among other things, economic and health benefits are presented.

Purpose:The purpose of this study is to improve the knowledge regarding how entrepreneurial companies act and behave in relation to human capital, by studying their decision-making process for human capital investments. Furthermore this study shall enrich the understandings for how their way of handling human capital investments might change over time along with the development, growth and aging of the company.Methodology:For this case study the authors have chosen a qualitative approach. The authors have collected the empirical data by interviewing the CEO?s of six different entrepreneurial companies. To be able to process and analyze the empirical data the authors have used various theoretical frameworks and also previous studies.Theoretical framework:The theoretical framework brings up human capital and its importance, but also its role in the entrepreneurial company.

The costs of logging and of transportation with truck are dominating the total cost of wood delivered at industry. To support the profitability for the members' forestry the processing and handling with the timber has to be as efficient as possible. Increased length of pulpwood in thinning is one conduct that can result in higher productivity and/or lower costs. The study is scaled as a system analysis with the aim to exemplify the differences between working with 3- and 4-meter as standard length of pulpwood, related to biological aspects, timber receipts, cost of logging and cost of transportation with truck. Important aspects are if the change is technically and biologically feasible and economically profitable.

The Swedish government has made the decision to transform the talking book system from an analogue system to a digital system called DAISY by the end of 2004. The purpose of this Masters thesis is to examine how public libraries are affected by this system change. This is carried out by studying the current situation in public libraries concerning the transition to DAISY. This qualitative oriented study is primarily based on interviews with four librarians and three library managers at six public libraries. Management by objectives is here seen as a suitably theoretical framework since public municipal libraries are partly regulated by the governments goals and laws.

Abstract. Risk assessment for future violence is an important part of today's forensic psychiatry, and including dynamic risk factors in risk assessment is important because it has been shown that risk can change over time. However, previous research has suggested that perpetrators of homicide are different than perpetrators of other violent crimes. The aim of this study was to describe and analyze risk assessments of future violence for forensic psychiatric patients convicted for homicide (n = 45) and forensic psychiatric patients convicted for assault (n = 91). To do this, differences within the groups and between the groups were analyzed.

AbstractThis thesis analyzes the Russian Foreign Policy Doctrine from a broad theoretical perspective, with the aim of describing and explaining the doctrine using a number of theoretical approaches. Russia's foreign policy has undergone substantial changes since Vladimir Putin became president in the year 2000, involving a radical shift in foreign policy objectives and thereby moving away from the more confrontational and distrusting policies which characterized the Boris Jeltsin regime. Putins doctrine, based on pragmatism and seeking partnership and collaboration with the West, can be described as a near revolutionary re-orientation of Russia's foreign policy guidelines, meaning a transformation of the country's self image which implies a rejection of great power status and a search for a new role in the international community.Our thesis has examined explanatory variables such as the domestic political situation in Russia, the contemporary international system and President Vladimir Putins system of beliefs in order to describe and explain the doctrine. Our results show that the doctrine is largely a product of Putins personality, values and beliefs, but also to a large extent a consequence of necessities, namely the poor Russian economy and the fact that the country no longer can withstand an all out conflict with the West involving an excessive arms race.Keywords: Vladimir Putin, pragmatism, realism, domestic politics, radical change..

Background: Around the world, markets deregulates, which leads to increased competition. Meetings between the consumer and the employees of a company determine how the customer perceives the company and / or its brand. This has result in that many companies have realized the importance of internal using the same marketing skills that are used externally. In 2009, pharmacy market went from being a monopoly market to be a regulated competitive market.Problem: Is there any internal conditions for a private company, whose culture and structure was formed under a state monopoly, to create a strong corporate brand?Purpose: The purpose of this paper is to, through a case study, analyze and evaluate the internal marketing in a company which has undergone a change of ownership and retained the same staff.Method: Through interviews with key personnel and staff , data was gathered for the case study, which means that the method is qualitative.

The purpose of this study is to see a display on how family, gender and sexuality are produced in four same-sex parents? stories about their children?s pre-school start. The question formulations that have been used were aimed to find out what expectations and concerns parents may have on the pre-school organization, if the parents have any saying regarding the organization, if the pre-school have worked with equality and how they have been treated as a family. The method used is a qualitative study based on interviews. Four lesbian women have been interviewed on their experiences of their children?s pre-school start and after finishing the interviews the content has been analyzed from different viewpoints found in the material.

In the European Union and in Swedish labor law, permanent employment is the main goal for employment of workers. An exception to that rule is temporary employment. The Swedish rules relating to temporary employment have undergone several changes since the Employment Protection Act was implemented in 1974. The last reform in 2007 has received criticism by respondents for not following the Union directive on fixed-term work, which went into effect in 2001. In 2010 the European Commission opened an infringement case against Sweden, after a complaint from a Swedish employees? organization.

 Background: Self-injury can be defined as deliberate harm one's own body without conscious intent to commit suicide. These patients need skilled care. Purpose: Illuminate nursing staff attitudes and treatment of patients with self-injury behaviour for individuals diagnosed with borderline personality disorder. Method: A general literature study has been made. Based on the objective was a literature search in various databases with ten relevant articles were selected and reviewed.

This essay deals with the various difficulties that can arise in conversations and meetings with parents and colleagues in the preschool world. The essay is based on two self-perceived stories that culminate in dilemmas that are difficult to assess, where our own actions come into question.The purpose of this essay is to gain a greater understanding and awareness of why we become insecure when our communication with others fails. Our research questions assist us in gaining an understanding that our own and others' behavior in meetings and conversations can be influenced by past experience, ourvalues and our emotions. This means, for example, that we must be aware that our values - ideal images, functions as both our guide and trip wires. We must also bear in mind that our ability to manage our own emotional reactions is  significant when it comes to facing our own and others' feelings.

There is an old saying, that after Epaminondas nothing was ever the same again. In this thesis I will focus on three questions: "Epaminondas the man." Who was he? "Epaminondas the general." How did he change the technique of warfare that made it possible to beat the Spartans? "Epaminondas, founder of cities and wall-builder." How did he build the walls around the cities he initiated, that made them resist enemy attacks for many years to come?While seeking the answers to yhese questions I will make a contextual analysis to get the historical background to all the phenomina involved..