Denna rapport kommer att redogöra för NK-cellers (Naturliga mördarceller) beteende vid odopat tillstånd. Det vi kallar dopning är när NK-celler aktiveras genom interleukin-2, detta är en signalerande molekyl i vårt immunsystem som reglerar aktiviteten hos vita blodkroppar vilka utgör en del av immunförsvaret.Med hjälp av ett par mikroskopfilmer har vi kunnat följa varje enskild NK-cells migration(rörelse) och interaktion med våra målceller i ett prov under en 8-timmars period. De målceller vi använder är en sorts tumörceller, HEK 293T(Human embryonic kidney 293T cells. Vi har valt att spåra cellerna manuellt med ett program kallat ImageJ och automatiskt med ett matlabprogram, Baxter algorithm. Anledningen till att vi dessutom valt att spåra automatiskt är för att kunna avgöra hur väl detta program kan spåra celler.

This report is a thesis on requests from Sandvik Mining and Construction (SMC) in autumn of 2012. The goal of this work was to study the feasibility of creating and implementing an Equalized preventive maintenance program in SMC maintenance operations and reduce downtime for preventive maintenance (PM). To investigate whether this was possible, the authors studied the current procedures for the PM. The authors have collected and analyzed all relevant information within the maintenance department reporting system as well as through interviews determined whether it is practical to introduce a Equalized PM programs. The authors had also studied the possibilities to entrust part of the maintenance work to the operators of the machine cells.

Lactobacillus reuteri has been used as probiotics in piglet and chicken feedings as well as in different diary products for humans. In this EEF-work I have shown that L. reuteri can be an alternative for treatment of vaginitis in laboratory rats used for breeding. In a breeding stock with 3000 animals some animals had a vaginal infection with ??haemolytic streptococci group G.

Atopisk dermatit hos hund (CAD) är en kliande hudsjukdom med komplex patogenes som involverar felreglering av immunförsvaret, allergisk sensibilisering, defekter i hudbarriären, mikrobiell kolonisation samt olika miljöfaktorer. Dock är den inbördes relationen mellan dessa faktorer inte klargjord. En ökad förståelse för sjukdomens patogenes, bland annat den immunologiska bakgrunden inklusive vilken T-cells- och cytokinprofil som kännetecknar sjukdomen, skulle kunna öka drabbade hundars livskvalitet genom förbättrade behandlingsmetoder. Studier har undersökt cellinfiltrat och visat att både CD4+ och CD8+ T-celler förekommer i ökade mängder i huden hos AD-hundar, och således att det finns Th-celler samt CTLs och/eller suppressoriska T-celler i denna hud. Dessa studier hittade också förhöjda CD4/CD8-kvoter, vilket visar på en ökad lymfocytreaktivitet.

Akademiska hus is a real estate company that specializes in providing Swedish universities with housing facilities for educational and research purposes. The company strives to reduce its use of energy by 40% between the years 2000 and 2025. The aim of this thesis is to determine which measures can be taken to reduce the need of purchased energy in a building that is used by theSwedishUniversityof Agricultural Sciences inUppsala.In order to determine the results of various changes to the building envelope and ventilation system, the building was modelled in the computer simulation program VIP-Energy. Other proposed changes to make the use of energy more efficient concerned water use and lighting. The need of purchased energy can also be reduced by producing electricity or heat on site, using solar energy.Results show that economically viable measures include upgrading windows and faucets, adjusting control systems for ventilation and lighting, and installing roof mounted solar panels for power production.

Fibroblast growth factors are signaling peptides that controls important cellular processes such as proliferation, differentiation, migration, adhesion and survival. Through binding to different types of receptors on the cell surface, these peptides can have different effect on the target cell. Which effect that is achieved depends on many factors. Thus, each of the 24 known FGFs different biological responses. The FGF receptors (FGFR 1-4) initiates different intracellular pathways which in turn leads to different biological responses.

This master thesis was a subtask of a project called EMIR-1. The goal with the thesis was tobuild a system for particulate mass measurements in one of the engine test cells at KTH. Theparticulate mass measurements are planned to be measured with a TEOM.The exhaust gases must first be diluted with air before the sample is sent to the TEOM.Therefore an ejector diluter for this matter also was designed and evaluated in the thesis.Emissions measurements have been done both with and without dilution to determine thedilution ratio. Tests have been done for different speeds and loads.Problems with stability of the dilution ratio have been an issue throughout the process andpressure pulsations in the exhaust pipe are believed to be the cause. More tests have to be done tomake sure that this is the problem.One idea is to make the inner diameter of the diluter nozzle smaller and see if it changes thedilution ratio stability.

The dog has often served as a model animal for humans in scientific studies. This is due to the fact that dogs are susceptible to a wide range of diseases which also affect humans. One example is cancer, a condition that affects dogs as well as owners. Neoplastic diseases account for 18-23 % of all deaths in dogs (Bonnet et al., 2005 and Jagielski et al., 2002). Mammary tumor, or tumor of the breast, is the most common tumor form in intact dogs and women (Im et al., 2013). Mammary tumors originate in the udder, and are classified according to their histological characteristics.

The study aims to investigate the feasibility of small-scale electricity production with solar electricity systems, also known as PV (photovoltaic) systems, in Australia. Due to the global warming, sustainable energy has in recent years become an increasingly important issue, both internationally and in Australia. With one of the largest dependencies on fossil energy sources in the world, the country's abundant solar radiation is a possible solution to this issue.Both the technical and the economic feasibility of small-scale PV systems were investigated. On the technological side, the electricity generation, distribution and consumption systems were studied. On the economical side, the parameters that drive the profitability of a PV investment were investigated.

The vertical electronic excitation energies for the narrow-bandgap polymers LBPF, EP37 and EP62 have been calculated using Density Functional Theory (DFT). Also the vertical excitation energies for the acceptor unit of LBPF have been calculated using the Hartree-Fock (HF), DFT and Coupled Cluster (CC) methods. The calculations cover the visible and infrared wave length region and two strong transitions are obtained, one corresponding to the pi to pi* transition and one corresponding to the pi to Acceptor transition. The excitation energies obtained from DFT are below the corresponding experimental results and attempts have therefore been made to perform bench-marking calculations using a hierarchy of CC methods..

This thesis is made by Carl Persson and Alejandro Saavedra for Gryaab. Gryaab is Gothenburg?s water processing plant and produces about 60 GWh biogas annually with a flow around 1150 Nm3/h. Gryaab wants to research their possibilities to become independent with electrical energy and the possibilities to enrich, upgrade biogas. The use of methane rich gases like biogas and natural gas is today low in Sweden compared to major parts of the world.

Proteins are vital to all cells in the body. They consist of long chains of amino acids. To be able to study the amino acid composition of a protein it is necessary to hydrolyse it, followed by separation and quantification. When the protein is hydrolysed, in this case ß-lactoglobulin, the protein is divided into individual amino acids. The method that traditionally has been used to hydrolyse proteins takes 24-72 hours to complete.

A design methodology to mitigate timing problems due to long wire delays is proposed. The timing problems are taking care of at architecture level instead of layout level in this design method so that no change is needed when the whole design goes to backend design. Hence design iterations are avoided by using this design methodology. The proposed design method is based on STARI architecture, and a novel initialization mechanism is proposed in this paper. Low frequency global clock is used to synchronize the communication and PLLs are used to provide high frequency working clocks.

Proteins are vital to all cells in the body. They consist of long chains of amino acids. To be able to study the amino acid composition of a protein it is necessary to hydrolyse it, followed by separation and quantification. When the protein is hydrolysed, in this case ß-lactoglobulin, the protein is divided into individual amino acids. The method that traditionally has been used to hydrolyse proteins takes 24-72 hours to complete.

This is a graduation project in Innovation Management, which seeks to enlighten new theories within the major subject ? the multi?faceted innovation process.The reader is hereby invited to an insight in the more complex perspectives of these types of theories than what has previously been explained in simplified ways.We have conducted research on a company within the cleantech market; Cellkraft AB. The company develops and produces fuel cells amongst other products, which have emerged during their research and development in the fuel cell technology. Cellkraft works in a high?tech frontline market where innovation is key.