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928 Uppsatser om Peripheral arterial disease - Sida 37 av 62
Miljöekonomiska analyser av smog och luftföroreningsproblemen i Kina
Rapid economic development and urbanization has led to an improved standard of living for the Chinese people. Meanwhile, a series of environmental problems have also appeared and smog, in particular, has caused the Chinese people to realize how serious the situation is. Smog has seriously affected normal economic activities and people's everyday lives, resulting in financial losses, increased mortality and disease. How to handle the smog becomes particularly important. The purpose of this study is to describe and discuss the underlying causes of two sources of pollution, particulate matter and sulfur dioxide, as well as what drives individuals' and firms' environmentally destructive behavior.
Kromatografi av polära läkemedel och metaboliter med HILIC-teknik
The purpose of this project was to investigate if retention of polar compounds that are given to treat tuberculosis, diabetes, inflammatory bowel disease and childhood leukemia could be obtained with HILIC separation. By varying different parameters for different types of columns the compounds were analyzed with the aim of finding guidelines for future method optimizations. To perform these analyzes three different columns were tested ? ZIC-HILIC (silica-based with zwitterions), ZIC-pHILIC (polymer-based with zwitterions) and XBridge Amide (amide functions). The results were evaluated with selected quality measures.
Grb10 and developmental programming: evaluation of a maternal diet restriction model during gestation
This study was conducted at the University of Bath, UK, from September to December 2014 as part of an ongoing research project aimed at elucidating how the Grb10 gene might act as a mediator of long-term health effects (such as predisposition to obesity, diabetes, coronary heart disease and hypertension) caused by environmental factors during development. This phenomenon is known as developmental programming.
The purpose of this thesis was not primarily to answer any of the broader questions posed by this research project at large since this would require much more data than is reasonable to acquire over the course of a few months, but rather to evaluate the methods used in this project and reveal whether they are working the way they are presumed to. In the research project, which employs mice with the Grb10 gene knocked out as well as wild-type control mice, a dietary restriction model is utilized during gestation, which is supposed to generate offspring with lower birth weight and subsequent detrimental health effects in adulthood. This is supposed to be achieved by restricting the protein content of the pregnant mothers? diet to 9 % (as opposed to the control diet of 20 %) throughout gestation.
En jämförande studie mellan kreatininkoncentration i serum och GFR mätt med scintigrafi hos hund med misstänkt kronisk njursjukdom
Both serum creatinine and measuring GFR can be used to evaluate renal function in dogs suspected to have chronic kidney disease (CKD). Although high creatinine levels usually indicate renal disease, normal creatinine levels can be present in dogs with decreased renal filtration. Measuring GFR is generally believed to be the most accurate way of detecting decreased renal filtration and scintigraphy GFR using 99mTc-DTPA has been found to correlate well with the ?gold standard? inulin clearance method.When measuring GFR by scintigraphy, 99mTc-DTPA is injected intravenously and radioactive decay of technetium gives rise to gamma radiation, which is registered by a gamma camera. Pictures and curves of radioactivity in the kidneys are generated by means of a computer program.
Renal dysplasi hos hund :
Renal dysplasia is a developmental anomaly of the kidneys which is considered to be the primary lesion in juvenile progressive nephropathy, a condition leading to chronic renal failure in young dogs. It is defined as disorganised development of the renal parenchyma due to abnormal differentiation, and pathological lesions include persistent foetal structures, dysplastic tubules and cartilaginous and osseus metaplasia. The aetiology of renal dysplasia in dogs is still unknown, but possible causes are infection with canine herpesvirus, teratogenic substances or intrauterine ureteral obstruction. In some breeds renal dysplasia is a familial or inherited disease. Clinical signs of chronic renal failure, such as polyuria, polydipsia, vomiting, weight loss, anorexia, lethargy and anemia, usually appear before the age of 2 years.
Bortom Kultursponsring : En studie av samarbeten mellan teater och näringsliv
Bakgrund: Den svenska teaterscenen befinner sig i vad som tycks vara en ständig ekonomisk kris. De offentliga medlen räcker inte längre till, vilket har fått till följd att teaterinstitutionerna har blivit tvungna att söka sig nya inkomstkällor. Kultursponsring är en alternativ finansieringsform som har blivit allt vanligare. Vi vill undersöka kultursponsringens möjligheter för svensk teater. Syfte: Syftet med uppsatsen är att undersöka möjligheterna att gå bortom den traditionella definitionen av kultursponsring för att skapa ett helhetsperspektiv på utbyten mellan teater och näringsliv.
Ungdomars egen upplevda psykiska hälsa och skolsituation
The aim of this study was to describe non-surgical treatment options for the diseases mucositis and peri-implantitis found in present literature. The literature review also illustrates the effect of the treatment opptions on soft tissue with mucositis and peri-implantitis surrounding dental implants. The study reviews twelve scientific articles that have been processed from the aim of the study. The result shows six therapy options, Er:YAG laser, air abrasive, ultrasonic device, hand instruments, hand instruments in combination with antibiotics and hand instruments in combination with clorhexidin. The following methods are described according to how they are used and how they affect the soft tissue surrounding dental implants.
Sjukdomar i vallgräs : uppdatering av Faktablad om växtskydd -Sjukdomar i vallgräs (95 J)
In Sweden, 2011, ley was grown almost as much as cereals, which means that in terms of area, ley is an important crop. A lay can consist of either grass or grass combined with legumes e.g. clover. Forage grasses can be affected by many differ- ent diseases, some during the winter and some during the growing season. The diseases which do damage during the winter are called snow mold and can make large areas perish.
Assessing the ability of LARGE overexpression to prevent the development of muscular dystrophy
Duchenne Muscular Dystrophy (DMD) is a hereditary X-linked fatal disease that affects 1 in 3500 male births. It is the most common kind of muscular dystrophy in children and leads to death in the late teens or early 20s for many patients. The mdx mouse is a model of DMD that can be used to investigate experimental therapies. Overexpression of a glycosyltransferase, CT GalNAc, in mdx mice has been demonstrated to prevent the development of muscular dystrophy. Overexpression of another glycosyltransferase, LARGE, is currently being investigated as a treatment for another group of muscular dystrophies, the dystroglycanopathies.
In this study, we overexpressed LARGE in mdx mice in order to investigate its effect on the development of muscular dystrophy.
Effekter av motiverande samtal vid prevention av hjärt- och kärlsjukdom
Hjärt- och kärlsjukdom är den främsta dödsorsaken i Sverige. Majoriteten av dem kan förebyggas med hjälp av en livsstilsförändring, men för att göra det krävs motivation. En evidensbaserad metod som används för att främja motivation och livsstilsförändringar är motiverande samtal (MI). Syftet med litteraturstudien var att utforska vilka effekter MI kunde ha i sjuksköterskans prevention av hjärt- och kärlsjukdom. Resultatet visade att MI hade en varierande, men genomgående positiv effekt i att förbättra de levnadsvanor som är kopplade till hjärt- och kärlsjukdom.
Cueingstrategiers effekt på freezing och gånghastighet vid Parkinsons sjukdom : En litteraturöversikt
Parkinsons sjukdom drabbar 15 av 10 000 personer. Sjukdomen kan påverka gången genom freezing, då individen stannar upp och är oförmögen att fortsätta att gå. Detta är ett mycket besvärande symtom som kan behandlas med olika cueingstrategier. Även gånghastighet kan förbättras med hjälp av cueingstrategier. I den senaste litteraturstudien var evidensen för cueing oenig.
Botulism hos svenska hästar :
Botulism is a serious disease with high mortality that can affect horses. Due to this about 20-30 percent of the horses in Sweden are vaccinated against botulism.
The purpose of this study was to see how common botulism is in the Swedish horse population and to se if a connection between feeding with haylage and botulism could be seen. In addition to this, the study aimed to find how common vaccination against botulism is among Swedish horses and on what grounds the diagnosis botulism is made.
Medical records of horses being diagnosed with botulism at all the major large animal hospitals in Sweden between 1995-2005 were searched. In addition to this the database where general practitioners report their cases as well as the cases with botulism reported to the insurance companies were included.
The results of this study show that only 0,03 percent of the Swedish horse population has been diagnosed with botulism during the time period this study covers. In all the cases included in this study the diagnosis was made based on clinical signs and in none of the cases verification by isolating the toxin was possible.
In all cases where forage is noted in the journals the horse has been feed haylage which indicate that there is a connection between the use of haylage and botulism.
Three horses died despite being partially vaccinated against botulism type B which indicate that a correct vaccination has to be done before the horse get any protection or that the correct diagnosis was not botulism type B..
Förekomst av Giardia i symtomfria valpkullar :
The flagellate Giardia intestinalis has been known to cause diarrhea in both man and
dog. Results from epidemiological studies have indicated that transmission of the
parasite from dog to man is plausible even though that route of infection has yet to be
shown. Several international studies have shown that the parasite frequently occurs in
asymptomatic dogs. In Sweden the prevalence of Giardia in healthy dogs is not
known though. In this study, faecal samples were collected at two separate occasions
from 21 litters and 21 bitches showing no symptoms from the gastrointestinal tract.
The samples from each litter were pooled but the samples from the bitches were
analyzed individually.
Träningsinducerad lungblödning hos trav- och galopphästar
Träningsinducerad lungblödning, Exercise-induced pulmonary hemorrhage (EIPH), är ett
stort problem hos travare och galoppörer i hela världen. Det får anses klarlagt att mekanismen
bakom EIPH är så kallad stress-failure, utmattningsskador, i blod-gasbarriären vilket beror på
att hästarna har en respiration och cirkulation som ger extrema påfrestningar på denna sköra
struktur. En bidragande faktor till stress-failure tycks kunna vara att hypertension i
lungvenerna leder till att dessa remodelleras och förtjockas, vilket i sin tur leder till ännu
högre tryck i lungkapillärerna. Den här litteraturstudien handlar om hur inflammation i
lungorna kan ge upphov till EIPH. Inflammation finns med i problematiken runt EIPH både
som en bakomliggande faktor och som ett resultat av blödningen.
Investigation of tissue factor mRNA levels in human platelets using real-time PCR
Tissue factor (TF), a 47 kDa glycoprotein, is the initiator of the extrinsic pathway of blood coagulation and consequently of the upmost importance when damage to blood vessel occurs. The source of TF in circulation has been investigated. However, the source of TF is still not clear. One theory is that platelets express and increases the expression of TF after stimulation and the aim of our report was to investigate whether platelets really are a source for TF in circulation.Using specific primers for TF mRNA, platelets in plasma from healthy volunteers and from patients suffering from cardiac infarction were analyzed by using real-time polymerase chain reaction (PCR). Gel electrophoresis was performed after amplification of TF mRNA to verify the results.The samples were negative for TF when using real-time PCR and the few positive all had cycle threshold (Ct) values above 35.