Genotyping can be used to link genetic variation among individuals to certain diseases or conditions. Some known disorders and states that are dependent on single nucleotide polymorphism (SNPs) are lactose intolerance, venous thrombosis, hereditary hemochromatosis and the difference in sensibility among people to metabolise drugs.In this project a new kit, TaqManÒ Sample-to-SNP KitÔ for extraction of DNA and preparation of the extract for genotyping with real-time PCR and allelic discrimination, was evaluated. QIAamp® DNA Blood Biorobot® MDx Kit was used as the reference method.The purpose of the comparison was to find a method that makes DNA extraction from blood samples cheaper and faster, but with the same reliability as the reference procedure.The results of the evaluation showed a complete agreement of the genotype results between the methods tested, which means that the new method was as reliable as the reference method. The costs of reagents and material would be reduced with 52% if the new method is adopted, that alone would result in a cost reduction of 144 000SEK a year with a sample volume of 650 samples/month. The time for DNA extraction would also be reduced with the new procedure. .

The study is a case study of an activity, called the Oliven, that provides practice for people who are in the Arbetsförmedlingens Job- and development guarantee. The purpose of this study was to examine what it is in the Olivens activities, for people who are part of Phase 2 and 3 of the Job- and development guarantee, which, according to the participants, are working well and what works less well. We wanted to study how the participants perceive their work situation during the time that they participate in the activities. That is to gain knowledge of how the activities for people who are looking for work can be designed so that the participants can, from a salutogenic perspective, create a sense of coherence while they are participating.We have collected the empirical data through participant-observation and semi-structured interviews during two days. The analysis was made using the concepts ofcomprehensibility, manageability and meaningfulness.

This paper addresses the need to review the modern presentation of textile archaeology in museums. It is time to look at textiles in archaeology with new eyes. The reality behind archaeological textilestudy is holistic, embracing many different aspects of society. The presentation of textiles has in my opinion become old-fashioned. I will show in my paper that Jonathan Adams? `seven constraints´ model, developed for research on ancient ships, can also be applied to textile research.

This paper addresses the need to review the modern presentation of textile archaeology in museums. It is time to look at textiles in archaeology with new eyes. The reality behind archaeological textilestudy is holistic, embracing many different aspects of society. The presentation of textiles has in my opinion become old-fashioned. I will show in my paper that Jonathan Adams? `seven constraints´ model, developed for research on ancient ships, can also be applied to textile research.

Palliative care is founded on a holistic attitude, with the goal to alleviate suffering when a cure is no longer possible. Palliative care affirms life and regards dying as a normal process, providing possibilities of a quality time for the patient and family. Studies show that an increasing number of people choose to live the final phase of their life in their own home. A requirement for end of life care is an effective team work, where the nurse is responsible for more advanced care, and the caregiver?s provides the immediate care.

The number of elderly in Sweden is increasing due to improved living conditions and better medical care. It is important that society adapts to the increase and begins to work preventively to reduce the costs of the increase. An important aspect is the elderly accommodation, the cost of health care in specific accommodation is almost twice as high as those for ordinary housing. Therefore, it is important that we availability adapt dwelling to allow older people to live in ordinary housing for as long as they wish, instead of moving to assisted living before they need it. If we can fulfil the elder?s needs with home care instead, society can save a lot of money.In this report, three different forms of housing has undergone accessibility increases and been inventoried and analysed.

Äldre yrkesverksamma är en ökande grupp på arbetsmarknaden. Det är inte ovanligt att stereotypa uppfattningar kring denna grupp resulterar i åldersdiskriminering. Det är även känt att människor förändras, både till det bättre och sämre, genom åren och att detta påverkar individens yrkesutövande. Sex grundskolelärare intervjuades med syftet att beskriva och förstå hur de ser på åldrandet, pensionen, hur de upplever att de utvecklats under åren samt hur de upplever att omgivningen ser på dem. Erfarenheter ansågs vara det mest positiva med att vara äldre medan distansen till eleverna var det negativa.

To fence in pastures for sheep today is a major cost, especially because of the time required when using current methods. What takes most time is starting to fence off a new area, but to maintain a fence is also a continuous effort. The main function is to keep the sheep at the field.! !By interviewing and observing sheep farmers on how they work with fence today and what their problems was, I got a better understanding of the problem. Also looking at a number of other things like the context, statistics on sheep farming, laws and competition mapping gave a wider image. But the most important part in my research occurred when I talked to experts about sheep behavior.

This work is meant to show how memory can work within a smaller society when it comes to folklore and local history. What is remembered, how it is remembered and why it is remembered. Sprung from the older collections of folklore within the selected area - which is Glaskogen in western V?rmland - the purpose is to look at different types of memorizing and how it can work. The purpose is also to analyze some of the folklore from Glaskogen via narrative analyzing methods of Palmenfelt, Labov and Young, and also to understand Glaskogen from a cultural heritage perspective, looking at the valuation process and attitude towards the immaterial heritage.

The purpose of this essay is to investigate if the companies listed on Nasdaq/OMX Stockholm Large Cap use the earnings management phenomenon Big Bath Accounting to a greater extent when a change of management (CEO) is made.Management tends to use earnings management when there is a bonus plan linked to the result of the company. To gain maximum bonus the management will try to manipulate the result in a way that in a long term maximize their utility. Through the earnings management technique Big Bath the management is given the possibility to take one large cost as a one-time expend, even though the cost is supposed to run over several financial years. This, of course, within the legal framework. A big bath may occur when there is an impairment of goodwill, tangible and/or intangible assets or larger provisions for future expense, or both of them at the same time..

The projecting time in the construction industry needs to become more efficient toshorten the amount of time it takes to project a build. One of the North's leadingconstruction company NCC constuction Sweden AB has developed a form ofcollaboration called ?NCC project studio? that they use in some projects today.My thesis consists in bringing forth the most important aspects of the collaborationform called NCC project studio. The point of this is to use my thesis to help thecompany develop a quality document that can assist them when starting collaborationbased on NCC project studio in the future.The conclusion of my thesis was that much of the focus needs to be on explaining tothe participants what NCC is aiming to gain from working with the NCC projectstudio and also which important parts that needs to be worked on..

The study is based on a new approach on how Swedish healthcare is supposed to be controlled and organized. There is a renowned administration problem within Swedish healthcare, which seems to be an obstacle to exploit the resources to the fullest. The latest venture within the healthcare system is patient involvement, where the patients become co-producers of their own care, which aims to both improve and make healthcare more efficient. A few wards in Sweden have implemented this new approach whereupon the study intends to discuss the effectiveness and efficiency in some of these.The study is restricted to three wards, whereof two of these are inpatient wards and the other one is an outpatient ward, within the medical clinic in Jönköping County Council, which has implemented the patient involvement approach in their daily work. The methodology for this study is qualitative in its nature where a time study of personnel time allocation and supplementary interviews with managing nurses on the wards have been conducted.

The purpose of our study was to examine how missing children are portrayed in media. We wanted to see if there are any recurring story patterns and characters in the texts. We also wanted to examine how the relationship between children and adults are framed and which comprehensive view of children is mediated in journalistic texts.Our questions were: how do Swedish newspapers write about missing children? Which narrative pattern are there in the texts? How are children and adults represented in the texts? What relationship between children and adults are made visible in the texts? What a comprehensive approach to children is constructed in the texts?For this study, we used the media discourse, theories of representation, stereotypes and characters. And theories of narrative, dramatic turns and opposites.We chose to make three case studies in which children suddenly disappeared, the case of Bobby Äikiä, the case of Engla Höglund and the case of Sebastian Hedman.

This essay is called What kind of history? and is about how history teachers think when they chose what to teach about and why. In the curriculum there are no guidelines about what substance you have to teach about. This gives the schools and teachers a big freedom. At the same time there is a kind of informal canon which says that it is the European perspective that is the important one.

This study aims to measure the effect of accounting conservatism and to identify thebusiness activities causing firms to undervalue owners? equity. To estimateaccounting conservatism, we have followed the hypothesis that no firm over time cangenerate a return greater than its cost of equity, i.e. CAPM. Thus, if a firm in factgenerates an excess return over time, we assume that the excess return is an estimateof accounting conservatism within that firm.The hypothesis originates from the corporate valuation model ?Economic ValueAdded®? which tries to adjust for accounting bias.