The use of intramuscular injections of procaine penicillin G (bensylpenicillin procaine) in the horse is now and then associated with acute adverse reactions (penicillin-chock). The etiology is not yet clearly understood, but the theories are several. One possibility is that it can be caused by procaine toxicity. Procaine penicillin G is a salt which is quickly dissolved in plasma. Procaine is then metabolized by plasmaesterases to non-toxic Metabolites, p-aminobenzoic acid (PABA) and diethylaminoethanol.

Ethanol produced from lignocellulosic biomass has the potential to become a promisingalternative to gasoline. In this work the simultaneous saccharification and fermentation (SSF)technology was applied for ethanol production from hardwood with focus on cell growth,ethanol production and contamination.The SSF was performed at PH 5.5 and 35°C for different suspended solid concentrations(8%, 10% and 12%) of pretreated birch slurry which contained 16 % total suspended solids.Two different hexose fermenting yeast strain (Ethanol Red) and pentose fermenting yeaststrain were used.Quantifying the concentration of chemical components and Metabolites in the fermentationmedium demonstrated that glucose and xylose are the major fermentable sugars in the slurry.The higher load of slurry (12%) represents a higher content of carbohydrates and potentiallyhigher end concentration of ethanol. Moreover, more lactic acid is produced with the lowerload of slurry (8 % or 10 %), presumably due to a result of a less inhibitory environment forbacterial growth. In this context, acetic acid sticks out as the most important inhibitor withconcentrations of 15.2 and 12.5 and 9.7 g/l respectively in the 12 %, 10 % and 8 % (ofsuspended solids) trials. Using pentose fermenting yeast may lead to higher ethanolproduction, lower xylose uptake and lower lactic acid formation.

This study has focused on testing the following two hypotheses:? Pest resistant plants have higher levels and/or several different kinds of secondary Metabolites. ? Induced defensive systems in resistant plants are activated more rapidly than those of susceptible plants. As a background for the test of the hypotheses a short literature study was performed concerning plant defensive mechanisms in Arabidopsis thaliana.

The present study discusses the metabolism of ethanol in the human body from the ingestion of ethanol to the excretion of its break down products water and carbon dioxide. Ethanol is a small molecule, soluble in water as well as in organic solutions. It is quickly distributed to every section in the body, where it exerts a direct toxic effect on the cells. Ethanol cannot directly leave the body efficiently so it needs other metabolic pathways. The molecule is metabolized by oxidation, predominately in the liver.

The presence of cystic ovarian follicles represents an important ovarian dysfunction and is a major cause of reproductive failure in dairy cattle. A cystic ovarian follicle is a persistent follicular-like structure on one or both of the ovaries. It is at least 2,5cm in diameter and it has to persist for at least ten days while a corpus luteum is missing. There are two kinds of cystic ovarian follicles, those who have a progesterone production and those who have not. A clear definition for this condition is lacking, probably because the heterogeneity of the clinical signs and the complexity of the disorder.

Cuttings of Lonicera xylosteum L. were treated with willow extract to study the response in rooting capacity. The extracts were prepared by mixing chopped pieces of Salix x smithiana Willd. with water in a warring blender. The investigation comprised 2 types of salix extracts based on differences and dynamics between twigs in winter dormancy and twigs with new shoots. To explore the rooting response, three tests were made.

Sahlgrenska Academyat University of GothenburgDepartment of internal medicine and clinical nutritionAbstractTitle: Does omega-3 mitigate skin symptoms in psoriatic patients? ? A systematic review about the effects of supplementationAuthor: Anita Borgmästars and Sara LinderSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 22, 2012Background: Psoriasis is an inflammatory skin disease with high prevalency. Its treatment is time-consuming and associated with many side effects. Therefore alternative forms of treatment, among them omega-3 supplementation, have been investigated. Omega-3 is a family of polyunsaturated fatty acids whose Metabolites participate in the regulation of inflammatory reactions in tissues and may therefore have a positive effect on skin symptoms in patients with psoriasis.Objective: To determine if omega-3 supplementation has a beneficial effect on skin symptoms in psoriasis compared to omega-6 supplementation by rating the evidence quality in available studies.Search strategy: The literature search was conducted in the databases PubMed, Scopus and Amed.

AbstractMycotoxins are secondary Metabolites produced by filamentous fungi. Moulds producing mycotoxins grow on various crops that are used as horse feeds. Since the treatments of mycotoxin poisoned horses are limited it is important to prevent production of mycotoxins in feed. The major mycotoxin producing moulds in horse feeds are Fusarium spp., Penicillium spp. and Aspergillus spp.

Denna litteraturstudie behandlar förgiftningar hos hund med begränsning till förgiftning orsakat av etylenglykol och råttgift. Vilket av dessa ämnen som är farligast och hur stor risken är att en hund får i sig dem är två frågor som kommer att undersökas. Det kommer att tas reda på mer om hur det ligger till med etylenglykolets påstått söta smak. Syftet med studien är även att utreda om allmänhetens medvetenhet behöver ökas om vanliga potentiellt farliga ämnen för våra husdjur. Att hundar utsätts för förgiftningar är inte ovanligt och antalet försäkringsfall där hundar blivit förgiftade har ökat mellan 2010 och 2014. Om en hund utsätts för ett giftigt ämne är det mest optimala att så tidigt som möjligt hindra giftet från att absorberas från gastrointestinalkanalen och därmed hindra att det gör någon skada.

AbstractMycotoxins are secondary Metabolites produced by filamentous fungi. Moulds producing mycotoxins grow on various crops that are used as horse feeds. Since the treatments of mycotoxin poisoned horses are limited it is important to prevent production of mycotoxins in feed. The major mycotoxin producing moulds in horse feeds are Fusarium spp., Penicillium spp. and Aspergillus spp.

Tramadol är en centralt verkande opioid vars smärtlindrande effekt främst anses bero av två mekanismer. Dels en svag affinitet för ?-receptorn men även en inhiberande effekt på återupptaget av och en stimulerande effekt på den cellulära frisättningen av serotonin och noradrenalin. Till strukturen liknar tramadol kodein och morfin men affiniteten för ?-receptorn är 10 gånger lägre jämfört med kodein och 6000 gånger lägre jämfört med morfin.