A patient simulator for testing anaesthesia machines has been developed at Maquet Critical Care AB, to reduce costly and time-consuming experiments on animals. The device simulates human lungs regarding lung dynamics and volume, uptake of anaesthetic agents and the production of carbon dioxide, heat and moisture. Further demands on the simulator are durability and size; the device shall be compact enough to be moveable.The resulting simulator fulfils the requirements and enables better repeatability and ability to test extreme cases than experiments on animals do.Uptake of the anaesthetic agent is achieved in a active carbon filter and controlled by regulating the flow. The flow is created by a regenerative blower and controlled using a proportional valve. The uptake can be set by the user or by a simple uptake model modified to recursively handle changes in the concentration of anaesthetic agent.Carbon dioxide is fed into the system from a tank by a mass flow regulator.

Background Atelectasis is a commun respiratory complication related to general anesthesia and may contribute to pneumonia and acute respiratory failure. Atelectasis apear within 10 minutes after anesthetization and occur in 90% or more anesthezied patients regardless of age and gender. The aim of this study was to indentify if there are any evidence for which methods are ultimate or are most efficacious to reduce and prevent the formation of atelectasis.                                                                                                          Methods This study is a descriptive litterature study where 28 scientific studies have been indentified for review and analysis.                                                                                                               ResultsThe use of 100% oxygen during the induction of anesthesia favors the developement of atelectasis. This can be prevented by preoxygenation with oxygen content of 100% combined with a PEEP of 6-10 cmH2O. When free airway is secured, oxygenation with 100% was found to be unnecessary.

SammanfattningSyfte och frågeställningarSyftet var att studera sambandet mellan GIH:s Gångtest och bestämd maximal syreupptagningsförmåga (VO2max). En av frågeställningarna var om GIH:s Gångtest är ett alternativt test för att försöka predicera maximal syreupptagningsförmåga hos friska fysiskt aktiva unga vuxna.MetodI studien ingick 45 fysiskt aktiva personer (26 kvinnor och 19 män) i åldrarna 19-28 år. De två genomförda testerna är GIH:s Gångtest (ett 6-minuters gångtest) och bestämning av maximal syreupptagningsförmåga med löpning på ett motordrivet rullband.GIH:s gångtest är ett shytteltest där testpersonen (Tp) går fram och tillbaka på en 50 meter lång sträcka och runda två koner. Tp får gå denna sträcka så många gånger som möjligt under 6 minuter. Vid testets slut mättes maximal gångsträcka, puls och ansträngningsgrad.Testet för att bestämma maximal syreupptagningsförmåga utfördes med löpning på ett motordrivet rullband.

Bakgrund: Träning medför hormonella förändringar och anpassning av vävnader. Under kvinnans menstruationscykel fluktuerar halten könshormoner. International Organization for Physical Therapy in Women?s Health (IOPTWH) anser att vårdutbildningar på grundnivå bör inkludera kunskap kring kvinnans specifika fysiologi. Detta bör tas hänsyn till och inkluderas i sjukgymnastens arbete, rehabilitering och träning av kvinnliga patienter.

Bakgrund: Styrketräning kan öka muskelstyrka och muskelmassa för såväl otränade motionärer som vältränade elitidrottare. Teorierna kring effekterna av olika typer av styrketräning baseras i stor del av forskning på otränade individer. Syfte: Syftet med denna studie var att undersöka vilken form av styrketräning som ger en frisk, redan vältränad individ störst ökning i maximal styrka och/eller muskelmassa. Metod: Studien är en litteraturöversikt med granskning och bedömning av studier som avhandlat olika styrketräningsformer på vältränade individer med >2 månaders erfarenhet utav styrketräning och som utvärderat resultatet i maximal styrka eller muskelmassa. Artiklar söktes i databasen PubMed.

Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. Eight Swedish high-health domestic pigs were randomly assigned to be either controls or made diabetic using streptozotocin (STZ). The experiment proceeded during eight weeks, starting with an acclimatisation period. Once the pigs had been socialised they underwent surgery for the insertion of a jugular vein catheter, allowing induction of diabetes with STZ, intravenous (i.v.) injections and stress-free blood sampling. Development of diabetes was confirmed by clinical examinations, blood glucose values and insulin-staining of pancreatic sections post mortem. The diabetic pigs were insulin treated and responded well.

Yeast and Clostridia is a problem in silage for farmers as contaminated silage may result in poor animal health and milk quality. Clostridia can produce toxins that, when consumed, acts as neurotoxins, it may also cause blown cheeses if the Clostridia contaminates milk. The purpose of this study was to investigate the cause, effect and interaction of yeasts and Clostridia in silage. Clostridia are microorganisms which are strictly anaerobic and consume carbohydrates and protein in the silage. Yeast is a fungus that is facultative aerobic and feed on carbohydrates in the silage.

SammanfattningSyfte och frågeställningar. Syftet med denna studie var att på äldre personer studera olika fysiologiska parametrar före och efter en period på åtta veckor med styrketräning som utförs tre gånger i veckan. Frågeställningarna var: Hur påverkas statisk och dynamisk maximal styrka i främre lårmuskulaturen av styrketräning? Är det någon skillnad i resultat mellan koncentrisk och excentrisk styrka i lårmuskulaturen före och efter styrketräningsperioden? Är det någon skillnad i förändring mellan benstyrka uppmätt med isokinetisk teknik jämfört med uthållighetsstyrka och ett kort funktionellt benstyrketest? Hur påverkas maximal syreupptagningsförmåga registrerad via submaximalt cykeltest respektive vid pyramidtestet av träningsperioden?Metod. I studien deltog 20 generellt ej påtagligt aktiva män och kvinnor i åldrarna 66-79 år.

Background: Myocardial infarction is the most common individual disease among people in the west world. In Sweden there are over 50 000 women and men who get myocardial infarction every year and about 40 % of them dies. Exercise training is one part of cardiac rehabilitation and since 1980 Sweden use the guidelines from that time. Aim: The aim was to review exercise-training modalities in cardiac rehabilitation after myocardial infarction and the physiologic- and psychological effects. Method: Facts were obtained by searching through the database PubMed for articles published from 1994 and ten years forward.

The purpose of this work has been to explore what ecosystem services a small green area in an urban environment can offer and whether specific trees can be used to maximize regulatory ecosystem services in a cultural-historical environment. Additionally, it investigates whether there is any difference in ecosystem services depending on whether these trees, or trees that better fit into the cultural-historical environment, are used. Through simulations and comparisons with existing trees in Pommerska tomten, Mariestad, Sweden, a pocket park within a national interest area, different hypothetical tree planting options are analyzed and evaluated. To measure ecosystem services, the website My-Tree, developed by the US equivalent of the Department of Agriculture, was used. By inputting data about the tree, such as location, species, vitality, stem diameter, and solar exposure, My-Tree calculates some of the ecosystem services the tree provides.

Abstract The accident in 1986 at the nuclear power station in Chernobyl, Ukraine, dispersed radioactive cesium over large areas of Europe. The half life of 137Cs is 30 years and this radionuclide also behaves like potassium, which means that it can easily be taken up by the vegetation or be adsorbed in to the structure of clays, principally illitic clays. When radiocesium decays ionizing radiation is emitted, which is harmful to humans that are exposed, either directly or indirectly through food intake. It is there-fore important to know what happens to the cesium that is dispersed into the environ-ment. In this project a simulation model was constructed to simulate the adsorption and transport of radiocesium in the soil and plant uptake.

The EU Water Framework Directive has led that management follows the boundaries of natural catchments.The Swedish waters suffer from a nutrient overload that originates mainly from diffuse sources such as agriculture and the subcatchment of Hackstabäcken in Vallentuna Kommun, just north of Stockholm, has been chosen for this study because of its high nutrient load and because it has undergone obvious changes in land use through the years.In this study, the land use in 1902 is compared with the land use in 2011 in order to investigate if it has influenced the ability of the landscape to produce ecosystem services related to nutrient removal. These services will continue to be produced as long as the system is stable and resilient, but when landuse changes and manure from horses increases it will lead to disturbances that can convert a system from one regime in to a completely different one. That will result in loss, or degradation, of ecosystem services such as denitrification, phosphor sedimentation and adsorption, vegetation uptake and infiltration.The results of this study are based upon area calculations of landuse from old maps from 1902 and 2011. Through these maps it becomes clear that the forests in Hackstabäcken, has increased with 170 ha together with an urbanization of 311 ha, at the same time as wetlands and arable land has diminished and lakes has suffered from reductions. Wetlands have been reduced with 76 ha and the ones remaining are of insufficient quality from a nutrient removal perspective.Data from 1902 and 2011 regarding number of horses and bovines indicated a decrease in bovines and an increase in horses.

SammanfattningIntroduktion: I dagens arbetsliv och samhälle har individen blivit allt mer stillasittande och minskat mängden motion med risk för sämre kondition trots att detta är en känd riskfaktor för sjukdom och nedsatt arbetsförmåga. Syftet med denna studie var att studera konditionsnivån hos kontorsanställda i förhållande till BMI, kön och ålder.Metod: En kvantitativ tvärsnittsstudie har genomförts baserad på data från hälsoundersökning där BMI, kön, ålder och konditionstal undersöktes. 100 personer deltog i studien, varav 33 kvinnor och 67 män i åldern 25-63 år.Resultat: De kontorsanställda hade en god syreupptagningsförmåga på i genomsnitt 37,3 ml/(kg x min) och låg över det rekommenderade konditionstalet 35 ml/(kg x min) för kontorsarbetare. Kvinnorna i gruppen hade bättre konditionstal än männen. Medelålders kvinnor (41-50 år) hade något lägre konditionstal än yngre (25-40 år)och äldre kvinnor (51-63 år).

In the production of pulp, paper and cardboard, a large amount of water is used daily. The water has to be purified in the internal purifying plant before it reaches the receiving body of water. In the biological purifying stage at the Stora Enso Skoghall mill, an aerated basin is used where the microorganisms, using oxygen, oxidize the organic material to carbon dioxide. The air is pumped from the bottom of the basin and the oxygen can then be transported from the air bubbles to the water through diffusion. The problem with aeration of waste water from the forest industry is that wood residues, such as fatty acids, are making the transport of oxygen in water more difficult.

Obese horses with insulin resistance are often also afflicted with laminitis. Horses with these symptoms are given the diagnosis equine metabolic syndrome (EMS). Signs of insulin resistance are excessive accumulation of adipose tissue on the neck, around the withers and on the dorsal area of the hindquarters. Insulin resistance means that the function of insulin is defective and does not stimulate glucose uptake by the cells in the body in the correct way. This will result in an increased insulin release.