System based models of plants rely on descriptions and assigned functions of genes, and currently 50% of the genes in Arabidopsis thaliana has either no assigned function or a function based on homology only. Mitogen activated protein kinases (MAPK's) are key players in cell signalling and are conserved among eukaryotes, though their targets are highly diverse. A recent study has described a small Arabidopsis protein (80), without homology to any described protein, as a phosphorylation target of the MAPK's MPK3/6. Further work established ?-glucan phosphorylase (PHS) as interacting with 80 and described a delayed senescence phenotype for 80 knock-out plants.

Scrapie is an infectious neurologic disease in sheep caused by prions, corresponding to transmissible spongiform encephalopathies (TSEs) in other species. The prion is presumably constituted of PrPSc, the misfolded form of the normal endogenous prion protein, PrPC, which is found in practically all cells in the body. PrPSc can induce a conformational change in PrPC and misfold it as an imprint of itself; this is how prions amplify and spread. The process of conformational change is poorly understood and there might exist intermediate forms between PrPC and PrPSc. Bioassay using mice has traditionally been the golden standard in prion studies but is limited by cost and time.

The work covered in this report includes a literature study of the diesel dual fuel technology(hereinafter referred to as DDF). The literature study covers earlier work that has been doneregarding the use of compressed natural gas (CNG) and diesel in a DDF system. Moreover a onecylinder research diesel engine was fitted with a CNG fuel system for experimental testing. Theinstallation of the engine and the test cell is described. Results from the tests are presentedcovering emissions, heat release and pressure traces from the DDF-concept.During the literature study it was found that most research was related to heavy duty dieselengines.

The aim of the project was to investigate if Swedish rodents, brown rat (Rattus norvegicus), house mouse (Mus musculus), wood mouse (Apodemus spp) and water vole (Arvicola terrestris) captured in pig herds and in urban areas, constitute a reservoir for pathogenic Leptospira spp. Under Swedish conditions leptospirosis gives rise to reproductive disorders in pigs and symptoms of flu in humans. It has long been established that rodents are chronic carriers of pathogenic leptospires in their kidneys, and can spread the bacteria with urine. The old nomenclature of serovoars is still in use, but a new system of genetic classification has developed and today the genus Leptospira contains 17 species. There are several diagnostic test developed for leptospirosis.

The aim of the project was to investigate if Swedish rodents, brown rat (Rattus norvegicus), house mouse (Mus musculus), wood mouse (Apodemus spp) and water vole (Arvicola terrestris) captured in pig herds and in urban areas, constitute a reservoir for pathogenic Leptospira spp. Under Swedish conditions leptospirosis gives rise to reproductive disorders in pigs and symptoms of flu in humans. It has long been established that rodents are chronic carriers of pathogenic leptospires in their kidneys, and can spread the bacteria with urine. The old nomenclature of serovoars is still in use, but a new system of genetic classification has developed and today the genus Leptospira contains 17 species. There are several diagnostic test developed for leptospirosis.

The aim of the project was to investigate if Swedish rodents, brown rat (Rattus norvegicus), house mouse (Mus musculus), wood mouse (Apodemus spp) and water vole (Arvicola terrestris) captured in pig herds and in urban areas, constitute a reservoir for pathogenic Leptospira spp. Under Swedish conditions leptospirosis gives rise to reproductive disorders in pigs and symptoms of flu in humans. It has long been established that rodents are chronic carriers of pathogenic leptospires in their kidneys, and can spread the bacteria with urine. The old nomenclature of serovoars is still in use, but a new system of genetic classification has developed and today the genus Leptospira contains 17 species. There are several diagnostic test developed for leptospirosis.

Today when new and harder demands on CO2 emissions are developed, vehicle manufacturers must work to develop new engine solutions to new kinds of fuels to replace fossil fuels. A fuel that could be applied is hydrogen. When hydrogen is combusted only water vapor occurs. Hydrogen is known to be explosive and flammable. These properties are both good and bad for combustion.

Intramuscular injections to cats can generate strong reactions in some individuals while reactions of the same extent, according to the author, not always are recognized when using the subcutaneous route. The reactions are probably caused by fear, stress and/or pain. When the injection can generate pain one has to take that into account, which can be a limitation in treatment. It is well known that injections generate pain, but knowledge about the cause and processes of the injection-associated pain is limited. This is mainly due to the difficulty in finding objects to study pain on, high cost of use of laboratory animals and difficulty to obtain objective measurements. Although there is evidence that there may be a local muscle injury by intramuscular injection, it is not always that the extent of damage is related to the pain experienced. Facts about the causes of injection-associated pain have been studied in a literature review.

Brominated flame retardants (BFRs) has for many years been used in products to reduce their flammability, mainly in electronic products, textiles and construction materials. In 2003, Sweden imported 300 tons of brominated flame retardants. Leakage of these compounds has polluted natural environments. Fishes has shown increased contents of these substances, especially fat fish, since brominated flame retardants tends to accumulate in fatty tissues. They are also regarded as persistent and that gives them the ability to travel long distances. What also is really scary is that increased levels of brominated flame retardants have been detected in human breast milk. The knowledge of the brominated flame retardants is limited and not so much research has been done in this field. There are many reasons though, to keep the research going. Partly their structural resemblance to well-known toxics as PCB, but also their ability to accumulate in biological systems and enrich in food chains. In which way they affect humans we really don?t know yet.

Syfte: Uppsatsens huvudsyfte är att kartlägga och beskriva hur modebranschen förhåller sig till fenomenet kopiering. Genom att kategorisera olika attityder gentemot kopiering samt de aktörer som står bakom attityderna, analyseras även varför vilka aktörer har specifika attityder kopplat till fenomenet.Design/Metod/Ansats: Uppsatsen presenterar, med hjälp av kategorier, de attityder och aktörer som är representerade i debatten om kopiering. Ett urval har gjorts i fråga om vilka media och texter som ska analyseras i ramen för studien. Dessa texter har sedan analyserats så till vida att kategorier av attityder kunnat identifieras i texterna. I ett andra steg har de aktörer som står bakom de identifierade attityderna kategoriserats.

Diabetes mellitus is an endocrine disorder affecting a range of different mammals, including dogs, cats, horses and humans. Worldwide, 347 million people have diabetes, and the disease is an increasing burden on the world?s poorest countries. The disease is characterised by chronic hyperglycaemia and afflicted individuals experience increased thirst, polyuria and weight loss, sometimes despite increased appetite. Diabetes mellitus is either insulin dependent or non-insulin dependent.

Den ökande konkurrensen inom fordonsindustrin har tvingat företag att öka flexibiliteten samt att använda resurser och information mer effektivt. Fordonsindustrin är förknippad med linjetillverkning och det är vanligt att modula system används för att hantera djupa produktsortiment. CKD-verksamheter hanterar komponenter och moduler som levereras till internationella kunder där de monteras ihop till slutprodukter. CKD-verksamheter är i behov av likadana komponenter och moduler som tillverkningslinjerna och detta leder till att komplexa materialflöden uppstår. Studien har genomförts på Scania i Södertälje som bland annat tillverkar bussar och lastbilar.

International Marine Group, IMG AB, was established in year 2000, and became the parent company of the three sister companies, Momec AB, Isolamin AB and Premec AB. The IMG ? group supplies complete marine/offshore interior accommodation and tailor-made system supplies to the Building/Industrial sector. With a starting point to develop IMG AB?s logistic and distribution the company has decided to survey the present logistic at their subsidiaries, mainly concentrated on the goods for delivery.