Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

Background: Myocardial infarction is the most common individual disease among people in the west world. In Sweden there are over 50 000 women and men who get myocardial infarction every year and about 40 % of them dies. Exercise training is one part of cardiac rehabilitation and since 1980 Sweden use the guidelines from that time. Aim: The aim was to review exercise-training modalities in cardiac rehabilitation after myocardial infarction and the physiologic- and psychological effects. Method: Facts were obtained by searching through the database PubMed for articles published from 1994 and ten years forward.

In the dog-human relationship humans are the ones who provide the dog with safety and comfort. Ainsworth's Strange Situation Procedure (ASSP), which was originally developed in humans to study the relationship between mothers and infants, has been modified to investigate the emotional bond research dogs have to a familiar person. Twelve research dogs were tested to investigate whether the dogs performed any behaviours indicating a secure-base effect, such as more exploration and play in the presence of a familiar person and proximity-seeking behaviours when this person is or has been absent. In the ASSP the dog enters a room with a familiar person, is introduced to a stranger, is left alone for a short period of time and experiences moments of separation and reunion. A second variation of the ASSP was added where the familiar person was replaced by another, to the dog, unfamiliar person.

Annedal is a brand new neighborhood in the Bromma part of Stockholm. The neighborhood construction has now reached its halfway point. When finished, 5000 people are estimated to live in Annedal. The focus for the new area is variation. Both housing co-operatives and rented apartments have been built and more are under construction.A study about the valuation of town quality in the Stockholm region was produced by the Stockholm County Council in 2011.

Hjärtsvikt är ett tillstånd då hjärtfunktionen försämrats och cirkulationen inte förser kroppens alla organ med tillräckligt stort blodflöde. Vid hjärtsviktsbehandling är loopdiuretika viktigt för att behandla ödem då det verkar vätskedrivande. Torasemid är ett loopdiuretika som har visats vara effektivt och bra tolererat. I flera studier har effekterna jämförts mellan torasemid och furosemid varvid många betydelsefulla och förmånliga effekter har observerats för torasemid. Syftet med litteraturstudien var att ta reda på om torasemid kan vara ett bättre alternativ till furosemid vid hjärtsviktsbehandling, om torasemid bör kombineras med spironolakton, om furosemid borde sluta användas och varför torasemid inte används i större utsträckning vid hjärtsviktsbehandling. Slutsatsen av litteraturstudien är att torasemid borde användas istället för furosemid vid behandling av hjärtsvikt, vilket grundas på de fördelar som har redovisats i genomförda studier.

The development in photogrammetry has created possibilities for new methods in aerial images acquisition. Remotely-controlled imaging from an unmanned helium zeppelin is a new and relatively unexplored acquisition. The purpose with this degree project is to evaluate the accuracy of this kind of low-height photographing system, a task given from the consultant company WSP, in Sweden. Landbadet in Uddevalla municipality was chosen as a test field for the zeppelin. Seventeen images distributed over three strips were acquired from the flying height of 80 m.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

Uppsala County has ambitious environmental aims for the planned residential area inÖstra Sala backe. In this thesis different energy sources have been evaluated todetermine which system that would be most favorable given currently availableinformation about the project. Planned energy usage has been divided into tap waterheating, space heating and power. Three base case scenarios were made with districtheating, small scale bio fuel and heat pump. Solar power and solar heating were thensimulated and the production from the two could individually be deducted from theenergy need in the base cases, constituting 9 different scenarios.

Dagens moderna e-samhälle har inneburit stora förändringar för den vanliga individen. En av de största vardagsförändringarna är digitaliseringen av kommunikation. Analoga brev ersätts i allt större mån av digitala e-mail och analoga tidningar samt flygblad digitaliseras eller förmedlas genom hemsidor. Många är nog ense om att detta är något positivt. Att den tekniska utvecklingen bör främjas snarare än att motverkas.

SAMMANFATTNINGI Sverige drabbas ca 10 000 personer av hjärtstopp utanför sjukhus varje år. Överlevnaden är låg, men på senare år har åtskilliga insatser gjorts för att förbättra dessa siffror. Bland annat har man börjat utbilda brandmän, säkerhetsvakter och taxichaufförer i hjärt-lungräddning med defibrillator och numer är hypotermibehandling en vedertagen metod för att skydda den ischemiskt skadade hjärnan. Trots detta kan dessa patienter drabbas av funktionsnedsättning på grund av den syrebrist i hjärnan som ändå uppstår till följd av hjärtstoppet. Det är viktigt att ha kunskap om hur dessa patienter mår och klarar av sin vardag sedan de lämnat sjukhuset, för att kunna ge det stöd de behöver för att kunna återgå till ett så normalt liv som möjligt.Syftet var att beskriva livssituationen hos patienter som drabbats av hjärtstopp med fokus på livskvalitet, kognitiva funktioner och ADL.Forskningsöversikt valdes som metod för att få en samlad bild över aktuellt kunskapsläge inom detta problemområde.

This essay presents and discusses a study that was performed in a multicultural school, where the teachers, since August 2004, have obtained internal training in how to work with language development. The objective with this essay is to investigate how the connection between language development and the development of knowledge can be understood and apprehended by teachers working in this school, and furthermore, to show how a language developing way of work can be accomplished in the teachers daily work.Moreover, I have studied which objectives and strategies, the three language developers in charge of the training of the teachers, have concerning this work, furthermore I have looked into if these objectives and strategies differ from what the teachers understand and practically perform.Pauline Gibbons book, Stärk språket, stärk lärandet (2006), has become a base for this school?s work when it comes to language development. Gibbons presents theories and practical exercises which have their origin from Vygotskij, Halliday and Cummins. Their theories have also become my theoretical base in this study.I have made qualitative interviews with four teachers working in this school, and with one of the language developers.

När du arbetar med teckensnitt, vare sig du skapar ? eller helt enkelt väljer ett teckensnitt, finns det konsekvenser till följd av skapandet och/eller valet. Läslighet och läsbarhet ligger i hjärtat av teckensnitts utformning ? men principerna kring läslighet och läsbarhet är flexibla och kan komma att bortses ifrån, beroende på den tänkta kontexten för teckensnittet. Ett grepp om historiken bakom användningen av vissa teckensnitt, såväl som kunskap om de möjliga associationer de kan väcka är också av stor betydelse när man arbetar med teckensnitt.

This thesis was performed at Scania?s purchasing department of non-automotive products inSödertälje, Sweden during spring 2007. The management of the purchasing department ofnon-automotive products believe that their internal customers might not have fullunderstanding of what the purchasing department does. This is a problem because the internalcustomers might not use the contracts negotiated by the purchasing department or they mightnot involve the purchasing department when making purchases.The purpose of this thesis is to examine if and how the internal customers? perception deviatesfrom the purchasing department?s perception regarding the task of the purchasing department.And also to create a communication package with the purpose of increasing the internalcustomers understanding of what the purchasing department does.

Syfte: Identifiera recidivmönster hos glioblastom samt studera betydelsen av erhållen stråldos beträffande uppkomsten av recidiv.Metod: 50 patienter som strålbehandlats för glioblastom valdes ut till studien och deras magnetkamerabilder från uppföljningen jämfördes med behandlingsplanen frånstrålbehandlingen. Lokala, marginella eller distala recidiv identifierades baserat på om recidivet låg innanför, tangerade eller låg helt utanför PTV (planning target volume). De marginella delades in i två grupper, de som hade en fysisk koppling, connex, till GTV (gross tumor volume) och de som inte hade det. Vidare lästes erhållen stråldos i recidivet ut från strålbehandlingsplanen.Resultat: 35 stycken patienter hade fått recidiv på 42 unika lokaler. Av dess 42 recidiv var 66,7 % (28 stycken) lokala, 9,5 % (4 stycken) marginella med connex till GTV, 19 % (8 stycken) marginella utan connex till GTV och slutligen 4,8 % (2 stycken) distala.

The purpose of this thesis is to study whether there is a demand for sawn wood products of large dimensions and planed goods among Wallnäs AB:s customers. The thesis consist of two main parts, one survey among Wallnäs present customers and another one which purpose is to increase Wallnäs customer base. Finally there is a chapter that describes what properties the raw material has to have in order to produce the demanded products. The survey to the present customers was conducted through a questioner. A sample of those who stated an interest for either sawn wood products of large dimensions or planed goods, were later contacted for a telephone interview. To reach out to new customers, relevant companies has been identified through the Swedish Trade Councils data base and through the member list of the Timber Trade Federation.