Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly breast cancer and ovarian cancer.

The aim of this literature review was to suggest suitable index traits to use in the Swedish Sheep Recording Scheme for fertility and maternal traits. Since fertility and some of the maternal traits are not normally distributed advanced methodology is needed to calculate genetic parameters. Breeding is a tool to improve the economy of the farm and for the selection of breeders estimated breeding values (EBV) for important traits are of high value. In sheep breeding both lambs born and lambs weaned should be taken into consideration as well as the ewe?s maternal ability, which includes lambing ease, lamb survival, ewe behaviour as mother and the early growth of the lambs.

The purpose of this Master?s thesis is to examine the information needs of reporters at a Swedish daily newspaper, and see if they are met by the information resources provided by the newspaper. It examines if there are resources which are not used and why. The examination is based on Henczel?s model for information auditing.

During the later part of the 20th century the amount of children and adolescents in Sweden who reported psychosomatic illness have greatly increased. The main reason is estimated to relate to weak resources in school and school healthcare. Increased resources do not always have to encompass investments for school and school healthcare. Other resources play an important part as well. A child?s domestic situation serves as one of those resources where fundamental knowledge and values are set.

An array of different retinal disorders is present as a threat in quite a number of dog breeds. These often lead to profound visual impairment or blindness. Many of the disorders are genetic, and they are, in Sweden as well as in other countries, subject to breeding programmes. The anatomy of the eye and the retina, as well as current examination techniques (ophthalmoscopy, electroretinography (ERG) and genetic analysis) are described. The more common retinal disorders encountered in dogs in Sweden are discussed: retinal dysplasia, generalized progressive retinal dystrophy, retinal pigment epithelial dystrophy, collie eye anomaly, sudden acquired retinal degeneration, retinal detachment and choroiditis. The possibly affected breeds are listed. The value of diagnostic findings is discussed and current advances on the subject in ophthalmologic research are accounted for..

The aim of this essay has been to increase the knowledge of which resources there are in compulsory school, their function and how they are experienced by teachers and students. By individual interviews I have examined teachers experiences of their work with students in need of support in core subjects. I have also examined how students experiences the help that they get and if they want to change anything. In my essay I have concentrated in a few main questions, such as; which resources compulsory school uses, teachers work with students in needs of support in core subjects, the extension of students needs, how students experience the help that they get, how they feel about education in smaller groups and if there are any differences in needs, among students, connected to gender. Literature has earlier shown that there are too few resources in compulsory school and that students in need of support doesn?t get the help that they need.

This study aims to find coping resources in two different paradigms of pastoral care using coping theory from the psychology of religion. The intention is to find coping resources that are functional coping strategies to help priests and chaplains in their work with pastoral care. The research questions are: What coping resources can be found in the pastoral clinical paradigm and the contextual paradigm? What are the differences and similarities? The method used is template analysis style where the theories form a framework for the material used to analyse in this study. The theories used for this study are religious coping theory and pastoral care theory.

The main objective of this thesis is to examine the situation concerning information technology, computers and information resources for university students at a selection of universities, and their libraries, in Sweden. Another objective is to compare this situation to what is stated in policy documents on the subject, and if the size of the university matters regarding resources. The thesis starts with a discussion of several authors, Frank Webster, Paul F. Burton and Lars Qvortrup among others, and their views on the information society. These range from whether we are living in it, are in a transition period or are still in the Industrial Society.

This study examines the organization of the village society in Benestad, in southern Sweden, during the period from 1886 to 1928. The study focuses on the commonly owned resources in the village and how the landowners there came together and shared the resources. By studying the records of the societies? meetings, and in particular the cases that concerns the common resources, a categorization has been done. The results of the study show that the landowners in Benestad shared pasture lands, milk carriage and other resources with one another. Overall, the village society had a strong organization with at least two yearly meetings about the commonly owned resources.

ABSTRACT Epilepsy describes a neurologically caused condition which involves seizures. Epilepsy can be classified according to different types of causes and the nature of seizures can vary. Medication for epilepsy in dogs is limited in comparison with human medicine. Idiopathic epilepsy is the most common neurological disease and one of the most common genetic diseases in dogs. Because epilepsy has a higher prevalence in certain breeds, there is reason to suspect that it is a hereditary disease. The inheritance of idiopathic epilepsy is for most breeds not determined, except for a few variants of the disease.

AbstractThe genetic diversity in cultural plants is considered to be threatened due to global climate change and antropogenic influence. Unknowing of future conditions for cultivation, gene banks all over the world are now trying to build up costly safety nets of species and varieties that may become highly valuable owing to their specific traits and genetic heredity. Hence, in 2002 there was a national inventory, aimed at the Swedish public, asking for seeds believed to be lost. Among the resulting collected seeds were some accessions of garden bean, Phaseolus vulgaris. The objective of this particular study was to assemble a collection of unique varieties and discard possible duplicates.

The aim of this masters thesis is to study the reliability of the URL as the link between a bibliographic record and a web resource. The Swedish catalogue services LIBRIS and NetSök have been evaluated on three different occasions, to study how these services have succeeded in giving access to web resources by using URLs. Because URLs are changeable, we have tried to find out common characteristics of the URLs in broken links. To accomplish this study we have used a quantitative approach and evaluated five percent of the web resources in the catalogues using a random selection. We have also used documentation relevant for our study, among other things to illustrate previous studies of the nature of web resources and alternative solutions to URLs as access points to web resources.

The aim of this Master?s thesis is to investigate how a public library should sign and organize their resources to make them as accessible as possible to the users of the library. Our theory, Paul Arthur?s and Romedi Passini?s wayfinding theory, is about how people search through information loaded environments. Our empirical material consists mainly of three parts: an inventory of the resources and guiding at Hammarö bibliotek, eight interviews with visitors at Hammarö bibliotek and observations of how visitors use and interact with the library, its resources and guiding.

Genomic selection (GS) is used for selection of breeding animals of dairy cattle. GS is though not as extensively used within the beef industry. One reason for that is the low accuracy (rTI) of the breeding value that is of great importance for the final genetic gain. Causes to the low accuracy are high effective population size, a small reference population and a genetically differentiated population. There is however a market for genomic selection with High Density (HD) tests for beef cattle.

Suicide is the ultimate outcome of mental illness and is a big and serious problem in society. About 1500 persons commit every year suicide in Sweden and many more engage in suicidal behaviour. This review aims at, from research studies from the 21th century, find out the knowledge of riskfactors regarding the risk for committing suicide among adolescents. The research questions are: What does research say, from a psychobiological perspective, about riskfactors among adolescents regarding the risk for suicidal behaviour? How much does genetic factors have an effect on the risk for suicidal behaviour among adolescents? and : What is the importance of environmental factors such as family connections, friends and school environment concerning suicidal thoughts among adolescents?The method that is used in order to answer these questions is a researchreview including ten research-studies.