The female dog has a unique reproductive endocrinology, with high levels of progesterone throughout the 70-day long luteal phase. In this project, markers of glucose metabolism were studied and compared from the aspects of breed group and time in oestral cycle. The parameters studied were: glucose, insulin, progesterone, fructosamine and the newly introduced analysis of HbA1c. Hba1c was also further evaluated and discussed as a diagnostic tool in canine medicine.No differences in terms of glucose markers were found between a group of purebreed dogs of various breeds compared to a group of dogs with high risk of dioestrus diabetes, namely the Norwegian and Swedish elkhounds.No differences were found between the two sample occasions, anoestrus and dioestrus, concluding that there is no need for relating test results to the time of the oestrous cycle in middle-aged intact female dogs.There were statistically significant higher values of all glucose markers in diabetic dogs than in non-diabetic dogs. When it came to HbA1c, however, there was a larger overlap between the two groups, compared to fructosamine.

Ataxi är då hunden har svårt att koordinera sina rörelser och orsakas av att nervsystemet inte fungerar som det ska och degenereras. Degeneration av cerebellum och då specifikt purkinjecellerna och granulacellerna ger en form av ataxi kallat cerebellär ataxi. Denna typ av ataxi uppvisas genom att hunden (Canis lupus familiaris) står bredbent, har muskelkramper, obalanserad gång och ögonrullningar. Den genetiska bakgrunden till cerebellär ataxi hos hund finns beskriven hos flera raser, däribland beagle, finsk stövare, old english sheepdog, gordonsetter och coton de tuléar. Hos alla dessa raser nedärvs sjukdomen autosomalt recessivt och de orsakande mutationerna ger olika dysfunktioner inom nervcellerna som gör att de inte kan fungera som de ska och degenereras.

The female dog has a unique reproductive endocrinology, with high levels of progesterone throughout the 70-day long luteal phase. In this project, markers of glucose metabolism were studied and compared from the aspects of breed group and time in oestral cycle. The parameters studied were: glucose, insulin, progesterone, fructosamine and the newly introduced analysis of HbA1c. Hba1c was also further evaluated and discussed as a diagnostic tool in canine medicine.No differences in terms of glucose markers were found between a group of purebreed dogs of various breeds compared to a group of dogs with high risk of dioestrus diabetes, namely the Norwegian and Swedish elkhounds.No differences were found between the two sample occasions, anoestrus and dioestrus, concluding that there is no need for relating test results to the time of the oestrous cycle in middle-aged intact female dogs.There were statistically significant higher values of all glucose markers in diabetic dogs than in non-diabetic dogs. When it came to HbA1c, however, there was a larger overlap between the two groups, compared to fructosamine.

Med genteknik är det möjligt att ändra gensammansättningen i våra livsmedel och applikationen har väckt stort intresse, inte minst bland allmänheten. Genmodifierade (GM) livsmedel har varit föremål för diskussion sedan 1970-talet. Syftet med denna uppsats är att studera olika uppfattningar och representationer om genmodifierade livsmedel. Enligt teorin om sociala representationer har representationer dubbla funktioner. Den ena är att konventionalisera objekt och den andra innebär att representationerna intar en förutbestämd form.

A controlled recording in a studio is the basis of all voice treatment. However, this controlled way of recording voice patients' voices can be questioned. The voice use may be different in a natural environment. In children noise related voice problems are investigated in a study about voice and its development (BUG ? Child voice and noise).

Due to increasing regulations regarding new diesel vehicles particulate matteremissions the new Scania truck, Scania Euro 6, has been equipped with a particulatefilter. This component effectively stores the particles in the exhaust gas but must becleaned in order to prevent itself from clogging. The filter is cleaned through aprocess named regeneration which is a thermodynamic process in which thetemperature of the filter is raised through fuel supplied to the exhaust gas.The purpose of this thesis is to contribute to the development of improved controlstrategies of the temperature during the regeneration process through thedevelopment of model-based controllers. These controllers are designed in order tohave good performance in stationary as well as automatic regeneration.In order to develop these model-based controllers a model of the system isconstructed. The model is described as a linear thermodynamic grey-box model withflow varying parameters, showing good results in validation.The model provides a simulation environment during the controller design, which isfocused around the development of linear regulators with the exhaust gas mass flowas a scheduling variable whose size determines controllers? mode of operation.

A power system will inevitably be subjected to transient overvoltages, most often produced by switching operations and lightning strikes. These transient overvoltages may harm sensitive equipment without sufficient protection, but it is not an easy task to predict what transients may occur or how they affect the system. A fault occurred in a low voltage system at Forsmark 2012 and overvoltages from lightning were concluded as the probable cause. The three aims with this thesis are to develop and test a model of the power system at Forsmark 3, analyse the transient behaviour of the system when subjected to lightning surges and identify critical parameters, and lastly to provide a tool for investigating the protection of the system. The modelling and simulations were performed in the freely available simulation program LT Spice.

The female dog has a unique reproductive endocrinology, with high levels of progesterone throughout the 70-day long luteal phase. In this project, markers of glucose metabolism were studied and compared from the aspects of breed group and time in oestral cycle. The parameters studied were: glucose, insulin, progesterone, fructosamine and the newly introduced analysis of HbA1c. Hba1c was also further evaluated and discussed as a diagnostic tool in canine medicine.No differences in terms of glucose markers were found between a group of purebreed dogs of various breeds compared to a group of dogs with high risk of dioestrus diabetes, namely the Norwegian and Swedish elkhounds.No differences were found between the two sample occasions, anoestrus and dioestrus, concluding that there is no need for relating test results to the time of the oestrous cycle in middle-aged intact female dogs.There were statistically significant higher values of all glucose markers in diabetic dogs than in non-diabetic dogs. When it came to HbA1c, however, there was a larger overlap between the two groups, compared to fructosamine.

Multiple Congenital Ocular Anomalities (MCOA) is a genetic disease that affects primarily Silver coloured horses of breeds such as the Rocky and Kentucky mountain horses. In these breeds the Silver dapple colour is very popular leading to an increase of affected horses. The major feature of the disease is ocular cysts of variable size. Large cysts also lead to a variety of secondary syndromes, for example retinal detachment. In previous studies the locus for MCOA has been mapped to an interval of 420 kb on equine chromosome six.

This thesis examines the problems related to IT in the Swedish healthcare system, specifically the drug searching part of the electronic healthcare systems used in Sweden. The question formulation is divided into two questions: What parameters and functions are of greatest importance when performing a search on drugs, and how should these be presented in a graphical user interface? Thus the purpose is to answer these questions through developing a design concept, in the form of a prototype, which describes how a drug search can be carried out.The entry point is a central quality checked drug database that is managed and owned by Swedish county councils and regions. The problem is attacked through user-centered methods where interviews of physicians and developers, in conjunction with observations, are used to give an overview of the problem area as well as to specify a requirements specification for the prototype that this thesis aims to develop. The thesis result is a requirements specification in combination with a prototype that exemplifies how drug searching can be performed, the prototype is based the requirements gathered from the interviews with the user group of physicians..

The aim of the project was to investigate if Swedish rodents, brown rat (Rattus norvegicus), house mouse (Mus musculus), wood mouse (Apodemus spp) and water vole (Arvicola terrestris) captured in pig herds and in urban areas, constitute a reservoir for pathogenic Leptospira spp. Under Swedish conditions leptospirosis gives rise to reproductive disorders in pigs and symptoms of flu in humans. It has long been established that rodents are chronic carriers of pathogenic leptospires in their kidneys, and can spread the bacteria with urine. The old nomenclature of serovoars is still in use, but a new system of genetic classification has developed and today the genus Leptospira contains 17 species. There are several diagnostic test developed for leptospirosis.

Due to exploitation of the world?s rivers, the upstream migration of anadromous species is frequently delayed or even prevented. To mitigate these problems and allow fish to migrate past obstacles, structures such as fish ladders have been developed. However, recent studies show that many of the present fish passage facilities are deficient. Monitoring and evaluation of passage facilities is therefore crucial to enable necessary adjustments.

The Swedish Red Polled breed is threatened by extinction and there are only around 1100 animals left. The breed was popular in the early twentieth century, but since then the numbers have steadily decreased. The overall objective of this study was to find out whether there may be economic incentives for preserving the breed. The milk quality properties are of major importance in the production of dairy products. Therefore we would like to establish if the Swedish Red Polled breed carries favourable alleles at loci of relevance for milk quality, to potentially make the breed more interesting for milk production.

The aim of the study was to install a biogas system consisting of three tubular polyethylene biogas digesters at a rural household in Malawi and to evaluate the constructed biogas system with regards to relevant system parameters. The purpose was to evaluate if the technology is a possible solution to reduce deforestation and support Malawi in climate change mitigation and adaptation. The study was carried out in the southern part of Malawi in cooperation with the University of Malawi. Locally available materials were used to construct and install the system. Three different feed materials, cow, goat and a mix of cow and goat manure, were used in order to determine which one was best suited to utilise as a digester substrate. After the installation, measurements of temperature, pH, biogas production, biogas composition and system functionality were made. The results of the study show that a biogas system with tubular polyethylene biogas digesters can be successfully installed at a rural household and that the most suitable feed material is a mix of cow and goat manure.

The thick shelled river mussel (Unio crassus) has a fragmented distribution in southern Sweden. It is a threatened and protected species. In both the Swedish red list and the IUCN Red List of Threatened Species Unio crassus is classified as Endangered (EN). Causes for this classification are for instance differentiated bottom substrate and deterioration in water quality. In this study, habitat preferences of Unio crassus were investigated to assist in future restoration work.