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1103 Uppsatser om Genetic disease - Sida 47 av 74

Sexuella dysfunktioner hos kvinnliga patienter med multipel skleros. En litteraturstudie om sjuksköterskors delaktighet i sexuell information och rådgivning till kvinnor med multipel skleros

Sexual dysfunctions concerning women with multiple sclerosis (MS) are common. Since the disease preferably affects young individuals when establishment of family occurs, the result of these problems have a great impact on the individual and her family. The purpose of this literature review is to throw light upon these problems and respond the questions if the nurse may be the right person to give sexual counselling and in which way this may be done. The theoretical framework was Antonovsky´s concept "sense of coherence". The result is presented in four themes: bodily aspects, social aspects, information/counselling, and practical implications for nurses.

Sjuksköterskans omvårdnad av patienter med myelomatos och associerad kronisk smärta : en litteraturstudie

Background: Multiple myeloma is a malignant incurable cancer disease associated with severe chronic pain. The nurse has several important roles in the management of patients with multiple myeloma. This study focuses on nurse´s roles including the caring of pain relief.Aim: The aim of this study was to elucidate the nurse?s role in giving care to patients with multiple myeloma and associated chronic pain.Method: This literature study was based on scientific articles.Results: The nurse is in a key position to facilitate ongoing adequate pain and psychosocial assessment of patients with multiple myeloma. The study presents ways of relieving pain and suffering via different ways of caring management.

De anhörigas sjukdom : Anhörigas upplevelser av att vårda personer med Alzheimers sjukdom

 Bakgrund: I Sverige finns det cirka 160 000 personer som är drabbade av någon form av demenssjukdom och av dessa lider ca 60 % av Alzheimers sjukdom. Cirka en halv miljon svenskar beräknas vara anhöriga till någon som drabbats av Alzheimers sjukdom. Alzheimers kallas ibland för de anhörigas sjukdom, eftersom livssituationen förändras både för den drabbade och för de anhöriga. Syfte: Att beskriva anhörigas upplevelser av att vårda personer med Alzheimers sjukdom. Metod: Studien utfördes som en allmän litteraturstudie.

Miljöekonomiska analyser av smog och luftföroreningsproblemen i Kina

Rapid economic development and urbanization has led to an improved standard of living for the Chinese people. Meanwhile, a series of environmental problems have also appeared and smog, in particular, has caused the Chinese people to realize how serious the situation is. Smog has seriously affected normal economic activities and people's everyday lives, resulting in financial losses, increased mortality and disease. How to handle the smog becomes particularly important. The purpose of this study is to describe and discuss the underlying causes of two sources of pollution, particulate matter and sulfur dioxide, as well as what drives individuals' and firms' environmentally destructive behavior.

Kromatografi av polära läkemedel och metaboliter med HILIC-teknik

The purpose of this project was to investigate if retention of polar compounds that are given to treat tuberculosis, diabetes, inflammatory bowel disease and childhood leukemia could be obtained with HILIC separation. By varying different parameters for different types of columns the compounds were analyzed with the aim of finding guidelines for future method optimizations. To perform these analyzes three different columns were tested ? ZIC-HILIC (silica-based with zwitterions), ZIC-pHILIC (polymer-based with zwitterions) and XBridge Amide (amide functions). The results were evaluated with selected quality measures.

Grb10 and developmental programming: evaluation of a maternal diet restriction model during gestation

This study was conducted at the University of Bath, UK, from September to December 2014 as part of an ongoing research project aimed at elucidating how the Grb10 gene might act as a mediator of long-term health effects (such as predisposition to obesity, diabetes, coronary heart disease and hypertension) caused by environmental factors during development. This phenomenon is known as developmental programming. The purpose of this thesis was not primarily to answer any of the broader questions posed by this research project at large since this would require much more data than is reasonable to acquire over the course of a few months, but rather to evaluate the methods used in this project and reveal whether they are working the way they are presumed to. In the research project, which employs mice with the Grb10 gene knocked out as well as wild-type control mice, a dietary restriction model is utilized during gestation, which is supposed to generate offspring with lower birth weight and subsequent detrimental health effects in adulthood. This is supposed to be achieved by restricting the protein content of the pregnant mothers? diet to 9 % (as opposed to the control diet of 20 %) throughout gestation.

En jämförande studie mellan kreatininkoncentration i serum och GFR mätt med scintigrafi hos hund med misstänkt kronisk njursjukdom

Both serum creatinine and measuring GFR can be used to evaluate renal function in dogs suspected to have chronic kidney disease (CKD). Although high creatinine levels usually indicate renal disease, normal creatinine levels can be present in dogs with decreased renal filtration. Measuring GFR is generally believed to be the most accurate way of detecting decreased renal filtration and scintigraphy GFR using 99mTc-DTPA has been found to correlate well with the ?gold standard? inulin clearance method.When measuring GFR by scintigraphy, 99mTc-DTPA is injected intravenously and radioactive decay of technetium gives rise to gamma radiation, which is registered by a gamma camera. Pictures and curves of radioactivity in the kidneys are generated by means of a computer program.

Renal dysplasi hos hund :

Renal dysplasia is a developmental anomaly of the kidneys which is considered to be the primary lesion in juvenile progressive nephropathy, a condition leading to chronic renal failure in young dogs. It is defined as disorganised development of the renal parenchyma due to abnormal differentiation, and pathological lesions include persistent foetal structures, dysplastic tubules and cartilaginous and osseus metaplasia. The aetiology of renal dysplasia in dogs is still unknown, but possible causes are infection with canine herpesvirus, teratogenic substances or intrauterine ureteral obstruction. In some breeds renal dysplasia is a familial or inherited disease. Clinical signs of chronic renal failure, such as polyuria, polydipsia, vomiting, weight loss, anorexia, lethargy and anemia, usually appear before the age of 2 years.

Bayesiansk klassificering av ursprung för fångster av sill

Sammanfattning I september 2008 fångades 311 juveniler (unga individer) av arten sill (Clupea harengus) in vid fyra olika områden på den svenska västkusten; Råssö, Hunnebo, Askerö- och Gullmarfjorden. Genetiska, kemiska och morfologiska data (längd och vikt) samlades in i syfte att bestämma vilka populationer de härstammade ifrån. Fångster av sill är så gott som alltid av blandat ursprung eftersom individer bara samlas i de populationer de stammar ifrån vid den tid på året då det är dags för parning (lek). I den här uppsatsen klassificerar jag juvenilerna till tre regioner i vilka populationerna ingår, genom att jämföra de data som samlats in från juvenilerna med motsvarande data i en stor databas över populationer i Nordsjön, Skagerrak, Kattegat och Östersjön samt med ytterligare en population, Risør, som inte ingår i denna databas. Data om populationerna kommer från samples och de sanna populationsparametrarna (dvs.

Bortom Kultursponsring : En studie av samarbeten mellan teater och näringsliv

Bakgrund: Den svenska teaterscenen befinner sig i vad som tycks vara en ständig ekonomisk kris. De offentliga medlen räcker inte längre till, vilket har fått till följd att teaterinstitutionerna har blivit tvungna att söka sig nya inkomstkällor. Kultursponsring är en alternativ finansieringsform som har blivit allt vanligare. Vi vill undersöka kultursponsringens möjligheter för svensk teater. Syfte: Syftet med uppsatsen är att undersöka möjligheterna att gå bortom den traditionella definitionen av kultursponsring för att skapa ett helhetsperspektiv på utbyten mellan teater och näringsliv.

Ungdomars egen upplevda psykiska hälsa och skolsituation

The aim of this study was to describe non-surgical treatment options for the diseases mucositis and peri-implantitis found in present literature. The literature review also illustrates the effect of the treatment opptions on soft tissue with mucositis and peri-implantitis surrounding dental implants. The study reviews twelve scientific articles that have been processed from the aim of the study. The result shows six therapy options, Er:YAG laser, air abrasive, ultrasonic device, hand instruments, hand instruments in combination with antibiotics and hand instruments in combination with clorhexidin. The following methods are described according to how they are used and how they affect the soft tissue surrounding dental implants.

Sjukdomar i vallgräs : uppdatering av Faktablad om växtskydd -Sjukdomar i vallgräs (95 J)

In Sweden, 2011, ley was grown almost as much as cereals, which means that in terms of area, ley is an important crop. A lay can consist of either grass or grass combined with legumes e.g. clover. Forage grasses can be affected by many differ- ent diseases, some during the winter and some during the growing season. The diseases which do damage during the winter are called snow mold and can make large areas perish.

Assessing the ability of LARGE overexpression to prevent the development of muscular dystrophy

Duchenne Muscular Dystrophy (DMD) is a hereditary X-linked fatal disease that affects 1 in 3500 male births. It is the most common kind of muscular dystrophy in children and leads to death in the late teens or early 20s for many patients. The mdx mouse is a model of DMD that can be used to investigate experimental therapies. Overexpression of a glycosyltransferase, CT GalNAc, in mdx mice has been demonstrated to prevent the development of muscular dystrophy. Overexpression of another glycosyltransferase, LARGE, is currently being investigated as a treatment for another group of muscular dystrophies, the dystroglycanopathies. In this study, we overexpressed LARGE in mdx mice in order to investigate its effect on the development of muscular dystrophy.

Effekter av motiverande samtal vid prevention av hjärt- och kärlsjukdom

Hjärt- och kärlsjukdom är den främsta dödsorsaken i Sverige. Majoriteten av dem kan förebyggas med hjälp av en livsstilsförändring, men för att göra det krävs motivation. En evidensbaserad metod som används för att främja motivation och livsstilsförändringar är motiverande samtal (MI). Syftet med litteraturstudien var att utforska vilka effekter MI kunde ha i sjuksköterskans prevention av hjärt- och kärlsjukdom. Resultatet visade att MI hade en varierande, men genomgående positiv effekt i att förbättra de levnadsvanor som är kopplade till hjärt- och kärlsjukdom.

Genetisk bakgrund till ataxi hos hund

Ataxi är då hunden har svårt att koordinera sina rörelser och orsakas av att nervsystemet inte fungerar som det ska och degenereras. Degeneration av cerebellum och då specifikt purkinjecellerna och granulacellerna ger en form av ataxi kallat cerebellär ataxi. Denna typ av ataxi uppvisas genom att hunden (Canis lupus familiaris) står bredbent, har muskelkramper, obalanserad gång och ögonrullningar. Den genetiska bakgrunden till cerebellär ataxi hos hund finns beskriven hos flera raser, däribland beagle, finsk stövare, old english sheepdog, gordonsetter och coton de tuléar. Hos alla dessa raser nedärvs sjukdomen autosomalt recessivt och de orsakande mutationerna ger olika dysfunktioner inom nervcellerna som gör att de inte kan fungera som de ska och degenereras.

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