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1103 Uppsatser om Genetic disease - Sida 4 av 74

Hjärtsviktspatientens uppfattning om sin kunskap och den information de fått angående sin sjukdom och egenvård

Background: Heart failure is a complex condition which means that the hearts capacity topump blood is reduced. The aim of this study was to investigate how patients with heartfailure considered their knowledge and the information they received about their disease andself-care.Method: Patients suffering from heart failure, hospitalized at section 30 E (n=13), andpatients visiting the nurse led heart failure clinic (n=4) at Akademiska sjukhuset in Uppsala,were requested to participate in the study. The patients answered questions about knowledgeand information concerning self-care and their disease. Data were analyzed using SPSS 15.0.Results: The patients valued their knowledge about the disease as lower than their knowledgeabout self-care. The study showed that all the patients found the information they hadreceived about their self-care better than the information they had received about theirdisease.

Reproduktion och reproduktionsproblem hos taxtikar

Artificial insemination (AI) has had a great influence on the development of pig production and is today widely practiced (Gerrit et al., 2005). With AI, genetic progress can at a short period of time be spread worldwide compared with using natural service and the best boars can be intensively used. This is also one of the biggest risks with AI; the impact of semen containing a Genetic disease or contamination of pathogens can be enormous. Fortunately, it is a small risk of disease transmission due to many tests of the boars and the semen before use (Maes et al, 2008). It is important that the boars used for insemination have good breeding values along with good reproduction features and have good fertility results (Robinson et al., 2005).

Känsla av sammanhang i förhållande till ålder, egenupplevd sjukdomsbild och hälsotillstånd hos en grupp individer med reumatiska sjukdomar

Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.

Comparison of Different Electrophoretic Methods for Haptoglobin Phenotyping and an Investigation in Patients with Abdominal Aortic Aneurysm

Haptoglobin is an acute phase protein with important biological role because of its capacity to bind to haemoglobin. Haptoglobin exists in three major genetic polymorphism types: Hp1-1, Hp2-1 and Hp2-2, the distribution of which has been associated with abdominal aortic aneurysm (AAA), an asymptomatic aortic disease common among men older than 65 years.    Five different electrophoretic methods were tested according to their ability to separate the haptoglobin phenotypes. The detection was based on a produced hemolysate of blood in which haemoglobin binds to haptoglobin thereby forming a complex that can be detected by specific haemoglobin staining using TMB-dihydrochloride and hydro peroxide as substrate resulting in an azure-green color of the bands. Samples from 15 patients who had suffered surgery for not broken AAA, that is more than5.0 cmaortic diameter, and 15 samples from matched controls were analyzed.    Among the five tested electrophoretic methods best migration and separation was seen on the pre-cast agarosgel Hydragel HR on the instrument Hydrasys. The other four methods gave less successful results.

Review of the litterature and an attempt to evaluate intake levels of iodine and selenium in dogs with and without lymphocytic thyroiditis

The prime aim of this thesis was to investigate whether high or low iodine intake during certain periods of life was, or was not a strong risk factor for the development of canine lymphocytic thyroiditis (CLT). And secondly, if a high or low selenium intake in a combination with high or low iodine intake also may have an influence on that risk factor. To investigate this, a dietary questionnaire was sent out to dog owners. The dogs were selected from an ongoing genetic study of CLT. The questions investigated brand and type of feed during different life stages (puppy, junior and adult) and also if there were any use of dietary supplements.

Zoonotic respiratory infections and great ape conservation - an emerging challenge

The conservation of great apes faces many challenges, one of which is the threat of infectious disease outbreaks. Zoonotic transmission of respiratory diseases from humans to wild great apes has recently been confirmed. Since respiratory disease is one of the major causes of death in both gorillas and chimpanzees, this gives reason for major concern. Little is known about the risks of disease transmission from humans to great apes in natural environments, and there is a need for systematic risk evaluation. Researchers, conservation staff and tourists spend time in very close proximity of wild great apes, sometimes during long time periods, which poses a potential risk of disease spillover. However, the presence of researchers and tourists has been shown to decrease the risk of poaching, making the matter increasingly complex.

Framing och epidemier : En studie av framing i relation till fiktiva och reella epidemier

The present study aimed to replicate Tversky & Kahneman's' survey of 1981 The Asian Disease Problem. A survey was conducted on the Internet (N = 200). An identical problem was added, yet with The Swine Flu as the disease. This was done to be able to investigate if there are any order effects, and also if it matters whether the mentioned disease is fictional or real. The results show the same results as Tversky & Kahneman already noted; positively and negatively framed problems generate different responses from the participants.

Patienters uppfattning om den information och det stöd de fått och behöver för att hantera sin psoriasis

Background: One of the healthcare tasks is to inform and support patients. Information and support is very important for the management of the disease in patients with psoriasis. Healthcare often focuses on the medical aspects and can easily forget about the individual behind the disease.Aim: To explore what kind of information and support patients with psoriasis receive and need to manage their skin disease.Method: Quantitative study with descriptive design and qualitative elements by analysis of the questionnaire with open questions. The study included 22 participants.Findings: The majority of participants responded that they had received information about various therapies, medications and generally about psoriasis. The information participants most often responded they needed, was essentially continuous information and updates on treatments and knowledge about psoriasis according to medical science.

Child diabetes ? parents? experience Barndiabetes - föräldrars upplevelser

Background: Diabetes Mellitus Type 1 is increasing among children on large parts of the world. The disease strikes not only the child but affects the whole family. The parents are those who are responsible for the child?s treatment and well being. Purpose: The purpose of the literature review was to describe how parents to children with Diabetes Mellitus Type 1 experience and handle the situation around the child?s disease.

Felaktig alternativ splicing: Vissa mutationer i BRCA1, BRCA2, ER? och ER? är starkt förknippade med bröstcancer

Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause Genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly breast cancer and ovarian cancer.

Upplevelser av att vara vårdande närstående till en person med Alzheimers sjukdom : en studie av självbiografier 

Background:Alzheimer´s disease is a so-called degenerative dementia in which brain cells gradually degenerate and die. The disease causes memory disorders and the trait of character disappears. Alzheimer´s disease also affects the related parties that may take a great responsibility. Related caregivers are entitled to support from healthcare. Aim:The aim of the study was to describe the experiences of being related when caring for a person suffering from Alzheimer´s disease.

Att leva med kroniskt obstruktiv lungsjukdom :  Patienters beskrivning av sitt dagliga liv. 

Background;Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by airway obstruction. Common signs of COPD are the slow process and shortness of breath on exertion. The most important treatment is to quit smoking. Most nurses, regardless of where they work, will meet these patients, often when the patients are having respiratory disorders. Aim;the aim of this study was to illuminate how patients with COPD describe the daily life based on how he/she experience and cope with the disease.

Avelsarbete med mjölkproducerande getter ? fokus på Norge och Frankrike

The main part of the goats in the world is located in developing countries, whereas active breeding programs are mainly restricted to Northern America and Europe. Goat milk can be processed to several products and goat cheese is the main product. An organized breeding program is carried out in France and Norway but is not present in Sweden. Important selection traits for milk producing goats include milk, protein and fat yield along with protein and fat content. Functional traits have been more important the past years and they have large economic importance for the farmers.

En studie av projektet Datorn som pedagogiskt verktyg enligt modell 1?1 ur ett lärarperspektiv

In this essay I describe the development of my prose work entitled Jorden a?r platt (Earth is flat). In the text we encounter a woman whose 40-year-old brother is diagnosed with lung cancer. The brother has been living a hectic life of drug addiction. The relationship between brother and sister is characterized by ironic distance, but also a lot of love.

Kronisk hjärtsvikt hos katt

This student report is a literature study about cardiac insufficiency in cats and it is written mainly for veterinary nurses. It is about cats with an underlying heart disease that has led to an incompensated heart failure.It presents a general basis on normal anatomy and physiology, and also how to make the diagnosis, therapy and intensive care.The student report is also about the role of the veterinary nurse during the process of the disease, how to help the veterinarian in the best way, how to handle anesthesia in cats with a heart disease, which factors that can have a significant matter in feeding, and what advices to give to a pet owner with a cat with a incompensated heart failure..

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