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2243 Uppsatser om Ethical Assessment of Somatic Gene Therapy - Sida 49 av 150

Tidiga tecken på pankreasanastomosläckage efter kirurgi : en studie om hur dessa kan upptäckas med hjälp av ett bedömningsformulär

Bakgrund: Pankreatikoduodenektomi är den enda kurativa behandlingen av pankreascancer och pankreasanastomosläckage (PAL) är en mycket allvarlig postoperativ komplikation. Metoder för att identifiera detta i ett tidigt skede behöver förbättras. Den postoperativa övervakningen består till stor del av vitalparametrar men sjuksköterskan observerar även andra tecken på försämring. Metod: 32 patienter som genomgått pankreatikoduodenektomi inkluderades i studie. Ett bedömningsformulär innehållande 14 parametrar togs fram och användes för att identifiera vad i sjuksköterskans observationer som kan identifiera tidiga tecken på PAL.

Hur effektiv och säker är fingolimod vid behandling av multipel skleros jämfört med natalizumab?

Multipel skleros (MS) är en kronisk immunologisk sjukdom som slår på centrala nervsystemet (CNS) och kan leda till minskad neurologisk funktion. I Sverige finns 17 500 personer som fått en MS-diagnos. Den vanligaste åldern för insjuknande är 20-40 år och sjukdomen är dubbelt så vanlig bland kvinnor som bland män. Om patienterna inte får behandling finns risk för kraftiga funktionsnedsättningar. Syftet med detta arbete var att undersöka effekten och säkerheten med det perorala läkemedlet fingolimod jämfört med intravenös behandling med natalizumab vid MS.

Väsentlig anknytning : Betydelsen av bostad och väsentligt inflytande i näringsverksamhet för individens skattemässiga status

In Sweden a person is either unlimited or limited liable to tax. It is important to define this status since the consequence of being unlimited liable to tax according to chapter 3 § 8 Swedish income tax law (1999:1229) is imposed tax on every revenue from Sweden and overseas. When deciding the fiscal status Sweden uses the principle of domicile which makes the home of the taxable person important.Despite domilication in another country a person can be considered to have such bonds to Sweden that they still should be unlimited liable to tax here. During the development of the Swedish communal tax law (1928:370) the term essential linkage was introduced. There are numerous factors which can affect this assessment but in case-law some factors have been considered more important than others.

Genetiska defekter hos nötkreatur :

Genetic defects are caused by mutations in major genes where the gene?s protein product has a large impact on the physiology of the animal. The synthesis of the protein can be altered by a change in the nucleotide sequence, which can lead to malformation and in many cases death.One of the main reasons of increase in many genetic defects is the use of few bulls in breeding programmes, causing a reduction of the genetic variation. Genetic defects cause suffering for the animal and influences the production by, for example, increased costs due to misscarriages, lost milk production and expenditure for medical treatment. Bovine Leukocyte Adhesion Deficiency (BLAD) and Complex Vertebral Malformation (CVM) are two genetic defects that were widespread before the causative mutation was discovered.

Bibliotekariens kunskap: En textanalys av SOU 1969:37

The aim with this Masters thesis is to examine the professional knowledge of the librarian. The method used is text analysis of a state public investigation, SOU 1969:37, that concerns librarian education. The theoretical starting point is a theory of knowledge thats descended from Aristotle. Three different forms of knowledge are central concepts in the theory: the theoretical, the practical and the ethical. The main issue in this thesis is: In what ways did the investigators look at the librarians knowledge? Was it in a changeable period of time? In that case, what reasons could there be? The conclusion shows that educational political changes were affecting the whole educational sphere at the late 1960:s, and in the beginning of the 1970:s, including library education.

Immateriella tillgångar vid kreditgivningsbeslut : Assessment of intangible assets in credit decision

Samhället går mot en mer tjänsteinriktad och kunskapsintensiv produktion vilket har lett till att immateriella resurser har fått en större betydelse för företagens ekonomier. Några av resurserna uppfyller kriterierna för en tillgång och finns med i företagens balansräkningar. När företag är i behov av kapital ser bankerna till företagens balansräkningar för att göra en kreditbedömning. De måste då bedöma immateriella tillgångar.  - Hur bedömer kreditgivare företags immateriella tillgångar? - Vilken betydelse har denna bedömning för kreditgivningsbeslut? Syftet med studien är att beskriva hur kreditgivare bedömer immateriella tillgångar och vilken betydelse denna bedömning har för kreditgivningsbeslut.En kvalitativ studie har genomförts där datamaterialet har samlats in genomintervjuer med respondenter från tre olika banker. Två av de undersökta bankerna bedömer inget ekonomiskt värde på immateriella tillgångar men dessa är med och påverkar helhetsbedömningen av ett företag. Betydelsen av detta är att företag med för stor andel immateriella tillgångar får svårare att bli beviljade kredit och straffas med högre kostnader.

Tillämpning av GIS-analyser i MKB

The reason for performing an Environmental Impact Assessment (EIA) is to incorporate environmental concern in different kinds of plans and projects. The purpose of such an assessment is to identify and describe direct, indirect and cumulative environmental impacts.Geographical Information System (GIS) is a tool that can be used to combine spatial extension of both sensitive areas and different environmental impacts in a quick and easy way. Because of that, descriptions of environmental impacts and motivation of different standpoints on a specific issue can be more correct and easier to make if GIS is used as a tool.Hence, GIS can contribute to improve the quality of Environmental Impact Assessments. If the benefits of using GIS are to out weight the costs, geographical information of satisfactory detail, actuality and accuracy need to be available at reasonable prices.In this paper, case studies are carried out for three different geographical analyses to investigate the use of GIS as a tool in EIA. From these case studies, more general conclusions about the benefits and limitations of using GIS for Environmental Impact Assessments are also drawn.

Utveckling av ett frågeformulär för delaktighet : En pilotstudie

Background: The need for structured practice has in recent years appeared in connection with the request for a more evidence-based nursing. In psychiatric care with its complex disabilities, it is important to have methods to identify these. Research has demonstrated the importance of patient participation in nursing that has been shown to affect their mental health. It is essential to get to know how patients with mental illness are capable of involvement in their life situation. The ICF emerged as a useful theoretical framework for development of questionnaires of patient participation.Aim: The aim of the present pilotstudy was to develop and test a questionnaire for participation, based on ICF.

Small scale dairy farming in Zambia

Milk yield levels in dairy cows are influenced by many factors such as nutrition, breed, health status, management and environment. This study was conducted among small scale farmers in Zambia, where the climate can be dry for up to six months per year and cause a lack of green pasture for livestock and on-farm produced feed. The purpose of this study was to identify management factors that can influence milk yield at small scale dairy farms in Zambia, and present advice that could improve productivity, without the need of expensive investments. The study included semi-structured questionnaires presented to the farmers (n=29) including questions about cattle management and milk production. Testing of somatic cell count (SCC) with DCC (DeLaval Cell Counter) from herd milk samples (n=56) and observation of housing and animal body condition on-farm was also made.

Vad är ett gott samhälle? : En kvalitativ studie av gymnasieelevers uppfattningar kring vad som utgör ett gott samhälle, i förhållande till kursplanen i religionskunskap 1.

This essay is an analysis of how Swedish sixth form students interpret ?a good society?,an expression which is part of the main content of Religion1, the mandatory course inreligious studies. It is based on a a survey asking 198 students to define and reflect onwhat a good society might look like. A hermeneutic method has been used to analysetheir answers in relation to regulations and research.The conclusion is that although most students show themselves able to reflect on whata good society might be, their ability to use ethical theory and concepts required by thecourse?s grading criteria is limited.

Villa Furulid : gamla anor möter dagens behov

The last years? financial situation has contributed to an increased willingness from the banks to handle risks. The most important risk to cope with is a risk that is related to a customer?s ability to repay loans. Forecasts indicate that in the future, Swedish farmers will be facing profitability challenges, which points to a need to reconsider the banks procedures considering risk management in credit granting for agricultural businesses.Today?s risk management will be given two complements in this study.

Från disk till rum : Basel II-effekter på kreditrisk och information

This study examines the effects of credit risk and information disclosure in the new bank regulating system Basel II on bank and bank customer. The effects are then discussed in a perspective of the economic man and information asymmetric theories. Furthermore is the Basel II effects on the capital adequacy of Andelsbanken för Åland examined.The approach of the study is qualitative and several interviews with individuals on different levels of the examined bank, Andelsbanken för Åland, have been carried out during the collecting of empirical facts about the effects of the regulating change from the Basel I system to Basel II.The research findings are as follows:Andelsbanken för Åland have increased its capital adequacy ratio from 12,7 percent to 14,4 percent, mostly due to lower risk weights on housing mortgages compared to Basel I. Andelsbanken för Åland have started to use a completely new credit risk and customer assessment system which classifies every customer and gives them a credit rating. The system cause a much heavier information gathering of the customers profile as well as a much better assessment of risk than the previous system, which the bank finds positive.

Läsutveckling : En studie av elever i år 4

Syftet med vår studie var att undersöka, analysera och diskutera lärarens, elevers och föräldrars medvetenhet och engagemang om elevernas progression inom läsinlärningen. Analys och slutsatser byggde vi på våra resultat och modern forskning om barns språkinlärning. Detta gjorde vi med hjälp av en klass bestående av 1 lärare, 19 elever och deras föräldrar. Vi använde oss av kartläggningsmetoderna God Läsutveckling och Ordkedjor, enkäter och intervju. Resultatet av vår studie visade att kartläggningsmetoden var betydelsefull, men metodvalet inte var det avgörande för läsutvecklingen hos eleverna.

Att som missbrukare inte vilja leva mer - om samband mellan missbruk av alkohol och droger och suicidala handlingar

The purpose of this study was to explore the connection between substance abuse and completed/attempted suicide. Central questions were who the substance abusers who commit suicidal actions were. The study also tries to find out which factors that contributes to this behaviour and why it is so common amongst substance abusers. All from the point of view of three scientist and three persons working with treatment of addicts who were interviewed. The results of these interviews were analysed on an individual level with a psychological theory.

"... så här är det bara" : Adoptivföräldrars tankar och känslor om barnets bakgrund

Adoptive parents need to be able to reflect on the interaction with the child, both from the perspective of their own relational experience with the child and from the perspective of the previous experience of the child. This essay explores five adoptive parent´s thoughts and feelings about their children?s background. It also looks into how they think that the children?s background influences their way of expressing their needs and how this makes the parents feel.

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