The process of drug discovery is very slow and expensive. There is a need for reliable in silico methods; however the performance of these methods differs.This work presents a targeted study on how the drug discovery methods used in OpenEye?s tools ROCS, EON and FRED perform on targets with small ligands. It was examined if 12 compounds (markers) somewhat similar to AMP could be detected by ROCS in a random data set comprised of 1000 compounds. It was also examined if EON could find any electrostatic similarities between the queries and the markers.

The report describes the thesis I, Philip Bergstrom, have done at the University of Gotland. The work comprises 15 credits and is at bachelor level and has been done in collaboration with Lyktan Bankeryd Belysning.The project consists of developing the design of a kitchen lamp for the Swedish home following the catchwords stripped French bistro that will fit into the Lyktan Bankeryd lighting spring collection 2013, and it should not look too alike any existing lamp on the market today.The work includes analysis of the company's current products and the image the company wants to project, analysis of three other companies' products to draw inspiration from, and a simple ergonomic study of the lights in the kitchen.The final result achieves the demands made and fits well in the intended environment, there is also the possibility for further development of both a floor lamp and a wall lamp..

This report deals with an exam report written by Olle Hjalmarsson and Thomas Likar, students at Högskolan i Halmstad. The project was carried out for Haldex Traction AB in Landskrona whose business consist of manufacturing automatic all wheel drive systems (AWD-system). These systems consist of a plate clutch which activates all four wheels of a 4-wheel driven vehicle. An important component in these clutches is the accumulator which basically consists of a piston under the load of a spring which creates an oil pressure with the help of an electric motor used for actuating the clutch.At Haldex difficulties has been experienced regarding the assembly of the accumulator parts due to the small tolerances between the piston and the hole of the accumulator in the cast aluminium housing. Attempts have been made to assemble the parts in existing robot cells.

In this report a study is carried out with the aim to identify added values of EPC projects implemented in schools in order to increase the interest of EPC projects on the market. The report examines how the planned maintenance, supervision, maintenance and corrective maintenance is affected, how insurance premiums and terms are affected, the indoor environment and how the tasks of the operating staff is changing. A literature study of energy savings, energy use in schools, maintenance and insurance as well as how energy efficiency improvements are related to the Swedish environmental objectives has been made. Visits were carried out in Ludvika, interviews were also carried out with operation technicians and local strategists in Ludvika as well as employees of insurance companies.Schools often have neglected maintenance and problems with ventilation and indoor environment. Schools also have a large energy saving potential due to their low utilization, mainly because they are empty parts of the year.

The purpose with this project was to invent a product that secures buildings sewersystems against rats. The problem was presented to us by a local building maintainer inHalmstad, who had experienced big problems with rats in his real estate. The project hasbeen carried out by Per Johansson, Robert Lidén and Niclas Nilsson under our ownauspices. We are primarily sponsored by AMLI Business Partner but also byInnvationsgruppen, Halmstad Fastighets AB and Anticimex.To be able to secure a whole building with only one product we came to the conclusionthat the product must be placed in the horizontal sewer pipe that connects with themunicipal sewer system. Our goal was to invent a product that prevent rats from passingand at the same time not affect the water flow.

The earmould acoustics affect the amplification that the hearing aid is programmed to give to its user. It is therefore important that the choices made for the earmould are correctly done. One choice is regarding the shape of the soundbore that affects the frequency response of the hearing aid above a certain cut-off frequency. The purpose of this project was to measure the frequency response when altering the shape of the soundbore in the earmould. Additionally, the aim was to examine how the frequency response is affected when the shape of the soundbore is not set or is not possible to set in the software when programming the hearing aid.

In most software engineering project, users are only involved in the beginning of the project as a help to design the requirements specification but users can be involved after this phase too, but is it effective to do so? With this report we would like to investigate how effective it is to involve users after the requirements specification has been written and approved. To find out how effective it is to involve the users we try some fast and simple involvement techniques on a quite far gone project. These techniques include ethnographic studies, prototypes and surveys. We also interviewed a couple of people who work with usability and finally delivered a report with our results to them to find out if they found our result relevant. By also documenting how much time we spent involving users we will show to which degree user involvement is effective. We found out that a couple of fast techniques could get very much result in the form of usability enhancing suggestions to the developers.

This report describes a project, which was carried out as a final thesis covering 30 ECTS during the final semester of the Master of Science programme Industrial Design. The assignment was issued by Fagerhults Belysning AB in Habo. The assignment was to design a family of products in which LED was to be used as a source of light. The main focus in the initial part of the project was to find a way to design the inside of armature which was suitable for LED technology. An armature, already in the range of products at Fagerhult, with the desired qualities that was to be strived after was the Zintra. The lighting source of the Zintra is a compact fluorescent lamp.

The aim with this thesis is to examine how childrens librarians apprehend and use the nationally initiated reading project Bokjuryn as an instrument in their work. The main question is as follows: How does Bokjuryn work related to the way public libraries pass on literature? Two questions are asked: How does the childrens librarians use Bokjuryn as an instrument and how do they motivate their work with it? and How do the childrens librarians view the reading project Bokjuryn as a method of passing on literature? The study is based on qualitative interviews with five childrens librarians. As a theoretical starting-point Jofrid Karner Smidt´s work about mediation of literature has been used. A model has been created and used based on Louise Limbergs analyses of the differences between school libraries and public libraries to analyse the result of the interviews together with other literature.

A consultant is an external expert that exists within all types of organizations. The consulting service can be divided into individual practitioners and large companies whose sole task is to hire out consultants to clients. The need for consultants has grown due to the restructuring of Swedish businesses during the past decades. They have put parts of their business on contract. This has led to a market with other player that have been able to focus on these parts.

AbstractThis report describes our ten week long thesis work which is the last task in our education in mechanical engineering at Linköpings University. The project has been performed at Siemens Industrial Turbomachinery AB?s service department. The company which is located in Finspång produces, sells and provides service for steam and gas turbines around the world.The purpose of this project is to help Siemens develop their maintenance programs for two of the auxiliary systems which are a part of the complete steam turbine system. These are lube and control oil systems.The project is restricted to two of Siemens maintenance products, No Stop Check (NSC) and the annual Safety Inspection (SI).

I många sammanhang är det önskvärt att importera data från textfiler, excelfiler och liknande till en databas. För detta krävs att data i något skede översätts till en ER-modell (Entity Relationship), en modell som beskriver relevanta delar i ett databasschema. Modellen för hur denna översättning ser ut varierar från fall till fall.I det här examensarbetet har en applikation tagits fram för import av data till en ER-modell ur ett modellperspektiv i linje med Model Driven Architecture (MDA) ?. Vinsten ligger i att använda en metamodell som beskriver hur olika modeller för transformering från tabelldata till en ER-modell får se ut.

Lansen Technology develops and sells alarm systems. The communication between the system devices are wireless. The radio protocol used by the system is developed by Lansen with the purpose to be energy efficient. The alarm systems target groups are individuals, businesses and government agencies. The current system is installed, configured and controlled from a control panel for all audiences.

Background Research concerning footing and its contribution to injuries has been conducted primarily in racing Thoroughbreds. Studies in UK and Japan indicate that some specific factors could be responsible for an increase in performance-associated injuries. Researchers in Sweden have performed studies on Standardbred trotters. More research is needed to be done on equestrian sports since requirements on footing are not exactly the same in riding and trotting horses. The lack of scientific evidence on the construction of equestrian surfaces has lead to anecdotal validation of designs.

The following study is a discourse analysis of the concept of critical thinking within pre-school teacher education. It considers the following questions: how does the concept of critical thinking appear in policy documents, central to the pre-school teacher education, and which possible conceptions of critical thinking are conveyed by students and teachers active within the education. Additionally, the study seeks to discuss, as well as suggest a possible relation, between the findings of those two questions. In reviewing the material (consisting of five semi-structured interviews with students and teachers, and of a selection of policy documents central to the education), I argue the existence of a sort of project within the education, which presents critical thinking as a higher value. At the same time, I argue that the concept is not defined or concretized. This project, however, as I suggest while drawing upon Foucault?s ideas of discourse and government, involves a rather high degree of control.