Escherichia (E) coli is one of the most common udder pathogens associated with acute clinical mastitis in Swedish dairy cows. The aim of this study is to review some of the existing literature on E coli mastitis from a Swedish perspective. The bacteria, its most important characteristics, and diagnostics under field conditions is covered, as well as what happens during infection, how E coli affects the cow and which consequences this have. Clinical symptoms associated with E coli mastitis are described and information on when these cases of mastitis usually occurs is given. Risk factors in the cow?s enviroment are described as well as the importance of the cow?s immune defence.

The purpose of this study was to evaluate Komm-A, a model for usingcommunication books in clinical practice for people with aphasia. The studyconsisted of two group studies and one case study. One of the group studies had apretest-posttest design and consisted of nine couples; a person with aphasia andhis/her communication partner. The material used was Quality of communicationlife scale (QCL), Communicative effectiveness index (CETI), Goal attainmentscaling (GAS), and a questionnaire to the communication partner. The other groupstudy consisted of seven speech-language pathologists who worked with thecouples according to the Komm-A model.

VEP, visual evoked potential is an electrophysiologic test that can be used for evaluating the higher visual pathways. The aim of this study was to investigate if it is possible to adapt this method to horses. This method could have a clinical use in addition to the existing diagnostic methods that are available to evaluate vision in horses. Firstly, this study contains a summary of relevant studies done on animals and, secondly, an experimental part where the possibility of recording VEP in nonsedated and sedated horses is investigated and where to position the recording electrode to obtain the best results. Our results show that it is possible to record VEP in horses in a clinical setting. VEP was best recorded in the sedated horse to avoid movement artifacts and other disturbances.

Hypoadrenocorticism (Addison´s disease) results from insufficient production of glucocorticoid and mineralcorticoid hormones from the adrenal glands. The disease is often difficult to diagnose in an early stage because of the multitude of associated vague clinical signs. The standard poodle is one breed presupposed to be at higher risk of developing the disease. The purpose of this study was to give a review of canine hypoadrenocorticism as described in literature, and to characterise Addison´s disease in a population of standard poodles in Sweden. Statistics on incidenceproportions by breed for hypoadrenocorticism from the database of the Swedish insurance company Agria are presented.

The aim of the present study was to investigate the effect of strategy for grouping calves into group pens with automatic milk-feeding systems on the calves' health and growth rate. The usefulness of changes in feeding behavior recorded by the computerized milk-feeder during periods of illness to identify calves with clinical diease was also studied. In the first experiment, 64 calves were moved in and out of group pens in a continuous way, while 46 calves were transferred into group pens until the the pen was considered "full". The calves in the latter groups were then held together until weaning. It was found that calves in the fixed groups grew approximately 100 g / day more compared to the calves in the dynamic groups. Signs of clinical respiratory disease were less frequent in this group, while the incidence of diarrhoea was slightly higher. In the second experiment health parameters, milk consumption and feeding behaviour was recorded daily for 46 calves.

Clinical signs of hypocalcaemia in dairy cows are easily recognized, and a rapid response to treatment generally confirms the diagnosis in the field. However, clinical signs of other disorders in cows, such as toxemia, calving paralysis, or muscoskeletal injury, may mimic those associated with hypocalcaemia. Therefore, making a diagnosis of hypocalcaemia on the basis of clinical signs alone may be difficult. In ambulatory veterinary practices, cow-side tests are useful to make the diagnosis and prognosis easier. Kruuse?s Kalcium Test is a cow-side test based on the principle that calcium ions are necessary for coagulation of blood, and that chelation with EDTA prevent coagulation.

Joint-related diseases including hip dysplasia (HD) and elbow arthritis (ED) can in advance cases lead to that the dog has to be put down, and these diseases are also the cause to expensive veterinary treatments of many large breeds, including Labrador Retrievers. The aim of this study was to make a follow-up study on the 271 Labradors, who previously participated in a study on the effect of nutrition and exercise on hip and elbow status in a birth cohort born year 2000. That study investigated the relationship between nutrition, exercise, and HD and ED. A follow up study on the same dogs at 5-6 years of age investigated the clinical effects of the radiological hip and elbow status at 1 years of age and if was effected by body condition score. This study took place in 2011-2012 and 187 Labrador retrievers participated.

This study was performed to investigate the possibility to use ultrasonography as a diagnostic tool for sub-clinical mastitis in dairy cows. Five cows with high cell counts, and four cows with low cell counts were selected as cases and controls, respectively, and their udders examined with ultrasound during a 5 week period. The image of the udders of cows with high cell counts exhibited small, hyper-echoic, rounded foci, approximately 1 cm in diameter, near the milk cisterns and the base of the teats. These changes were not found consistently in all cows with high cell count, however. Ultrasonography may be a valuable complementary tool in the diagnosis of sub-clinical mastitis in dairy cow, but more cases need to be monitored before its full value can be ascertained..

sjuksköterska (I. Dahl).

The aims of the practical work carried out for this thesis were to redesign a clinical decision support system for thoracic surgeons, called AssistMe, and to evaluate the concept behind this system. The main objective of the thesis is to give an account of the considerations that were found to be of key importance for designing a clinical decision support system for thoracic surgery. Another aim was to let future users test the system after it had been redesigned and evaluate the concept behind it. The thesis also investigates users? experience of the system and their views on whether it would be applicable in their daily work practice.

Information is essential in order for pharmaceutical companies to be successful. This essay focuses on the information provision of pre-clinical scientists at AstraZeneca R&D Lund, and the role of the company library in this process. In semi-structured interviews, four pre-clinical scientists were asked to describe their information provision regarding what type of information they need, how they find it and what sources of information they use. Four librarians from the company library were also interviewed to give their perspective on the information provision of pre-clinical scientist. The study also aimed at comparing the image of the process as described by the scientists themselves and the librarians.

Establishing a reference interval for plasma fibrinogen in foals Fibrinogen concentrations were analysed in EDTA preserved blood plasma samples from 34 thoroughbred foals born in 2001 and 2002 at one stud farm. The foals were between 0 and 240 days old at the time of the sampling, and there were 19 fillies and 12 stallions in the group. The foals were examined for clinical symptoms of disease and their body temperature was measured before blood was sampled from the jugular vein. From totally 156 blood samples, 31 were selected as originating from clinically healthy foals, and used to determine a reference range for thoroughbred foals. Samples originating from foals showing clinical symptoms of disease or an abnormal body temperature at the time of sampling, were classified as coming from unhealthy animals.

Background: Osteoarthritis is understood to be a common cause of pain and dysfunction in cats; however there are few validated pain assessment methods for chronic pain in cats. In order to design a proper pain questionnaire, it usability need to be tested in both sound and sick cats. Aim: The aim was to investigate the usability of the pain questionnaire ?Lifestyle changes in cats? by compiling the results from the pain questionnaire reflecting the lifestyle in 30 healthy cats and compare it to the results from a clinical examination, as well as proposing improvements and additions to the questionnaire based on a literature review. Material and method: 30 healthy cats participated in the pilot study; the pet owner filled out a pain questionnaire with 16 questions regarding their cat´s behavioral and eventual changes in behavior and physical function. Thereafter the cat walked over a pressure measurement mat and finally underwent an orthopedic-directed clinical examination. The literature was found on Web of Knowledge, PubMed, Sciencedirect, and Google Scholar and also with the help of my supervisors.

The main purpose of this study was to translate Stuttering Severity Instrument 3 and to evaluate its reliability and validity. Five speech-language pathologists assessed 35 adults who stutter with this assessment tool. Overall the results showed a very high inter- and intrarater reliability. A highly significant correlation between Stuttering Severity Instrument 3 and ratings of severity, made by the speech-language pathologists, strengthen the validityof Stuttering Severity Instrument 3. No correlation was found between the total score of Stuttering Severity Instrument 3 and the self-report measure Overall Assessment of the Speaker's Experience of Stuttering, whichindicates a lack of social validity in Stuttering Severity Instrument 3.

Syftet med uppsatsen var att undersöka och beskriva hur man arbeta med mentalisering/ reflektiv funktion i olika familjeterapeutiska metoder. Uppsatsen bygger på intervjuer med sex erfarna familjeterapeuter med olika inriktning som besvarar generella frågeställningar samt beskriver hur de skulle arbeta med ett kliniskt exempel.Resultatet visar att familjeterapeuterna, oavsett tidigare kännedom om begreppen tänker likartat kring mentalisering och reflektiv funktion i sitt kliniska arbete, och att alla utom en terapeut väljer snarlika förhållningssätt i arbetet med det kliniska exemplet. Slutsatsen är att mentalisering/reflektiv funktion är något som familjeterapeuterna ser som vägen till att skapa förändring och att familjeterapeutiska metoder kan användas för att arbeta med och förstärka mentalisering och reflektiv funktion.The purpose with this essay was to examine and describe how to work mentalizing and enhancing the reflective function with various family-therapeutic methods. The essay consists of interviews with six experienced family therapists with various orientations who answers general questions and describes how they would work with a clinical example.The essay concludes that the family therapists, regardless of previous knowledge of these concepts, think alike about mentalizing and reflective function in their clinical work. All except one also choose a similar approach in their work with the clinical example.