There are about 700 000 dogs in Sweden. Roughly 70 % of the dogs are purebred and registered in the database at the Swedish Kennel Club (SKC). The database includes records of birth date, pedigree, offspring and results from e.g. veterinary examinations related to genetic health programs.Every year approximately 10% of the dogs die; most are euthanized by a veterinarian. Dog mortality data is stored as digital medical records at animal clinics and in insurance databases.Dog owners tend to register their puppy in the SKC, but they rarely report that the dog has passed away.

This student report is about canine infectious skin diseases. It is primarily directed at veterinary assistans. The report includes a description of the skin?s structure and immunologic defences. The four types of allergic reactions are described. Different diagnostic techniques are also accounted for. The skin diseases included in the report are: fleas, lice, Sarcoptes scabiei, ringworm, Cheyletiella and leishmaniosis.

India is the country with the highest prevalence of rabies in the world, with about 20?000 human deaths occurring every year. The country also has a heavy burden of free roaming dogs, mainly because of the high amount of edible waste in the streets, which are the main hosts for the disease. Therefore to truly extinguish rabies, the main focus should be on the dogs, both stray dogs and owned. One method is to vaccinate all dogs against rabies.

Hästinfluensa, orsakat av ekvint influensavirus (EIV) förekommer över hela världen och är en vanlig respiratorisk sjukdom hos häst. Nyligen upptäcktes att EIV passerat djurslagsbarriären och orsakat sjukdom hos hund, vilket har lett till utvecklingen av canine influensavirus (CIV). Detta har sannolikt skett via direkt överföring utan föregående mutation av viruset. Flera faktorer spelar in i processen men den viktigaste tycks vara att häst och hund uttrycker samma typ av ytreceptorer i luftvägsepitelet (SA?2,3Gal), vilket möjliggör för EIV att binda in till och infektera cellerna hos både häst och hund.

Kennelhosta är ett samlingsnamn för en grupp virus- och bakterieinfektioner som ofta drabbar hundar som är tillsammans med större grupper av andra hundar. Symptomen är oftast milda, vanligtvis med en torr, hackande hosta, men kan i vissa fall ta sig uttryck som svårare symptom som lunginflammation. De vanligaste infektionsämnena är hundens parainfluensavirus (CPIV), hundens respiratoriska coronavirus (CRCoV), hundens adenovirus typ 2 (CAV-2) och bakterien Bordetella bronchiseptica. Hundens respiratoriska coronavirus är det virus som undersöktes i studien som ligger till grund för den här rapporten. Familjen coronavirus innehåller de största membranomslutna virusen med RNA som arvsmassa med genomstorlekar på upp till 32000 baser.

In couples diagnosed with unexplained infertility, the woman has normal ovulatory cycles and no organic pathology, and the man has normal semen. The period during which the implantation of an embryo can occur is defined as the window of implantation (WOI). For infertile women, disturbances in the endometrium maturation are hypothesized to impair the uterine receptivity for embryo implantaition. However, there are still no methods found to predict endometrial receptivity.Hemoglobin related-proteins hypothesized to be involved in embryo implantation have been found in the endometrium in both fertile and infertile women. The aim of this study was to determine whether there were differences in the expression of hemoglobin-related proteins, hemoglobin-?, cytoglobin, fetal hemoglobin and haptoglobin in the endometrium of fertile and infertile women.

The aim of this study was to determine a method to habituate treadmill-naive Labrador Retrievers to walk and trot on a treadmill. 17 Labradors was equipped with reflective markers glued to the skin. Their motions were captured with six 240 Hz infra-red cameras as they walked and trotted on a treadmill three times a day for two days. Also the heart-rate was recorded. We then used QTM and custom built software to analyze the measurements.

Preservation of cells and tissues by freezing at temperatures below 70°C has led to new possibilities for the storage of germ cells for fertility preservation. During the freezing process problems might occur, the greatest being ice crystallization which can cause membrane destruction and thus cell death. To minimize this risk, solutions that reduce the freezing point can be added to reduce crystallization and increase survival rates. These solutions are called cryoprotectants. The best method for freezing is still not known.The aim of this study was to analyze the effect of various parameters on the survival rate of human semen frozen with liquid nitrogen.

Idiopathic pulmonary fibrosis (IPF) is a chronic respiratory disease with an estimated incidence of 3-6 cases per 100 000 inhabitants in Sweden. There is no cure for the disease, which inevitably leads to death. A similar disease has been found among terrier dogs, with an especially high prevalence in the West Highland White Terrier (WHWT). Dogs with pulmonary fibrosis become lethargic with exercise intolerance, and in some cases they develop cough and respiratory distress. This thesis gives a brief review of the field of pulmonary fibrosis and presents a method for analyzing surfactant proteins in bronchoalveolar lavage (BAL) in the dog.

The Annexin-V/propidium iodide (AV/PI) assay detects early membrane changes in spermatozoa and viability using flow cytometry. It is an objective method that evaluates a much larger number of single spermatozoa compared with the usual estimation of motility, the most commonly used method for routine sperm evaluation. In the present study four ejaculates from four stallions were used in a split-sample design to investigate whether and how the number of intact spermatozoa is affected over time and after incubation at different temperatures, either those recorded during shipment of stallion semen for AI (9 or 5°C) or room temperature (20°C). The Annexin-V results did not reflect the motility results that were monitored in parallel. While motility decreased over time, the number of spermatozoa with intact membranes (viable) remained unchanged for at least 21 hours following a short period of initial instability.

The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

Pigs in Swedish organic production systems have been shown to have more findings of arthritis at slaughter, compared to pigs in conventional pig production. With this in mind a study was performed, to primary, investigate variation in exterior, gait and weight gain between sire breeds and, secondly, to investigate variation between herds, season, gender, age and assessment occasion on these recordings. Swedish commercial hybrids, crosses between Norwegian Landrace and Swedish Yorkshire were inseminated with either Hampshire or Duroc as terminal sire. All the pigs had known pedigree as each semen dose contained sperms from one individual boar. All piglets were individually tagged closely after birth, and exterior and gait assessment were performed at two separate occasions, early and late during the fattening period.

Inbreeding has become a problem in some horse breeds. Studies show that it may lead to inbreeding depression which affects e.g. reproduction traits. In the wild there are mechanisms that make horses avoid mating with close relatives. When selection is done by humans this mechanism is removed and intensive breeding for a few traits, for example good racing results, can become a problem.

I denna studie har förekomst av progesteronreceptorer i olika typer av primära juvertumörer undersökts med hjälp av immunohistokemi. Dessutom har tumörceller från carcinomcellinjen CMT-U27 odlats i olika cellodlingsmedium och exponerats för olika testsubstanser som binder till progesteronreceptorn (progesteron och RU486/mifepristone). Cellernas receptoruttryck och progesteroninnehåll utvärderades med hjälp av ELISA och tumörcellernas viabilitet analyserades med Colorimetric Cell Viability Test. Av resultaten framgår att samtliga undersökta primära juvertumörer uttryckte progesteronreceptorer. De odlade cellerna hade högre cellviabilitet när de odlades utan fetalt bovint serum (FBS). Efter exponering med progesteron minskade tumörcellernas uttryck av progesteronreceptorer, vilket hämmades av mifepristone.

VikingGenetics is one of the world's largest breeding companies. 2008 was launched two new products, X-Vik and GenVik. Now VikingGenetics want to get information about the effects of the marketing. We have investigated the differences in knowledge and use of the products between different livestock associations, size of herd and farmers' breeding interests. The method used was by sending out a questionnaire by mail.