The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

Measurement of plasma concentrations of natriuretic peptides have been suggested to be of diagnostic and prognostic value in canine cardiac disease. In several previous canine studies, however, a considerable overlap between investigated groups has been identified. A reliable natriuretic peptide test for use in clinical practice requires establishment of reference values for natriuretic peptides in healthy dogs and cut-off values for subclinical disease as well as for clinical signs of congestive heart failure. Numerous physiological, pathological and pharmacological factors, aside heart function, may influence concentration of natriuretic peptides. A potential effect of dog breed on natriuretic peptide concentration has been suggested but has, to our knowledge, not previously been specifically studied.

There are about 700 000 dogs in Sweden. Roughly 70 % of the dogs are purebred and registered in the database at the Swedish Kennel Club (SKC). The database includes records of birth date, pedigree, offspring and results from e.g. veterinary examinations related to genetic health programs.Every year approximately 10% of the dogs die; most are euthanized by a veterinarian. Dog mortality data is stored as digital medical records at animal clinics and in insurance databases.Dog owners tend to register their puppy in the SKC, but they rarely report that the dog has passed away.

The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

This student report is about canine atopic dermatitis It includes a description of the immunologic mechanisms and how the reaction affects the body. The symptoms are various, most common is pruritus, erythema and alopecia and directly associated with the immunologic reaction. The diagnostic process includes symptoms, physical findings, differential diagnosis, intradermal test and serological test. The options of treatment are several and vary for each patient. The report includes hyposensitization, medical treatment such as corticosteroids, antihistamin and cyclosporine, topical treatment, fatty acid supplements and environmental treatment. The prognosis is individual for each patient due to their different response to the treatment. It may take a while to find the right combination of treatments to achieve satisfactory control of the disease..

There are about 700 000 dogs in Sweden. Roughly 70 % of the dogs are purebred and registered in the database at the Swedish Kennel Club (SKC). The database includes records of birth date, pedigree, offspring and results from e.g. veterinary examinations related to genetic health programs.Every year approximately 10% of the dogs die; most are euthanized by a veterinarian. Dog mortality data is stored as digital medical records at animal clinics and in insurance databases.Dog owners tend to register their puppy in the SKC, but they rarely report that the dog has passed away.

This student report is about canine infectious skin diseases. It is primarily directed at veterinary assistans. The report includes a description of the skin?s structure and immunologic defences. The four types of allergic reactions are described. Different diagnostic techniques are also accounted for. The skin diseases included in the report are: fleas, lice, Sarcoptes scabiei, ringworm, Cheyletiella and leishmaniosis.

Röntgenläkarna väljer ofta att byta undersökningsteknik för att fastställa misstänkt patologi som inte går att diagnostisera med en metod. Vid röntgenundersökningar av sinus (bihålor) så kan läkaren välja mellan konventionell röntgen eller en datortomografiundersökning. Skälet är att diagnoser som tumör, benpåverkan eller ansiktstrauma inte avbildas lika bra med den konventionella metoden. Syftet med den här studien är att jämföra datotomografi och konventionell röntgen vid sinusundersökningar, vilka för och nackdelar som de olika metoderna har, hur bildinformationen och diagnostiken skiljer sig, vilka risker som finns med joniserad strålning samt vilka biologiska effekter strålningen har på människan. Intervju har gjorts med odontologi läkare som berättat om för och nackdelar med de olika metoderna, och litteratur och artiklar har gett kunskap för att komma fram till resultatet.

India is the country with the highest prevalence of rabies in the world, with about 20?000 human deaths occurring every year. The country also has a heavy burden of free roaming dogs, mainly because of the high amount of edible waste in the streets, which are the main hosts for the disease. Therefore to truly extinguish rabies, the main focus should be on the dogs, both stray dogs and owned. One method is to vaccinate all dogs against rabies.

The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

Every year an avorage of 40 000 Swedes fall ill with different forms of cancer. Chemotheraphy has an effect on the tumour cells as well as the healthy cells in the body, this causes many side effects which can be very problematic for the patient. The study was carried out in order to indicate the care measures that are taken to deal with the side effects i. e stomatit, loss of hair and sickness/vomiting, that are connected with chemotheraphy so that the outpatients will experience a quality of life. The method used was a qualitative interview with six nurses from the South if Sweden, all of whom are working with chemotheraphy patients.

Every year an avorage of 40 000 Swedes fall ill with different forms of cancer. Chemotheraphy has an effect on the tumour cells as well as the healthy cells in the body, this causes many side effects which can be very problematic for the patient. The study was carried out in order to indicate the care measures that are taken to deal with the side effects i. e stomatit, loss of hair and sickness/vomiting, that are connected with chemotheraphy so that the outpatients will experience a quality of life. The method used was a qualitative interview with six nurses from the South if Sweden, all of whom are working with chemotheraphy patients.

Den insulinlika tillväxtfaktorn II (IGF II) är ett proteinhormon som reglerar cellers proliferation, tillväxt, migration, differentiering och överlevnad. Den utövar sin biologiska funktion via IGF I-receptorn. Dess tillgänglighet för bindning till IGF-1R regleras av en familj bestående av sex IGF-bindarproteiner (IGFBPs). IGF II kan också inducera mitos via en alternativt splitsad variant av insulinreceptorn (insulin receptor isoform A (IR-A)). De cirkulerande nivåerna av IGF II kontrolleras genom IGF II-receptorn, som saknar signalfunktion och är homolog med mannos-6- fosfatreceptorn. Tystad prägling av IGF II-genen är en återkommande observation vid en utvecklingsrubbning kallad Beckwith-Wiedemanns syndrom, vilket innefattar okontrollerad tillväxt och i många fall en njurtumör hos barn, Wilms? tumör. Tillväxthämning ses vid mutationer i genlocuset hos IGF II och den närliggande genen H19 vid en annan utvecklingsrubbning, Silver-Russells syndrom.

Hästinfluensa, orsakat av ekvint influensavirus (EIV) förekommer över hela världen och är en vanlig respiratorisk sjukdom hos häst. Nyligen upptäcktes att EIV passerat djurslagsbarriären och orsakat sjukdom hos hund, vilket har lett till utvecklingen av canine influensavirus (CIV). Detta har sannolikt skett via direkt överföring utan föregående mutation av viruset. Flera faktorer spelar in i processen men den viktigaste tycks vara att häst och hund uttrycker samma typ av ytreceptorer i luftvägsepitelet (SA?2,3Gal), vilket möjliggör för EIV att binda in till och infektera cellerna hos både häst och hund.

Limb-sparing surgery aims to provide a functional pain free leg for the patient after removal of a local tumour in the leg. Reasons to perform limb-sparing instead of amputation can be arthrosis or hipdysplasia or other problems with the locomotor apparatus that makes the patient unsuitable for amputataion. Owner reluctance to amputate is another reason for limb-sparing. This master?s thesis is a case study of a dog with an osteosarcoma in its distal radius. The dog was treated by a limb-sparing method that uses the ipsilateral ulna as a vascularized roll-over autograft.