The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.

This essay answers the question: How can a manufacturing business fulfill the information demand in the processes; purchasing, production, warehousing, order and delivery?The question has been answered through different kind of studies, such as literature, documents, Internet search, interviews and observations. The essay is written from a hermeneutic point of view and by using qualitative research. The result has been validated by two different manufacturing businesses.A simple information logistic model is the result of a comparison made between theory and empery. The aim of the model is to describe how a manufacturing business can fulfill the information demand by using different methods.

Purpose: The purpose of this master thesis is to investigate how a pricing capability can be developed on a general as well as on a practical level in an industrial company working on the international business-to-business market. Methodology: We have conducted a case study of the work on pricing at Triton. After mapping the events we have evaluated the results. We have conducted interviews with people with information concerning Tritons work in the Pricing area. Theoretical perspectives: The theory includes organization and structure, pricing for the market with emphasis on transactions and theories on how to understand the customer.

Platelets are important for the healing of damaged blood vessels since they have an importantpart to play in the coagulation process. At the same time, the blood must be kept fluid and notcoagulate at the wrong time. Therefore there are factors that effect the aggregation of plateletsin a positive or a negative way.Previous investigations have shown that platelets during stirring conditions produce reactiveoxygen species (ROS) that weaken the inhibiting effect of nitric oxides (NO) on platelets andthat the drug Dexamethasone (Dex) can reduce the ROS-production.The aim of this project was to investigate if glucocorticoids, in this case Dexamethasone,could restore the inhibiting effect of NO on platelets and if there was any decrease in ROS-production.The result of the ROS-measurements showed a great variance and it was difficult to draw anyconclusions from them, but a clear decrease in ROS, as previous reported, was not shown. In the aggregation experiments the inhibiting effect of NO was observed through the drug S-nitroso-N-acetylpenicillamine (SNAP), a NO-donator.From the aggregation experiments, the result seemed to be that SNAP during longerincubation time lost its inhibiting effect, probably because the cells become desensitized.With superoxid dismutase (SOD), the effect of SNAP increased, both in the experiment withlonger and shorter incubation times. Dex seemed to reinforce the aggregation in relation toboth SOD and SNAP.

The globalisation of the world is believed by some to homogenise individuals from different national cultures. However, the values and norms of an individual are deeply rooted in their national culture and are therefore difficult to change. Since birth these values and norms are learnt through interaction with others within a specific national culture. The differences in values of a national culture are shown in the cornerstones of the nation. These cornerstones are language, aesthetics, religion and social institutions.

Titel:                                 Marknadsstrategi för lead generation: En studie om digitala marknadsstrategier och dess effekt på marknadsleadsNivå:                                 C-uppsats, kandidatexamen i FöretagsekonomiFörfattare:                        Anna Pettersen och Emma StåhlHandledare:                     PhD Agneta SundströmExaminator:                     PhD Lars-Johan ÅgeDatum:                             2014-JuniSyfte:                                Syftet med denna studie är att öka förståelsen för hur företag planerar, tillämpar och utvärderar strategier för digital marknadsföring med avsikt att generera leads.Metod:                              Flerfallstudien är av kvalitativ karaktär. Empirin samlades in genom en primär datainsamling av tio semistrukturerade intervjuer utförda på tio olika företag med verksamhet inom svenska IT-industrin. Genom ett rutnät har vi kodat och analyserat insamlad primär data för att finna teman och mönster som mynnade ut i en kärnkategori; Effekt.Resultat & slutsats:        Studien visar att de medverkande respondenterna anser att lead generation och digital marknadsföring är viktiga områden för deras företag. Respondenterna väljer att basera sin planering för marknadsstrategier på intuition och tillämpar strategier genom ?trial and error?.

Title:Knowledge system - a new way of observe the company Authors:Malin Pärmborn och Susanne Gidlöf Tutor:Anders Nilsson Department:Department of Business and Management Blekinge Institute of Technology Problem:How can processes of problem solving in a project contribute to generation of organizational knowledge in a knowledge company? Course:Master thesis in Business Economy Purpose:By describe the processes of problem solving in two different projects of our two chosen knowledge companies, we will clarify whether problem solving contributes to the generation of organizational knowledge. The purpose of this research is to increase the management consciousness concerning everyday processes that will contribute to the creation and transfer of knowledge. This is a condition to transfer human capital to structure capital and thereby decrease the company?s vulnerability. Approach:We gathered the data we needed through conversations and interviews with people on the two knowledge companies.

Problem: When opening a newspaper today there is a good chance that the headlines have something to do with recent developments in the global climate debate. This development is forcing companies to take action. The problem for many companies, including Thule, is that they are unaware of the environmental work conducted throughout their value chain and also what they need to do to become green. Thule, a company with a strong focus on profitability and growth, will not make environmental issues a part of their core strategy unless it can be shown that economic incentives exist. With this thesis we will try to build a case that will help Thule, and also other companies, see the possibilities a green venture brings with it.

The Department of Forest Products and Management, Swedish University of Agricultural Sciences has received means from Vinnova for a preliminary study of the organisation of logging work of today and how a better logging organisation should be brought about. This thesis reports results from qualitative interviews with nine forest machine contractors regarding the situation of their companies. The interviews have been analysed with respect to the genesis of the companies, which tasks they perform or that they could consider perform-ing, business relationships of the companies, relationships between the different partners of the companies, and the state of competition experienced by the contractors. The companies have developed either from the contractor previously being machine operator employee or from that the contractor in making has owned a machine and needed work. Their primary business is mechanised logging.

As the cities are becoming more crowded, the urban distribution has become a major logistical challenge. Some commonproblems in the inner cities arelimited accessibility and idling. Many of Sweden's municipalities are above the limit values for PM10limit set by the EU.Sundsvall is one of these municipalities and has the vision to create a sustainable city and region. Sundsvall LogistikparkAB is part of an EU project, SMARTSET, which is collaborationbetween several cities in Europe. SMARTSETSundsvall is about to develop a market-based sustainable model for city logistics.

I have chosen in my study, to do a comparison between pupils´ expectations of the future, how they would meet adult life or working life after their education. These pupils are ending their programmes during this term. One program is Business and Administration Programme and the other programme is Qualified Vocational Education in Business, which is a post-secondary education and training programme. This investigation is done in Haninge municipality.The purpose of this study has been to investigate if these students´ expectations differ between each other, compared with factors such as age, sex, ethnical origin and different study programmes. Further it has been interested to see how teachers and future employer meet these pupils´ expectations in education or in their planning working life.There have been two other important questions to investigate in this study.

The aim of this study has been to examine the role of control mechanisms when it comes to building relationships in a small business network. In order to reach this goal, we have performed a case study of a Swedish supplier of machines to the engineering industry, which acts as the exclusive representative of a foreign manufacturer on the Swedish market. Main results: A number of control mechanisms, both formal and informal, could be identified in the network. Their specific use, as well as relative importance differ between different actors in the network. In general, the importance of formal control mechanisms decreases as the relationship evolves over time and the importance of informal ones, mainly trust, increases in a corresponding manner..

Slutsatsen på vår problemformulering är att Boverket använder sig av olika standardiserade rapporter (mallar) som säkerställer information. Rapporterna är uppföljning av: Finansiär, kostnadsbärare och kostnadsställe. Genom att rapporterna är standardiserade innebär det att som avsändare/mottagare använder/ talar samma språk. Det innebär att när informationen från rapporterna ska kommuniceras vidare (uppåt och neråt) inom organisationen, sker det på ett mer effektivt sätt. Det i sin tur underlättar för snabbare och mer välgrundade beslut.

The Internet offers an abundance of information. This information is easy to access in technical terms, however it is difficult to find. At present there is a wide variety of search services to choose from. This master's thesis is about selecting the appropriate search service for a certain question. Are different types of services suitable for different types of questions, and if so, which services for which questions?To answer this, I have undertaken one theoretical and one empirical study.

The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.