The ability to detect protein-based biomarkers, which are linked to different diseases like colorectal cancer, is very important as a diagnostic tool. Usually complex biological samples like blood are studied which will contribute to different technical issues when performing an assay. The aim with the project is to optimize and develop the high throughput protein detection technique Proximity Extension Assay, PEA, into a 96-plex panel, in hopes of discovering an expression profile for colorectal cancer. PEA was developed by Olink Bioscience and allows specific proteins in a sample to be quantitatively transformed into nucleic acid sequences that are subsequently detected and quantified with real-time PCR. Two proximity probes containing oligonucleotide sequences bind pairwise to target protein and when brought in proximity, a DNA polymerase will extend a hybridization arm from one probe over to the second forming a double-stranded DNA sequence that can serve as a template in real-time PCR.

This paper sets out to investigate how companies can create advertisement that focus not only on selling but also on entertainment. The research is based on seven TV-commercials produced by the Swedish food chain ICA. The commercials were analyzed according to the methods of discourse analysis, semiotic analysis and rhetorical analysis. Furthermore, the research compares the analysis made with the thoughts and ideas of Tobias Karlsson, Head of marketing and communications development at ICA to find out how the comprehension of the commercials correlate with the original intentions made by the company.The study shows that ICA creates a commercial that contains the perfect mix of rhetorical approaches, communication strategies and entertainment mixed with gravity. The study also shows that ICA fails with its primary goal which is to sell selected products; however, by producing the entertaining commercials, they manage to strengthen their brand.

Husqvarna AB operates two warehouses located in the area of Jönköping. The most important task is to manage the large volume fluctuations during the peak season. DHL Exel Supply Chain (DESC) run the warehouses and the domestic transportations is outsourced to DHL Express. A number of forwarder agents are responsible for distributing the export gods. In the present situation a bottleneck occurs at the warehouse loading section, and the consequence is fulfill the time of delivery for all customer orders.

Idén till uppsatsen uppstod efter att ha läst Jan Carlsson et al: s avhandling och artiklar inom ämnet logistiskt förändringsarbete. Flera forskare problematiserar avsaknaden av teorier inom ämnesområdet samt lyfter fram bristerna i den existerande logistikforskningen som enligt forskarna inte lyckas fånga logistikförändringarnas komplexa natur.Syftet med uppsatsen var att med utgångspunkt från befintlig forskning inom området för logistiskt förändringsarbete och supply chain management, utvärdera och analysera logistiskt förändringsarbete i två företag. Utifrån befintliga teorier sammanställde vi en övergripande syntes med syfte att visa vår tolkning av hur logistiskt förändringsarbete skulle kunna hanteras. Ur denna syntes extraherade vi variabler som ansågs vara av betydelse för den empiriska studien. Undersökningen genomfördes som en fallstudie i två företag med ostrukturerade intervjuer med personer inblandade i förändringsarbetet.Resultaten vi kom fram till var att medvetenheten finns om att ta hänsyn till flera dimensioner i förändringsarbetet men det förarbete företagens utför underbygger inte alltid denna vetskap..

This paper examines Hannah Ho?chs photomontage Schnitt mit dem Ku?chenmesser Dada durch die letzte weimaren bierbauchkulturepoche Deutschlands. The paper has as its aims to understand and analyze the predominated allegorical interpretation of Schnitt and to develop a logic how meaning is produced when a viewer look at Schnitts surface. The paper finds that the predominated interpretation has been arbitrarily created out of a specific spectator that acts in a specific context and conclude instead that the predominated interpretation should be understood as a potential interpretation by a potential viewer. The paper continues to create an understanding of Schnitt as a flatbed picture to establish that as a postulate and to use it in the later semiotic dissection of Schnitts surface.

Open pit mining creates huge amounts of tailings and waste rock deposits. Due to it's content of sulphide minerals, predominantly pyrite (FeS2), there is a risk of oxidation and formation of acid water containing heavy metals, known as Acid Rock Drainage (ARD). To prevent the process of oxidation, the tailings and waste rock have to be reclaimed. The most commonly used methods of reclamation are a coverage of water or soil. Mining also results in a large-scale interference in the landscape that will make an eternal change of its appearance.

The purpose of this thesis has been to gather knowledge about the complaints of tying-up in horses and to show that the importance of feeding. The thesis includes a literature review of tying-up how preventative measures by feeding can be made. In the equine sport, crosscountry, horses occasionally suffers from tying-up, a muscle disease. An increased knowledge about the disease is demanded by riders and trainers as the disease disrupts training and competition of suffered horses. A cross-country horse works very hard in training and during competitions but the work bouts are long enough for the muscle cells to use aerobic pathways in the metabolism.

Läkemedelsbranschen är idag hårt konkurrensutsatt vilket skapar incitament till förändring av de interna processerna av vilka inköp utgör en. Läkemedelsbranschen har av tradition ansetts ha en eftersatt inköpsverksamhet för att vara en så mogen bransch. Vår undersökning gick ut på att jämföra en Best Practice modell för inköp med inköpsverksamheten i läkemedelsbranschen. För läkemedelsbranschen finns helt klart utvecklingsområden och utmaningar i förhållande till den gängse inköpsteorin och Best Practice modellerna. Vid en jämförelse med Best Practice modell för inköp och vårt fall identifierade vi ett antal avvikelser beroende på rationella, politiska och ekonomiska orsaker.

Detta examensarbete handlar om en uppföljning av en enkätundersökning enligt EFQM modellen som genomförts vid BT Products. Uppföljningen består i en djupare analys av undersökningens resultat med fokus på vissa av dess delar. De områden som huvudsakligen behandlas är företagets medarbetare, processer och ledarskap. Tyngdpunkten ligger i att klargöra orsakssamband mellan enkätens olika områden samt att gå djupare in på- och identifiera samt beskriva starka och svaga sidor hos dem. Intervjuer, observationer och statistiska metoder har använts för detta syfte vilket resulterat i att det framkommit möjligheter att förbättra verksamheten i flera avseenden. De viktigaste förslagen till förändringar är: En förändrad organisationsmodell med fokus på värdekedjor Förändrade ansvarsförhållanden och tillhörigheter En långsiktig inriktning mot en styrmodell med utgångspunkt i värden och företagskultur.

The aim of this essay is to study the religious education which the Jewish Community of Göteborg offers to members between six and fourteen years of age. The main question of the essay is ?what function does the religious afternoon education serve for the Jewish Community of Göteborg??To answer this question I have interviewed four people who in various ways are engaged in the religious education. To analyse the result I have used Danièle Herviue-Léger?s theory ?religion as a chain of memory?.

To be able to research the chain of development and its causes within military doctrines you need to describe the change and categorize it to make it understandable.This essays intent is to categorize a phenomenon within the Swedish doctrine to make it available for further research about doctrinal development. The categories are found in two of the great theorists on guerrilla warfare due to the subjects? resemblance to guerrilla tactics and its means.The phenomenon that is to be researched is directly translated as ?the free war? which basically means the use of irregular warfare behind the enemy lines. The description of ?the free war?, by whom and when it is used, are the factors that have changed during the second half of the 20th century, and have therefore been placed into different categories.