Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated SOD1 protein. Trehalose is a disaccharide which has been shown to reduce protein aggregation and increase viability in cell models and alleviate symptoms in animal models of several neurodegenerative diseases associated with protein aggregation. When given orally to the SOD1G93A mouse model of ALS, trehalose failed to slow down the disease progression, which has led to questions about the uptake and distribution of the molecule in this mouse strain. The aim of this study was to investigate whether significant levels of trehalose reach the central nervous system of the SOD1G93A mouse after oral administration. This was performed by a trehalose assay of the brain of trehalose treated animals. A glucose assay was optimised for use in small samples of brain lysate after the digestion of trehalose into glucose by trehalase, and the difference in glucose concentration before and after digestion represented the trehalose level.

Title: A study of how active therapist talks about the FMT method. FMT-therapists use music as a means of communication. The method is non verbal and uses musical codes to create a framework for the apprentice. The instruments that are being used are piano, drums, a variety of flutes and whistles. The FMT-method is a musical form of therapy that targets all functional disabilities.

The complexity of the mast cell is becoming more prominent. From being the cell recognized just to contribute to allergic inflammation it is now also associated with wound healing, protection against tumor growth and in recognition and defense against a wide range of pathogens. The location of the mast cell in the barrier between the external and internal environment of the body enables the cell to quickly respond to invading bacteria, virus and parasites. Diarrhea due to Escherichia coli infection, listeriosis, toxoplasmosis, Newcastle disease and bovine respiratory syncytial virus are examples of mast cell activating diseases that can affect animals in, as well as outside, the agricultural sector. Additionally, ticks and tick-borne diseases are of concern.

Med examensarbetet vill jag underso?ka med ett holistiskt synsa?tt pa? hela livscykeln av ljuset vilka krav en modern anva?ndare har av ett cykelljus och hur dessa anspra?k kan a?stadkommas.? Fo?r att skapa ett cykelljus som fungerar fo?r en modern cykelanva?ndare utifra?n deras krav och behov samt tar ha?nsyn till alla stakeholders fo?rva?ntningar. Fo?rst go?r jag en grundlig research pa? historiska cykelbelysningar och vad som finns idag, jag kommer att skapa ett ITK och go?ra Trendanalyser samt Brain- storming, Scenario och Personas. Sedan kommer jag att laborera med Ljust- ester innan jag ga?r o?ver till formgivningen da?r jag kommer att anva?nda mig av 3D Modeller.

Photodynamic therapy is a relatively new treatment for superficial squamous cell carcinoma in cats. There are no publications indicating that the method is being used in veterinary practice in Sweden at the present time. The method uses the interaction between a photosensitive agent which has been administered to the tumor area, light of a wavelength that can be absorbed by the photosensitiser and the presence of oxygen. In this study photodynamic treatments were performed at the Queen?s Veterinary School Hopital of Cambridge University between 1998 and 2002.

AbstractMy purpose of this essay was to discover three- and four-year-olds comprehension of their internal body and then compare the result between their ages. I have used the same methods in both essays, semi-qualitative interviews. It is structured interviews with space for following questions. My formulations of the questions were: Do the children have a comprehension of their internal structure of the body? Do the children have a comprehension of organs and organ systems? Is there any difference between the ages?Their comprehensions I have categorized in four categories and I have seen age related differences in their comprehensions.

The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.

To be preborn and treated in a hightech environment, will expose the child for an abnormal stimulance. Immature lungs and brain are accountable for the biggest healthrisks. The medical treatment will affect the childs future development. Nursing according to NIDCAP®, Newborn Individualized Developmental Care and Assessment Program, aims at reducing the surrounding disturbance in relation to the childs maturity. The aim for this literature study is to survey the affects of NIDCAP®-nursing. The literature study is based upon scientific articles.

A?mnet a?r musikterapi med hja?rnskadade personer, skrivet inom ramen fo?r Magisterprogrammet i musikpedagogik med inriktning musikterapi vid Kungl. Musikho?gskolan i Stockholm, 2012. Syftet med uppsatsen a?r att bidra till o?kad kunskap om hur det a?r att tolka och fo?rsta? hja?rnskadade personers sa?tt att kommunicera i en musikterapisituation, da? dessa har nedsatt kommunikationsfo?rma?ga, afasi, sva?rt med empati, ett utsla?tat ka?nsloliv, stel mimik och liknande.

Att studera de ekonomiska effekterna av migration är tyvärr ett för stort ämne för den är uppsatsen så vi har valt ut vissa delar av detta ämne att studera och i möjlig mån undersöka hur dessa effekter påverkar Sverige. De effekter som behandlas är effekter på tillväxt för utvandrarländer när högutbildade emigrerar och hur invandrarlandets arbetsmarknad påverkas av immigration. Vi har undersökt både teoretisk och empirisk litteratur och sedan jämfört slutsatser som dragits på internationella data med de förhållanden som råder för Sverige. Våra slutsatser är att en liten utflyttning av högutbildad arbetskraft kan medföra en positiv effekt på humankapitalsnivån i ett utvecklingsland under vissa omständigheter. Effekterna på arbetsmarknaden i invandrarlandet är omtvistade men enligt de senaste empiriska undersökningarna medför en högre invandrartäthet i en yrkesgrupp negativ påverkan för arbetskraften i denna yrkesgrupp.yrkesgrupp..

The purpose of this study was to investigate whether cannabis use can affect cognitive functions. The method that was chosen to answer the purpose of the study was a general literature review. Article search occurred in the databases PsycINFO and PubMed. Nine articles were selected based on the study?s inclusion criteria.

The purpose of this study was to investigate whether cannabis use can affect cognitive functions. The method that was chosen to answer the purpose of the study was a general literature review. Article search occurred in the databases PsycINFO and PubMed. Nine articles were selected based on the study?s inclusion criteria.

The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.

Background: Delirium is a serious condition that often affects hospitalized elder. The condition can be described as an overstrain of the brain which results in a disturbed consciousness. Elder people are particularly vulnerable since many of the risk factors develops with old age. The treatment aims to find and treat the underlying cause. Purpose: The purpose of this literature review was to illuminate factors beneficial for the nursing care of hospitalized elder with delirium.

The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.