Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly breast cancer and ovarian cancer.

Completed durability testing of gearshift gaiters at Kongsberg Automotive in Mullsjö, is sometimes leading to discussions regarding whether or not a gaiter is supposed to be a pass or a fail. That is because the current pass/fail-criterion are a bit vague. A durability test takes around 4-5 weeks to complete which is a long time if the tested material does not pass the test and a new material has to be tested instead. Stricter pass/fail-criterions and a faster testing method for the materials are therefore desired.In order to develop a durable pass/fail criteria, seven already judged gaiters were chosen. Every one of the gaiters was put through detailed analysis, after which there were a new assessment of the gaiters.

This essay is about testing the validity of an article written by Jonas Löwgren, called The use qualities of digital design. The study we have executed is about testing the featured qualities of digital design in the article on two search systems located in the library of Stockholm University and Södertörn University respectively to see how they are able to be applied on search systems. To acquire the information for the study, we handed out a written inquire among users of those systems. The result of this quantitative study shows us that many that five of Löwgrens qualities is likely to be present on the systems. Our conclusion is that five of these are appliable on search systems.

Arbetar organisationen agilt? Det är huvudfrågan i detta arbete. Organisationen har arbetat med den agila utvecklingsetoden Scrum i ett antal år. De har gjortmedvetna och omedvetna val, för att skapa sin version av Scrum. Frågan som studienförsöker svara på är om det verkligen innebär att man arbetar agilt, när man säger attman arbetar med en agil systemutvecklingsmetod..

With the huge amount of computers connected to the Internet the IP-addresses are starting to run out. The Internet Engineering Task Force, IETF, have decided that it is about time to exchange the old 32 bits Internet protocol, Ipv4, to a more modern 128 bits protocol called Ipv6. This thesis explores the possibility to install Ipv6 in different operating systems. By testing various operating systems and by set up criteria compare them to each other we give the reader a picture of how the installation is done. We also show which operating systems to prefer if you want to use IPv6.

The issue about how Scania shall perform HVAC tests in the climatic wind tunnel CD7, which Scania is about to complete by year 2013, has resulted in four test methods for truck HVAC and also a test method structure. The test methods have been chosen to focus on sun, snow and rain simulations. These are adapted and developed according to what should be tested and to what can be tested in CD7, which has been the object. With CD7 different climates can be simulated in a controlled environment for complete truck level, from desert with high sun load to arctic cold and snow.The test methods represents a basis to start from, for designers and test engineers which make the testing more repetitive as well as time eventually can be saved. Before the test methods can be applied they must be verified as they are based on theoretical and empirical assumptions.

Introduction: Dolomite AB was in need of a dummy arm for crutch testing, to complement their existing test capabilities. Background: A large number of people need crutches on a daily basis. For them it is essential that their crutches do not fail. ISO (the International Organization for Standardization) conducts ongoing work to guarantee the durability and function of e.g. crutches.

There are two species of potato cyst nematode (PCN), the yellow, Globodera rostochiensis, and the white, Globodera pallida. Each of them can appear in different pathotypes. These are separated by testing the nematode ability to multiply on a number of potato cultivars with different resistance properties. The aim of this project was to examine the virulence of Swedish and foreign PCN populations and to compare two test methods. Biotests are today the only available tests used to study virulence.

This thesis focuses on the testing activities at the stages of development and change regardingintegration brokers. The study aimed to examine the overall challenges that exist regarding thetesting activities within this context, and the thoughts towards the development method testdrivendevelopment (TDD). TDD emphasizes high level of test coverage and where the testprocess is well integrated with the development process. To seek answers to our question weapplied qualitative interviews with companies and respondents to try to understand the globalchallenges that are related to this work and processes. The main conclusions presented in thisstudy is that the overall challenges are involving and educating project participants in the testingprocess activities and the contributory effect test have on the end product.

Systems development methods has always been an important part of the systems development process. It affects not only the product, but also the organization itself. Today more and more companies are abandoning the more rigid traditional methods for the more flexible agile ones. A transition like this is bound to affect the product and the organization, but in what ways? Is it a difficult transition to make, and how does it affect social environment and dynamics? Does it change how people communicate information to each other? This study was conducted at a local branch of a larger international IT-company.

With the huge amount of computers connected to the Internet the IP-addresses are starting to run out. The Internet Engineering Task Force, IETF, have decided that it is about time to exchange the old 32 bits Internet protocol, Ipv4, to a more modern 128 bits protocol called Ipv6. This thesis explores the possibility to install Ipv6 in different operating systems. By testing various operating systems and by set up criteria compare them to each other we give the reader a picture of how the installation is done. We also show which operating systems to prefer if you want to use IPv6.

Detta arbete är en reflektion över ett programvaruutvecklingsprojekt, WAIS, och den arbetsmetodik som användes för detta projekt. Arbetsmetodiken för utvecklings-projektet var Extreme Programming (XP) och vi ifrågasätter om detta val var lämpligt för ett projekt som WAIS. Projektet genomfördes vid Blekinge Tekniska Högskola under våren 2004. Utvecklingsprojektet WAIS var en del av ett större projekt, AIS 42, som stöds av VINNOVA. Huvudprojektets bakgrund och syfte beskrivs för att läsaren skall förstå den roll projektet hade. Studenternas uppgift har varit att utveckla en prototyp för ett system som skall sprida information relaterad till logistik och transporter.

This master thesis has been done at Enea Epact AB. The purpose of this thesis is to develop and implement a Link Quality Control algorithm for GPRS/EPGRS in the current testing tool. A Link Quality Control (LQC) shall take quality values from mobile stations and base stations and decide a codingsscheme that opimizes the throughput of data. The Advantage with LQC is that it adapts the used coding scheme to the channel quality. If the channel quality is too bad for the used coding scheme, a slower coding scheme with more redundancy should be selected.

Welding is a common method for joining of metal or plastic construction parts. This report describes several different weld methods in general terms. The report focuses on the GMAW method, specifically MAG welding.A case study has also been performed for the company Wenmec. The task received from the company was to compare the mechanical properties of joints welded with the tube electrode called Nittetsu SM-3A and joints welded with the homogenous electrode called ESAB Aristorod 12.63. Both types of weld joint were welded with the MAG method with an Argon based shielding gas with 18% CO2.

The purpose of this study was to investigate the possibility of streamlining the test process by utilizing pair programming. During the process, pair programming has been practiced as is defined by the Extreme programming (XP) software development methodology, with the other aspects of XP discarded. The focus of the testing itself has been toward unit testing. The methods applied has been with an experimental approach where 93 cases were attempted to be solved by either single programmers or pair programmers. What has been investigated in these experiments was the time needed to complete a case, how many test attempts were needed to solve the case, and how high a percentage of the cases were solved.