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Complete tumour regression is the optimal outcome of cancer therapies. There are however types of tumours that naturally regress. Most of these are benign, dermatological and have an early onset in life. This literature study aims to elucidate the mechanisms behind spontaneous …
evidence and contradictory views
… stem cell theory states that there is a hierarchical organization within a tumour, in which a small subpopulation of the cells can initiate new tumours and maintain tumour growth whilst the bulk of the tumour cannot. These tumour initiating cells have shown to possess many …
Detta är en litteraturstudie av sjukdomen Devil Facial Tumour Disease (DFTD) som drabbar tasmansk djävul. De lever i vilt tillstånd på ön Tasmanien som ligger utanför Australiens södra kust. Tasmanska djävular är köttätande pungdjur i ungefär samma storlek som en rödräv. De är …
… to discover a certain pathology, for example if a the radiologist suspect a tumour in the paranasual area, he would choose to exam the patient with computed tomography. Because the CT method has several advantages in discover tumour, destruction or traumatic fractures in the …
Lymphoma is a group of malignant tumour diseases developing in the secondary lymphatic system. These diseases can develop in all organs as lymphocytes are ubiquitously in the body. In connection to mucus membranes we find mucosa-associated lymphoid tissue, MALT, in which …
… mice have confirmed the important role of WT1 in the pathogenesis of Wilms? tumour, a tumour which counts for 95% of all childhood renal tumours. In that case the WT1 gene acts as a tumour suppressor gene. Subsequent research has shown that the WT1 gene in many other cases acts …
Tumour development occurs to a large extent because of dysregulation of the cell cycle. Of particular importance are defects occurring in the G1 phase. The reason why G1 is critical is because of the influence of several signals (external signals as well as cyclins and cdks) on …
en litteraturstudie och en fallstudie i den Svenska Riesenschnauzerpopulationen
… in the nail bed can be present in the histological evaluation. The most common tumours in the nail bed are squamous cell carcinomas and malign melanomas. Also these diseases are diagnosed based on histological evaluation. Defects in the claw without any specific nail disease are …
an in vitro study of ovulation, implantation and receptivity in a mouse model
Picropodophyllin (PPP) is an analogue of the anti tumour lignan podophyllotoxin with the unique ability to selectively inhibit the receptor of Insulin like growth factor 1(IGF-1). IGF-1 is believed to play an important part in development of the endometrium facing implantation …
The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for …
… today the only clinic in Sweden to offer radiation therapy as a treatment of tumours. The body contains of billions of cells that all have to obey the regulations that are established. If a cell is exposed to a harmful substance, for example a chemical, it can be transformed …
Determination of serum thymidine kinase 1 (TK-1) activity is used as a tumour marker in both human and veterinary medicine. TK-1 is an intracellular enzyme involved in a salvage pathway of DNA synthesis. The expression of TK-1 is cell cycle dependent and the activity increases …
… The expression of serglycin in dogs remains to be explored. As mast cell tumours are common in this species, it would be of interest to find out whether serglycin can be used as a marker for these tumours, to facilitate diagnosis and prognosis as well as evaluation of how well a …
… can arise in a variety of extra nodal sites. Previous studies indicate that tumour arise from more mature B-cells.Our purpose was to examine the presence of clonality and somatic hypermutation of immunoglobulin (IgV?) of MALT lymphomas.Paraffin-embedded tumour samples from13 …
… fall ill with different forms of cancer. Chemotheraphy has an effect on the tumour cells as well as the healthy cells in the body, this causes many side effects which can be very problematic for the patient. The study was carried out in order to indicate the care measures that …
