Lameness localized to the hoof is a common problem in horses. Magnetic resonance imaging (MRI) as a diagnostic tool is becoming more common and is well suited for examination of the distal limb and the hoof capsule. Today there are two different methods of MRI where in one the horse is under general anesthesia and in the other the horse is standing and only sedated. In this study we have compared the visualization of the distal interphalangeal joint using these two methods in two different groups of horses with unknown clinical problems referred to two different equine hospitals. The width of the joint structures including thickness of joint Cartilage and joint fluid and also the width of the dorsal pouch of the distal interphalangeal joint were measured.

This is a survey of non-traumatic skeletal abnormalities of the domestic cat. The types of diseases that are presented are congenital, developmental, metabolic, degenerative, neoplastic, inflammatory, infectious and a few diseases of uncertain aetiology. Each disease, where possible, is described in aetiological, symptomatical and radiological aspect. In the cases where there are plausible treatments these are presented..

Joint injury (inflammation) or osteoarthritis is the most common cause of poor performance in the athletic horse. Osteoarthritis is the ensuing degeneration of joint Cartilage due to inflammation/injury. The single most important factor in the inflammation cascade of joint injuries is interleukin-1 (IL-1). Until recently, these injuries have been treated with products like hyaluronic acid, cortisone and polysulphated glycosaminoglycans (PSGAG). Several studies have not been able to demonstrate a significant difference in the clinical improvement of joint injuries treated with hyaluronic acid or PSGAG and saline.

In cooperation with Hälsoteamet Halmstad a pilot study was made to see if whole body vibration exercise has any effect on muscle strength, movement and experience of pain in people with knee osteoarthritis. Today whole body vibration exercise is a revolutionary exercise method that needs more studies to show the positive and negative effects. Osteoarthritis is a degenerative disease where more Cartilage is destroyed than replaced. The most common symptoms are pain, stiffness, restricted movement, muscularly atrophy, tenderness and instability. The Cartilage needs pressure to rebuild, it is therefore important that the patient exercise.

Osteoartrit (OA) är en vanligt förekommande sjukdom och bidragande faktor till nedsatt förmåga att träna och tävla hos hästar. Ledinflammation som det också kallas drabbar alla häst raser och i alla grenar inom rid, trav och galoppsporten. Inflammationen kan drabba alla de ingående strukturerna i leden och ger kliniskt upphov till hälta, smärta, ökad ledfyllnad och stelhet. Sjukdomen bidrar till sämre djurvälfärd och ekonomiska förluster inom hästindustrin. Orsakerna kan vara många.

On average half of the sows in Swedish piglet producing herds are culledannually. A significant portion of the sows are euthanized because of lameness orparalysis. Young sows and gilts are overrepresented in the category of animals,culled due to injuries in the musculoskeletal system. These injuries cause pain tothe animals. Early culling of sows/gilts also have economical consequences forthe producers.

The determination of the optical properties of biological tissue is an important issue in laser medicine. The optical properties define the tissue´s absorption and scattering behaviour, and can be expressed by quantities such as the albedo, the optical thickness and the anisotropy coefficient. During this project, a measurement system for the determination of the optical properties was built up. The system consists of a double integrating sphere set-up to perform the necessary reflection and transmission measurements, and a computer algorithm to calculate the optical properties from the measured data. This algorithm is called Inverse Adding Doubling method, and is based on a one-dimensional transport model.

Rheumatoid arthritis is an autoimmune disease, where joints are attacked by the own immune system, leading to chronic inflammation and destruction of bone and Cartilage. Inflammation is a complex process, controlled by many different substances. One of them is adenosine, which has anti-inflammatory properties. In this project, three polymorphisms in different genes, involved in synthesis and signaling of adenosine, were genotyped for 188 patients with RA and 362 controls without RA. The results shows that for the polymorphism in A2a, a gene coding for an adenosine receptor, there was no significant difference in genotype distribution between the groups.

Background: Rheumatoid arthritis is a common disease worldwide. The disease is described as a chronic inflammation that afflicts mainly the joints, the tendrons and the synovial joint. The inflammation breaks down Cartilage, ligaments and bone. When the patient gets the diagnosis he/she frequently reacts with chock, denial or/and dissociation. Active support from the nurse can have an important impact on the patient in accepting and processing that he/she suffers from disease.

Phenylbutazone has been discussed in the world of the equestrian sport several times and different countries have diverse opinions on its use in competitions. The progressive list that permits phenylbutazone with plasma levels up to 8 µg/ml was presented at the FEI General Assembly in November 2009. The list was voted to be accepted, but later several countries realized the consequences and after protests the list was rejected and is going to be discussed again at the FEI General Assembly 2010. In this literature study I have studied the relationship between the concentrations of phenylbutazone in plasma and the effects on lameness. The purpose was to establish whether the limit of 8 µg/ml phenylbutazone in plasma affects the equestrian sport.

The aim of this study was to compare the effect between the drugs rituximab and infliximab in rheumatoid arthritis (RA). RA is an autoimmune disease that affects the peripheral joints and is associated with exacerbations. Various immune reactions in the body cause inflammation of the joints which further results in Cartilage and bone damage. The diagnosis is made by the classification system "The 2010 American College of Rheumatology (ACR) / European league against rheumatism (EULAR) classification criteria for rheumatoid arthritis", which is an update of the older system called "The 1987 American College of Rheumatology classification criteria for RA". Approximately 0.5-1% of the population is developing the disease, but it varies slightly between different parts of the world.

Several bulls in Sweden are culled because of lameness. Studies of beef bulls have shown that osteochondrosis is an important underlying cause of hind limb problems (Persson, 2003; Dutra, 1998). Osteochondrosis in horses, dogs, swine, poultry and man are well documentated in the literature, but there are few studies in cattle. The prevalence of osteochondrosis in dairy bulls in Sweden is unknown. The aim of this study was to investigate the presence and localisation of osteochondrosis in the hindlimbs of dairy bulls. This study consists of 48 one-year-old bulls divided into four groups related to which farm they came from.

Magnetic resonance imaging (MRI) has the potential to be used for the diagnosis and study of osteoarthrosis in the equine tarsal region. In the development of new diagnostic MRI techniques cadaver specimens are often used. To allow the use of cadaver legs for these types of studies it is important to know the effect of time after death on the MRI image. Since the relaxation times are temperature dependent, it is interesting to examine whether the time after death and the temperature of the cadaver may play a role in the image appearance and quality. The radio pulse sequences that show the different types of tissues are also important to know when pathological evaluation with MRI is used.

Magnetic resonance imaging (MRI) has the potential to be used for the diagnosis and study of osteoarthrosis in the equine tarsal region. In the development of new diagnostic MRI techniques cadaver specimens are often used. To allow the use of cadaver legs for these types of studies it is important to know the effect of time after death on the MRI image. Since the relaxation times are temperature dependent, it is interesting to examine whether the time after death and the temperature of the cadaver may play a role in the image appearance and quality. The radio pulse sequences that show the different types of tissues are also important to know when pathological evaluation with MRI is used.