Middle East respiratory syndrome coronavirus (MERS-CoV) är ett virus som först observerades hos en patient år 2012 på ett sjukhus i Saudiarabien. Viruset orsakar luftvägssymptom och ibland gastrointestinala symptom. Dödligheten hos människa är över 30%. Eftersom tidigare erfarenhet har visat att nya coronavirus ofta har sitt ursprung i en djurpopulation har många studier gjorts för att undersöka spridningen av MERS-CoV och förekomsten av en eller flera reservoirer. Denna litteraturstudie har som mål att undersöka vilka bevis det finns för dromedarens roll i smittspridningen av MERS-CoV. Då flera seroepidemiologiska studier gjorts som visar att MERS-CoV eller ett nära besläktat virus har cirkulerat i dromedarpopulationen i över 20 år har man gått vidare och undersökt bl.a.

The task was to design and manufacture a submersible displacement pump working with the wobble plate principle. The main task for the Wobble plate pump is to be used as a sewage pump for smaller households or dewatering pump in environments where small flows and high pressures are acquired. For these purposes ITT Flygt sell a screw pump, PC-Grinder 3068. The hydraulic part of the PC-Grinder is manufactured by a subcontractor. Therefore ITT Flygt wants to evaluate an alternative to their screwpump PC-Grinder, which can be entirely manufactured by them self.

This study had two different aims. The main aim was to investigate the dynamics and impact of African swine fever (ASF) on a farm in Uganda during a recent outbreak through a case study. The second aim was to estimate the presence of two important differential diagnoses of ASF: Classical swine fever (CSF) and Porcine Reproduction and Respiratory syndrome (PRRS).The field and laboratory based case study of the farm level dynamics of ASF virus during a recent outbreak (October-December 2010) on a farm in the district of Mityana, Uganda, was conducted, using interviews, ELISA and RT-PCR. The financial impact on the farm was also estimated. The impact of the outbreak was profound.

Utbrott med pneumoni i kalvbesättningar är förenat med både ökade arbetsinsatser och produktionsförluster för djurägaren. Av den anledningen är det av intresse att hålla sjukdomsutbrotten nere, något som ibland är lättare sagt än gjort då många olika infektionsagens samspelar med såväl miljöfaktorer som kalvens egen fysiologi vid etablering och spriding av luftvägsinfektioner.I den här studien ingick 30 förmedlingskalvar av mjölkras som ursprungligen köptes in från 10 olika besättningar för att ingå i ett försök på Sveriges lantbruksuniversitet (SLU) i Uppsala. Strax efter att kalvarna anlänt till stallokalerna insjuknade majoriteten av dem med varierande grad av luftvägssymptom, lös avföring/diarré och nedsatt allmäntillstånd, något som är mycket vanligt då kalvar från olika besättningar integreras. De kalvar som visade påtagliga symtom på luftvägsinfektion behandlades med penicillin-prokain. Blodprov togs från alla individer i samband med ankomst samt 19-34 dagar senare strax innan avlivning.

Bovine viral diarrhoea virus (BVDV) is the causative agent of a complex of disease syndromes in cattle with high economical and welfare impacts. BVDV occurs as two biotypes; cytopathic (BVDVcp) and noncytopathic (BVDVncp) determined by differential effects on cultured cells and can also be divided into two genotypes (BVDV1 and BVDV2) on the basis of genomic diversity. The interaction between BVDV and the host?s immune system is regarded a key aspect in the sequel of BVDV infection. Infection with BVDV normally causes an acute transient infection, with mild to subclinical signs, but occasionally results in severe and even fatal disease.

This study had two different aims. The main aim was to investigate the dynamics and impact of African swine fever (ASF) on a farm in Uganda during a recent outbreak through a case study. The second aim was to estimate the presence of two important differential diagnoses of ASF: Classical swine fever (CSF) and Porcine Reproduction and Respiratory syndrome (PRRS).The field and laboratory based case study of the farm level dynamics of ASF virus during a recent outbreak (October-December 2010) on a farm in the district of Mityana, Uganda, was conducted, using interviews, ELISA and RT-PCR. The financial impact on the farm was also estimated. The impact of the outbreak was profound.

When investigating mechanical problems it is often more convenient to deal with scalars rather than vectors. In this project methods stemming from the field of analytical mechanics, which lets one derive the equations of motion using scalar quantities instead of vectors, have been used. Two mechanical problems were investigated, a double pendulum with a spring and particles orbit in a sphere. The equations of motion of the two systems were derived with the assistance of computer algebra, using Maple and the external package Sophia. The systems were investigated with regard to periodicity and conserved quantities..

African Swine Fever (ASF) is one of the most serious transboundary swine diseases because of its high lethality for pigs, socioeconomic consequences, rapid and international spread and the absence of either treatment or vaccine. This Sida Minor Field Study (MFS) was carried out during fall 2010, as part of a larger collaborative research project called ASFUganda, focusing on the epidemiology of the disease in Uganda. The aim with this study was to get more knowledge about the pathology in cases of ASF in Uganda, by studying macroscopic and microscopic lesions in pigs with acute and chronic ASF and to detect the ASF virus (ASFV) in tissues by immunohistochemistry. The pigs were selected from the two different geographical locations in Uganda, Mityana and Gulu district, both with on going confirmed outbreaks of ASF. Necropsies were performed in the field, and the laboratory procedures at the JICA (Japan International Cooperation Agency) Veterinary Pathology Laboratory, Entebbe, Uganda, and at the Department of BVF, SLU, Uppsala, Sweden. Three pigs from an outbreak of ASF in Mityana district showed both the history and the clinical symptoms typical for ASF.

Under åren 2005-2010 utförde en forskargrupp från Colorado State University studier på vaccinerade katter och fann att katter utvecklade antikroppar mot sina egna njurar efter vaccination med vanligt förekommande basvaccin mot parvovirus, calicivirus och herpesvirus. Virus till vaccinen är odlade på en celllinje från kattnjurar och går under benämningen Crandell Rees Feline Kidney. Antikropparna riktade sig mot antigen identifierade som annexin II och ?-enolas och man såg tecken på interstitiell nefrit hos 50 % av katter som hyperinokulerats med Crandell Rees Feline Kidney. Hos människa och mus har antikroppar mot ?-enolas och annexin II kopplats till autoimmuna sjukdomar och då framförallt immunologiska reaktioner mot njurcellerna.

Boskapspesten (eng. Rinderpest) deklarerades den 25e maj, 2011, vara utrotad från jorden. Det gör den till den andra infektiösa smittan människan utrotat. Sjukdomen är en av de äldsta noterade boskapssjukdomarna och har under historien orsakat miljontals dödsfall av nötboskap och mindre idisslare. Rinderpestviruset är ett höljeförsett, enkelsträngat, negativt RNA-virus, tillhörande genuset Morbillivirus, familj Paramyxoviridae. Sjukdomen det orsakar är mycket smittsam, med en mortalitet på upp till 90% i vissa fall.

Scrapie is an infectious neurologic disease in sheep caused by prions, corresponding to transmissible spongiform encephalopathies (TSEs) in other species. The prion is presumably constituted of PrPSc, the misfolded form of the normal endogenous prion protein, PrPC, which is found in practically all cells in the body. PrPSc can induce a conformational change in PrPC and misfold it as an imprint of itself; this is how prions amplify and spread. The process of conformational change is poorly understood and there might exist intermediate forms between PrPC and PrPSc. Bioassay using mice has traditionally been the golden standard in prion studies but is limited by cost and time.

Kraven på hög kvalité och höga skördar har länge varit en drivkraft för att effektivisera och utveckla växtodlingen. Lantbrukare har i alla tider försökt att minska de negativa effekter som ogräs, insekter, svampar, bakterier och virus har haft på skörden. Bekämpningen har sett olika ut genom åren och utvecklats utifrån kunskaper om skadegörarna och ogräsen. Växtföljder, jordbearbetning samt bekämpning kemiskt och mekaniskt är idag de främsta åtgärderna. Målet med denna litteraturstudie är att ge en klarare bild av samspelet mellan besvärliga växtpatogener och dess värdväxter i dagens svenska lantbruk. På detta vis kan man dra slutsatser om huruvida ogräsfloran på ett fält har betydelse för vilka svamp- och virussjukdomar som kan tänkas uppkomma på detta fält. Studien visade att flertalet svampsjukdomar och virusinfektioner kan drabba flera av våra vanligaste åkerogräs, men även arter som odlas i vall kan angripas.

An Internet application, VEDAIR, for estimation of air quality in regions with small-scale combustion of bio fuel has been developed by Swedish Meteorological and Hydrological Institute with financing from Swedish Energy Agency and Swedish Environmental Protection Agency. The model contains user interface and a coupled model concept where concentrations of atmospheric pollutions are calculated for regional, urban and local contributions. In this report the model is described and a first study of air quality considering PM10 (particles with a diameter less than 10 µm) in two Swedish municipalities, Vänersborg and Gnosjö, is introduced.According to the result, there are areas with poor air quality even in smaller Swedish municipalities, mostly due to high emission from buildings with older wood heating furnace without hydraulic accumulator.In Vänersborg three areas were analysed in VEDAIR for the year 2003: Vargön, Mariedal and the downtown district. In the whole municipality the upper evaluation threshold for PM10, which is defined as 14 µg/m3 for annual average, was exceeded due to background contribution of particles. In all areas, however, the concentrations of PM10 were less than the environmental quality norms.

At the end of April 1986 reactor number 4 of the nuclear power plant at Chernobyl explod-ed and large amounts of radioactive particles were then released into the atmosphere due to both the explosion as well as the consecutive fire of the graphite core. A cloud of radioac-tivity was spread over the northern hemisphere, including Sweden, due to the prevailing wind directions. The radioactive particles were washed out from the cloud by rain and snowfall in some areas of Sweden and deposited on the ground. The deposited radionu-clides, primarily cesium and iodine isotopes, were later absorbed into the soil and taken up by the roots of the plants. Some of these radionuclides, like 137Cs, still persist in some of the terrestrial ecosystems at relatively high concentrations which lead to contamination of the meat of moose, roe deer and wild boar even today.The two municipalities Heby and Uppsala, in the eastern part of central Sweden, experi-enced a relatively large deposition of 137Cs which resulted in high levels of 137Cs in moose and other game.

Emerging infectious diseases are a recurring threat to both human and animal health. Understanding the multiple causes behind the emergence of new diseases is key to the prevention of new and potentially devastating outbreaks. The list of underlying causes is long, including a variety of anthropogenic, environmental, molecular and climatic changes that promote the emergence and spread of disease. Two of these factors are central to the emergence of new diseases and receive special attention in this study. The spread of disease from wildlife to livestock and diseases that spread from animals to humans (zoonoses) are of importance as they implicated in the majority of EID events.