Background: As a part of a national health control program, Statens VeterinärmedicinskaAnstalt performs diagnostics to screen flocks for certain pathogens causing high mortality,morbidity and/or serious economical losses. There are several viruses in the programincluding IBDV (infectious bursal disease virus), IBV (infectious bronchitis virus) and NDV(Newcastle disease virus). Method: 96 serum samples were collected from different poultryflocks in Sweden and analyzed by ELISA, which are currently used in the health controlprogram as well as by a commercial prototype of a multiplex immunoassay manufactured byLuminex Corp., which is currently under evaluation at the United States Department ofAgriculture USDA. This 4-plex assay detects antibodies for the three above-mentionedviruses as well as antibodies of avian reovirus. In the context of this study the ELISAs run inroutine diagnostics as well as a REO ELISA were used as the standard for comparison.Result: The antibody concentration in serum from vaccinated chickens was high while theantibody concentration level in serum from not vaccinated chickens was low.

Feline infectious peritonitis (FIP) is a disease that can affect cats and is caused by a feline coronavirus (FCoV). FCoV is spread via the feacal-oral route and many cats are carriers of the virus. Despite that, very few of the carrier cats develop FIP. The explanation of this phenomenon is that the virus has to mutate to be able to cause FIP and in the majority of the carrier cats this mutation never occurs. FIP is very hard to diagnose because the symptoms are diffuse and a completely accurate diagnosis can almost exclusively be established during a postmortem necropsy.

Emerging infectious diseases poses a great future threat, not only to humans but also to domestic animals and wildlife. Even though the majority of these infections only cause minor health problems, the relatively recent emergence of HIV clearly illustrates that the next major human pandemic may surface at any time. Regardless of what the name indicates, most emerging human pathogens are not believed to be recently evolved, but to have existed previously in the natural environment. Most emerging pathogens are zoonotic, i.e. able to infect animals besides humans.

We derive the equation linking the Weyl tensor with its Lanczos potential, called the Weyl-Lanczos equation, in 1+3 covariant formalism for perfect fluid Bianchi type I spacetime and find an explicit expression for a Lanczos potential of the Weyl tensor in these spacetimes. To achieve this, we first need to derive the covariant decomposition of the Lanczos potential in this formalism. We also study an example by Novello and Velloso and derive their Lanczos potential in shear-free, irrotational perfect fluid spacetimes from a particular ansatz in 1+3 covariant formalism. The existence of the Lanczos potential is in some ways analogous to the vector potential in electromagnetic theory. Therefore, we also derive the electromagnetic potential equation in 1+3 covariant formalism for a general spacetime.

Bull terrier hereditary nephritis is caused by a mutation that leads to an inadequate synthesis of collagen type IV, which is an important component in the basement membranes. The inheritance of the mutation is autosomal dominant in bull terriers and progression to renal failure takes variable time, from several months to ten years. Proteinuria is the first clinical sign of the disease and the diagnosis is confirmed by transmission electron microscopy of renal tissue where typical ultrastructural changes in the glomerular basement membrane (GBM), thickening and multilaminar splitting are found. This study was performed in order to find out the occurrence of hereditary nephritis in bull terriers in Sweden through examination of urine samples and renal tissue and comparisons with how the disease is described in the literature. Urine samples from 76 Swedish bull terriers were collected and examined for proteinuria.

This study aims to highlight the crisis and adjustment process in individuals who suffered myocardial infarction. The research questions focus on the informants? experiences of the crisis and life adjustment process, and illuminate the coping strategies that the informants describe important. By using a narrative method and applyingthe crisis theory and coping theory as theoretical guidelines, this study endeavors to illuminate individuals' experiences of the disease from their own perspective. The empirical material consists of four life stories gatheredthrough semi-structured interviews.

The purpose of this study was to describe the experiences of being a family caregiver for aperson with dementia. A further aim was the inclusion criteria and data collection methods inthe studies presented, and how this may have affected the results of the studies. The methodwas a descriptive literature study with qualitative approach. Data were collected throughdatabases Cinahl and Pubmed using the words: dementia, knowledge, information, support,caregivers, coping, spouses, experiences and family caregiving. Keywords were combined indifferent ways in order to refine the search.

Background: Quality of life is a concept of individual meaning which is perceived differently depending on the person experiencing it. To have a chronic disease in the lung, such as asthma, has an effect on the quality of life. Asthma affects people of all ages. It is a disease that causes a constriction in the patients? airways which leads to a feeling of suffocation which in turn produces a feeling of anxiety.Aim: The purpose is to illuminate which factors affect the quality of life in adult patients with asthma.Method: This is a literary review based on ten articles, both quantitative and qualitative, from four different continents.

The mountainous Central Asian and former Soviet country Tajikistan is the least advantaged country economically among the former Soviet Union states. Approximately 6.5 % of the land is arable in a country where roughly 80 % of the households typically own small numbers of sheep and goats. Management practices and animal husbandry in the villages such as uncontrolled breeding, mixing of animals on pastures favor transmission of infectious diseases. Brucellosis is a zoonotic bacterial disease caused by Brucella spp. The disease is endemic in Tajikistan. B.

The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.

This study was performed in order to investigate the difficulty in diagnosing retrobulbar disease with ultrasound. A retrospective study was accomplished to investigate the use of ultrasound in patients with suspected retrobulbar problems, and how often the examination is diagnostic. The computer based patient files, at the University of Agricultural Science in Uppsala, were searched for dogs with suspected retrobulbar disease. During 1999-01-01-2004-04-14, 14 patients fulfilling the search criteria were found. The patient records were studied, and the written reports from the ultrasound examinations were compared with the printed pictures from the examinations.

White-Nose Syndrome, WNS, is an emerging fungal disease in the Northern American bat population causing mass mortality in infected hibernacula. Geomyces destructans is a newly discovered psychrophilic fungus causing WNS but the pathogenesis and epidemiology of the disease is not yet fully clarified. Geomyces destructans has been found in Europe but has not been a cause of mass mortality there. This study is the first investigation done to see if G. destructans is present in Sweden.

Sahlgrenska Academy at University of Gothenburg Department of Internal Medicine and Clinical NutritionAbstractTitle: Alpha-linolenic acid from flaxseed oil and effects on blood pressure ? A systematic reviewAuthor: Christine Hårdfelt och Liduina van SitterenSupervisor: Helen LindqvistExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: April 9th, 2014Background: High blood pressure is strongly associated with an increased risk of developing cardiovascular disease, particularly stroke. ALA-fatty acids have previously been associated with decreased blood pressure. Flaxseed oil is very rich in these fatty acids and has also been highlighted as an affordable and sustainable source.Objective: To investigate whether ALA-fatty acids from flaxseed oil may affect blood pressure in people with high risk for cardiovascular disease.Search strategy: Two searches in PubMed and Scopus were performed. The sample was specified by using specific keywords.Selection criteria: The criteria for inclusion of studies required that flaxseed oil was compared with a control and that blood pressure was measured as an endpoint.

Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.

Bakterien Brenneria salicis lever i xylemet hos bland annat arter av Salix. Under vissa omständigheter ger den upphov till en vissnesjuka, internationellt känd som Watermark Disease. Utbrott av denna har aldrig rapporterats från Sverige, men då forskning visat att bakterien ofta uppträder som endofyt och inte patogen uppstår frågan om själva bakterien ändå inte finns i Sverige utan att orsaka vissnesjuka. Samma forskning visar nämligen att yttre faktorer kan förmå bakterien att övergå från en endofytisk till en patogen livsstil. Under antagandet att klimat och markanvändning är sådana faktorer och vetskapen att de är i förändring blir det angeläget att undersöka B.