Today, there are more than 12 000-14 000 farms worldwide using an automatic milking system (AMS). Studies have shown that transition to AMS affects the udder health of cows adversely, recognized primarily as elevated somatic cell counts. There are several reasons for this, for example the greater variation in milking frequency seen in AMS. On one hand, short milking intervals may lead to bad teat condition of the cows due to the stress the milking procedure exposes the teats to. Too long milking intervals, on the other hand, seem to predispose for milk leakage, which is, in turn, a risk factor for the development of mastitis.

The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

Denna projektrapport är avsedd att vara ett hjälpmedel för SiCell, en del av SciLifeLab Uppsala som ska bli Europas första plattform för enkelcellgenomik till hösten 2013. SiCell har bett projektgruppen om undersökningar gällande ett Laboratory Information Management System, LIMS. På svenska ett datahanteringsystem för laboratorier. Ett sådant system skulle kunna effektivisera SiCells verksamhet. Undersökningarna har resulterat i en kravspecifikation som ett LIMS för SiCell ska uppfylla och en sammanställning av tillgängliga mjukvaror som bäst uppfyller dessa krav.

A numerical simulation case involving space plasma and the evolution of instabilities that generates very fast electrons, i.e. approximately at half of the speed of light, is used as a test bed for scientific visualisation techniques. A visualisation system was developed to provide interactive real-time animation and visualisation of the simulation results. The work focuses on two themes and the integration of them. The first theme is the storage and management of the large data sets produced.

Mastocytom är den vanligaste typen av kutana tumörer som ses hos hundar, och utgör 7-21 % av hundens alla hudtumörer. Majoriteten av alla mastocytom hos hundar uppstår i dermis eller i subkutan vävnad. Etiologin bakom uppkomsten av kutana mastocytom hos hundar är fortfarande inte helt klarlagd, och den är förmodligen multifaktoriell. Syftet med den här litteraturstudien är att diskutera olika mekanismer som kan ligga bakom utvecklingen av kutana mastocytom hos hund. Studien tar även upp frågan om det finns en genetisk predisponering hos vissa hundraser. Mastceller härstammar från hematopoetiska stamceller.

Feline odontoclastic resorptive lesion (FORL) is a tooth disease affecting both domestic and wild cats. Although FORL was described as early as the 1920´s, the etiology is still unclear. Several hypotheses have been presented but different studies have obtained contradictory results, and today there is no generally accepted etiology. Teeth affected by FORL are characterized by root resorption with progressive destruction of the tooth structure and alveolar bone as a consequence of clast cell activity. The disease is considered very painful when reaching a certain stage.

Background: Patients with cancer of the lung have to endure a quantity of physical, psychological and social difficulties. In their exposed position they are in need of help and support to pull through the situation. With the knowledge of factors effecting lung cancer patients? quality of life, it will be easier to give the help and support they need. Aim: The aim of this study was to describe factors effecting lung cancer patients quality of life from the patient?s perspective.

The PhonePages of Sweden is a company that develops software for mobile units, especially cell phones. This thesis treats the development of, and contingencies for, a mobile phone directory, using the limited resources found in a mobile unit. The project was implemented and executed at The PhonePages with the intention of creating a product to sell to a third party.By studying different solutions, their benefits and drawbacks, an abstract picture of the product was constructed. Problems covered include compatibility problems caused by todays platform diversity as well as problems with saving, organizing and presenting data.The main goal was to create a phone directory which does not make external information retrievals. The service should contain both company and personal information, with name and phonenumber.

Hemoglobin is an oxygen binding protein in erythrocytes. Hemoglobin is composed of four polypeptide chains. During the fetal stage the type of hemoglobin called fetal hemoglobin (HbF) dominates. After birth HbF is replaced by adult hemoglobin (HbA). HbF persists in concentrations less than 1%.

Apart from recognizing and neutralizing threats, antibodies also have the ability to regulate immune responses against their specific antigen. IgG administered together with erythrocytes is well known to induce >99% suppression. This has been used to prevent haemolytic disease in new-borns since the 1960's, but the mechanism behind it is still not completely understood. The effect on the primary response is well established, but its influence on induction of immunological memory is still heavily debated. In this study adoptive cell transfer of splenocytes to irradiated mice was used to survey the effect IgG has on induction of immunological memory without disturbance from the primary IgG response.

The aim of this Master?s thesis is to examine how the lifestyle of youth between the ages of 15-17 is influenced by electronic media and also what view and opinions youth has regarding electronic media and lifestyle. We intend to examine how and when the youth use electronic media in their everyday lives, what purpose the electronic media has in the life of the youth, and finally what views and opinions regarding electronic media and questions regarding lifestyle the youth express. We as librarians and adults need more knowledge on how youth use electronic media and also what thoughts they have regarding media and lifestyle. We would like to bring some knowledge to the discussion in this area with our study to librarians as well as parents.

Today digital guides are most frequently used by the museum and tourism industries. They are also used for education purposes. They make it possible to distribute information and have it easily accessible. In addition to written information they add sound, pictures and videos which lift the whole impression of the visited place to a higher level. A variety of systems currently in use today have been evaluated.

ABSTRACT Infertility is a medical condition that affects approximately 16 % of Swedish couples in childbearing age and is a condition found in both men and women. When a couple has been trying to conceive for more than 12 months without success they need to see a health care provider. Infertility can be treated with medicine, insemination or assisted reproductive technology such as in-vitro fertilization (IVF) and intra-cytoplasmic sperm injection (ICSI). The aim of this study was to validate a morphokinetic selection model, KIDScore? D3 Basic, against morphological selection model that is currently in use at the Fertility unit at University hospital in Orebro.

VBG Produkter AB is a process-orientated company that develops, manufactures and markets trailer couplings with belonging coupling equipment, protection equipment against skidding and stands for wagon-bridge for heavy vehicles. The company feels that their set-up time in production for couplings is not at an acceptable level. Due to high demands of customer oriented production the intermediate stock level of included products within the assembly of couplings has gradually increased which has resulted in high inventory holding costs. VBG Produkter applies Kanban in their production, therefore it is important to produce exactly the necessary amount and avoid overproduction. The objective of this project is to suggest appropriate solutions so that VBG Produkter is able to reduce their set-up time in assembly of couplings, by identifying internal and external set-up time for the chosen process bushing cell.