Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly breast cancer and ovarian cancer.

The aim of this study has been to examine six books about Oscar Wilde?s homosexuality during the years 1906 ? 2003. I have been analyzing their descriptions about his sexual orientation and compared them to each other to see the changes through time. In order to see some clear changes the main focus was to choose time differences between the books. It was clear that the earlier writers had negative opinions and thoughts about his sexual deviation the way they described it.

The purpose of this work is to design and construct a device able to measure the mechanical attrition of oxygen carrier particles. Those particles are used in chemical looping combustion and in the present situation there is a lack of knowledge in how the attrition process work and in which extension. To find already tested solutions trying to answering this problem a literature study wascarried out and the best solution found was the so called Grace-Davison Jet-Cup method. This method is supposed to emulate the attrition caused by a cyclone separator and its advantages are that it is possible to use small test amounts, 5-10 g, and a thirty minutes long test will be enough to acquire useable results. An device was designed based on the Jet-Cup method with some slight modifications.

Projektet behandlar det sublima i relation till arkitektur; både som händelse, diskurs och institution. Genom ett event som dynamisk förskjuter arkitekturens parametrar och sätter dessa i kontinuerlig förändring i relation subjekt-tid och objekt-rum. Ett gränsöverskridande erfarande av arkitektur..

If Sweden want to be able to compete internationally with its production capacity,it is important to work actively with production development and production ofresource-and time-efficient. This report is a bachelor thesis of 15 hp conducted atthe University of Halmstad. Using the principles of continuous improvement andLean Production, the author developed a concept for HAGS Aneby AB to changeto the customer order driven assembly of spring toys.First of all, the theories of Lean Production, logistics and ergonomics are used tobuild and present a theoretical framework for further examination. Then, toachieve the target, the current assembly process is analyzed to develop some firstconceptual ideas for improvement. In order to develop the best advice, theconcepts are evaluated against the company?s requirementsThe developed action plan gives recommendations on how the company shouldrestructure their assembly process and the organization of the related departmentin order to produce spring toys in a more time efficient and lean way.

This paper studies the relationship between individual characteristics of displaced workers and the probability of re-employment. A competing risks hazard model is used, distinguishing between exits from joblessness to self-employment and to paid-employment. All individuals between 25 and 55 years of age, at the time of displacement, that suffered from at least one year of joblessness after being displaced between 1990 and 1998 due to establishment closures that occurred between 1990 and 2001 are included. This allows for the closure procedure to be between one and three years long. Each individual is followed, from the year of displacement until the year of re-employment or at the latest, ten years after displacement.

Allt fler företag väljer att vara webbaserade och ägna sig helt till e-handel. Samtidigt fortsätter antalet e-handelsföretag att öka i antal kraftigt. Företagens behov av personlig information och kunddata har även ökat för att förbli konkurrenskraftiga. Vilket skapar ett problem, behovet av denna personliga information hos företagen riskerar att inkräkta på användarens personliga integritet. Tidigare forskning presenterar inte mycket angående värdet av den personliga integriteten och de fördelar ett skyddande av detta genererar.

In todays high-technological society where the Internet plays a central role in our day-to-day life, many e-retailers are not able to attract customers to complete a transaction on their website. In order to succeed, many e-commerce sites must improve several safety aspects regarding online payment, in order to be perceived as a reliable and secured retailer. The purpose of this paper is to investigate if increment in various combinations and aspects in online payment will in fact improve the customer's perception of the e-retailer and result in completed transactions. In order to investigate this aspect, an experiment was conducted to be able to compare eight independent groups, that each had been exposed to a different security scenario on the online payment website of either a known or unknown retailer. Our results clearly prove that perceived security of the retailer's payment website increases willingness to purchase from the retailer.

Individual adaption to the student´s needs is a recurring main theme in the new Swedish curriculum (Lgr11). The purpose of this qualitative study is to examine how teachers work with individual adjustment for students with reading and writing difficulties. The study was based on five questions;In what way do teachers organize their teaching in the classroom individually for students with reading and writing difficulties?What methods do they use for student´s with reading and writing difficulties?What difficulties do they encounter in their teaching?How do the teachers reason to curriculum goals regarding individual adaptions?How do they think about their own knowledge regarding reading- and writing difficulties and dyslexia?The method for my study was qualitative interviews. Five teachers were interviewed in semi-structured interviews.

This study aims to examine how teachers in elementary school reason about and effectively implements special needs education. A qualitative study was made by interviewing four elementary teachers about their own role in dealing with pupils in difficulty. The material was then analyzed using content analysis. The result section is presented by the study's issue and then been analyzed against the background research. In the analysis it follows that the teachers believe among other things that there is too little time and resources to meet pupils in difficulty, the time and resources in schools is essential when it comes to meet students' needs.

A school is a social area in which children and adults meet each other. The school is were friendship, love and also enmity arise. The process to establish, maintain, split up and end relationships is constantly continuously. A Childs way of creating relationships is complex. Bullying and similar offending treatment occur and has always been a huge problem in school.

Title: Why Great Britain? ? Swedish Encyclopaedias and the Explanatory Perspective of History, Essay in History AbstractIn my essay I describe how Swedish 20th century encyclopaedias interpret the coming about of the British Empire, the overall purpose being to establish a pattern of evolution in terms of historical understanding on the part of the encyclopaedic literature. Firstly, I have tried to determine whether the presentations at all constitute explanatory efforts. In those cases where they do, I have sought to ascertain whether the reasons put forward are to be understood as structural and stable, or as matters of less permanence. I have also tried to link these interpretations to significant ?constructions? of history ? i.

Infection with intestinal parasites can in many cases be the reason for decreased performance or production. The gastro-intestinal nematode, Ostertagia ostertagi, and the lungworm, Dictyocaulus viviparus, are the most pathogenic nematodes of cattle and severe infection can lead to death. They have both a direct lifecycle and on the pasture the parasites spread as freeliving worms. The parasites are mainly a problem for the first season grazers. They have not developed immunity against the parasites and are therefor more sensitive to parasite infections.

In today's society, more and more people traveling with transports such as trains and buses. With this type of travel it often exists waiting at stations that in many cases perceives as negative. Previous research demonstrates that distraction can get people to experience the waiting as less negative. This paper aims to examine how waiting can be affected by distraction, and if it is possible to use a second type of waiting as a distraction. The authors have chosen to focus on travelers who are waiting.

KSL Trading Inc is a trading company in the Jönkoping area that distributesmaterial for the furniture and interior design industry.The purpose of this report is to analyze the existing material flow andwarehouse layout as well as to identify the issues there are today at KSL?swarehouse for board material. When we identified what kind of problems thatexisted we were able to design a new plan for the material flow and storagepossibilities. The problems we found where:? There is no well-organised warehouse layout? There are no routines to keep the warehouse clean and in order? There is no formed plan how to handle materialTo solve these problems we have used different methods like interviews,observations, calculations and literature studies.