Mast cells have for a long time been known to accumulate around tumors (Maltby et al., 2009). Studies show that they may be important and sometimes essential in tumor angiogenesis, tumor growth and metastasis of tumors (Soucek, et al., 2007; Xiang et al., 2010). In an expression array study (Wensman et al, submitted manuscript) performed on mouse mast cells exposed to tumor conditioned medium, the gene 4-1BB was among the most up-regulated genes compared to control medium. 4-1BB codes for a membrane receptor protein of the tumor necrosis factor superfamily and has been shown to be important in T cell regulation in tumor diseases. This study was performed to investigate if human mast cells up-regulate 4-1BB when they get exposed to tumor conditioned medium.

Bakgrund: Stroke är den tredje största dödsorsaken i Sverige och den vanligaste anledningen till funktionsnedsättning. Intresset för kroppsmedvetna behandlingsmetoder inom strokerehabilitering har ökat. Basal Kroppskännedom (BK) är en behandlingsmetod där fokus ligger på kroppsmedvetenhet, rörelsebeteende och grundläggande rörelseförmåga för att därigenom återställa kroppslig och själslig balans. Syfte: Syftet med litteraturstudien var att studera beskrivna behandlingsmetoder med inriktning på kroppsmedvetenhet inom strokerehabilitering. Ett annat syfte var att i en kvalitativ studie undersöka om gruppbehandling i BK ger effekter som är möjliga att se ur ett anhörigperspektiv.Metod: För litteraturstudien gjordes sökningar i PubMed, AMED och CINAHL med sökorden stroke, physiotherapy, intervention, body awareness, tai chi, yoga, gigong, alexanderteknik, feldenkrais.

The purpose of this essay is to examine Swedish HR-managers who have either received, or been nominated for, the award ?HR-manager of the Year?. We investigate the managers? personalities, how they think about their own role and HR?s function in the organization, all in an environment that can be characterized by some skepticism towards HR. We find the HR-managers to be ?winners?; strong individuals that are confident, communicative, and driven.

This study aimed to describe children?s experience of living with overweight or obesity, by using a literature-review. The study includes eleven articles, data is from children between ages 5-15 year. The result occurring were in the areas; Quality of life and self-esteem, Social company, Body concept and weight reduction and Psychological unhealth. BMI above what is recommended gives a negative influence on quality of live and self-esteem.

Motivationsskapande åtgärder är avgörande för de anställdas nöjdhet inom organisationen. Vad som motiverar de anställda varierar från individ till individ. Vårt resultat visar att det existerar ett samband mellan de anställdas nöjdhet och hur väl organisationens strategi, struktur, utvärderingar och belöningar stämmer överens med olika karriärinriktningar och drivkrafter. Studien visar även att de anställdas nöjdhet påverkar kundernas nöjdhet med servicen..

Today's technology offers a variety of opportunities to interact with the interactive systems. Human-Computer Interaction in the last decade is the area of research that has contributed the most to this development. But how is this interaction perceived? The user experience is something that is formed by the interaction between human and the computer interactive systems. The objective of this thesis is to investigate how the user experience differs depending on how one interacts with a game.

Most studies regarding wolf (Canis lupus) predation on moose (Alces alces) have focused on the total annual consumption of moose within a wolf territory but few have tried to describe the spatial impact of wolf predation on a local scale. In this study I have analyzed wolf movement data, wolf predation, moose hunting statistics and moose hunter observations to investigate how wolf predation affects the human harvest of moose in Scandinavia. Since wolves prey on mostly juvenile moose during summer, analysis of their summer movement patterns is crucial to understand its impact on the human harvest later during autumn. In this study both reproducing (n = 45) and non-reproducing wolves (n = 12) reduced their movement range during summer to 66% and 67% of their annual movement range, respectively. Reproducing wolves increased their movement range from early to late summer while non reproducing wolves did not.

Small business enterprises have escalated in Sweden during the last decade. However, new established companies are struggling to maintain their selves during the startup process and according to a survey from Tillväxtanalys, only 68 % of startup companies from 2008 were still active three years later. One of the main reasons is lack of capital and the most common approach to finance companies is to apply for a bank loan. In other words, commercial banks are of great importance for new businesses. Although, the problem arises when there is no previous history from the new businesses that the bank could base its credit assessment on.

The purpose of this thesis is to examine if the school's democracy project is successful. The objective is examined in relation to two specific questions. The first question is whether students, after completing their studies in civics A, understand the relationship between the concepts of human rights and democracy. The second is if the students understood the concepts of practical significance and impact on society and the individual. Variation theory comes from the phenomenographic theories and is central to this work. The approach to learning, in this essay, is a change in how a person experiences, understands or perceives a phenomenon. Variation theory focuses on a learning object and contextualization sees as crucial to how the individual perceives the object.The study is based on a quantitative research method in the form of a survey at a secondary school. A number of students may respond to valuation questions about how they perceive democracy and human rights in practical situations. The results are related to curriculum goals.The results of the study is not positive in relation to curriculum objectives, where many students respond negatively to questions..

Lot?s of reasons are showing that outdoor life has a positive influence on the general publics health and studies are confirming this theory. On the other hand there are a few amount of Swedish science project?s regarding outdoor life. The aim of this study was to examine how people feel that their health influences by outdoor life.

Background: The purpose of this study was to explore the reasons that motivate women to seek cosmetic breast augmentation surgery, to examine their self-concept and how they relate to their breasts.Methods: Ten female postoperative participants who have undergone an aesthetic breast augmentation surgery on private clinics were interviewed using an unstructured interview format. Self-report questionnaire was used as a complement to the interview. The purpose of this was to examine women's self-concept. Six female postoperative participants who have undergone a breast augmentation surgery on public clinic and had medically confirmed defect also completed the measures.Results: The results of the interview analysis showed that some participants experienced positive physical and psychological outcomes of surgery and some did not. Several main themes were identified relating to the initial reasons for performing surgery.

In this essay, I want to achieve an accessible and applicable entrance to Alexander Technique as a method for learning to use the body in such a way as to allow emotional expression in music. It is necessary to see the real need of Alexander Technique for the active musician, and therefore important components of music-making will be presented. These components are presented from an Alexander-perspective in order to produce a clear picture of the method of application.The prerequisite for emotional expression in music is musicians and music listeners with the ability to generate, and respond after emotional impressions. Alexander Technique provides an approach to make it easier for musicians, especially guitarists, to express emotions in a performance situation.After years of practice and obtaining musical knowledge and practical skills at the instrument, it is common that muscle tension and ingrained patterns contribute to limited expression. Muscle tensions arising from pressured situations such as auditions, competitions and concerts.

We have made a litterature study about pain in animals. In this studie we have brought up areas like sign of pains in animals, pain relief and the care perspective. Pain is perceived when body tissue is damaged or nearly damaged by stimuli. Nociceptors, which are receptors placed at nerve endings, responds to a provocation of pain and transmit an impulse along the nerve to the brain via the spinal cord. Pain is urgent or chronic, and can be divided into nociceptive pain (somatic pain and visceral pain) and neuropathic pain. Different pain mechanisms can arise, such as referred pain, which is when signals of pain are referred to other parts of the body.

This study focuses on the development of methods for sexual determination of human skeletal remains, mainly between the years 1981 to 2007. By comparing an older analysis from 1983 (Persson and Persson) with my own on the same material, a difference of 40% was shown, which indicates that the methods has changed through time, and that these should not be used for newer conclusions about a population if the method is not throughoutly described.The main cause of the difference was identified as a change in the reliability of the sexual indicators, rather than a total change of method. Any general tendencies did not show, it is however considered that the pelvic bones are able to make a better conformity between the analyses as opposed to using the cranium..

This paper discusses an osteological- and archeological analysis of a cairn from the Bronze Age on Gotland. The osteological material consists of both burnt and and unburnt bones from both human and animal. The objective of this paper is to shed light on the individuals who were buried in the cairn. It is also to generate information about continuity in its use and patterns of distribution of the bones and grave-goods in the cairn. The osteological analysis show that a minimum of five human individuals is present in the osteological material.