Fibroblast growth factors are signaling peptides that controls important cellular processes such as proliferation, differentiation, migration, adhesion and survival. Through binding to different types of receptors on the cell surface, these peptides can have different effect on the target cell. Which effect that is achieved depends on many factors. Thus, each of the 24 known FGFs different biological responses. The FGF receptors (FGFR 1-4) initiates different intracellular pathways which in turn leads to different biological responses.

This master thesis was a subtask of a project called EMIR-1. The goal with the thesis was tobuild a system for particulate mass measurements in one of the engine tesT cells at KTH. Theparticulate mass measurements are planned to be measured with a TEOM.The exhaust gases must first be diluted with air before the sample is sent to the TEOM.Therefore an ejector diluter for this matter also was designed and evaluated in the thesis.Emissions measurements have been done both with and without dilution to determine thedilution ratio. Tests have been done for different speeds and loads.Problems with stability of the dilution ratio have been an issue throughout the process andpressure pulsations in the exhaust pipe are believed to be the cause. More tests have to be done tomake sure that this is the problem.One idea is to make the inner diameter of the diluter nozzle smaller and see if it changes thedilution ratio stability.

The dog has often served as a model animal for humans in scientific studies. This is due to the fact that dogs are susceptible to a wide range of diseases which also affect humans. One example is cancer, a condition that affects dogs as well as owners. Neoplastic diseases account for 18-23 % of all deaths in dogs (Bonnet et al., 2005 and Jagielski et al., 2002). Mammary tumor, or tumor of the breast, is the most common tumor form in intact dogs and women (Im et al., 2013). Mammary tumors originate in the udder, and are classified according to their histological characteristics.

The vertical electronic excitation energies for the narrow-bandgap polymers LBPF, EP37 and EP62 have been calculated using Density Functional Theory (DFT). Also the vertical excitation energies for the acceptor unit of LBPF have been calculated using the Hartree-Fock (HF), DFT and Coupled Cluster (CC) methods. The calculations cover the visible and infrared wave length region and two strong transitions are obtained, one corresponding to the pi to pi* transition and one corresponding to the pi to Acceptor transition. The excitation energies obtained from DFT are below the corresponding experimental results and attempts have therefore been made to perform bench-marking calculations using a hierarchy of CC methods..

This thesis is made by Carl Persson and Alejandro Saavedra for Gryaab. Gryaab is Gothenburg?s water processing plant and produces about 60 GWh biogas annually with a flow around 1150 Nm3/h. Gryaab wants to research their possibilities to become independent with electrical energy and the possibilities to enrich, upgrade biogas. The use of methane rich gases like biogas and natural gas is today low in Sweden compared to major parts of the world.

Proteins are vital to all cells in the body. They consist of long chains of amino acids. To be able to study the amino acid composition of a protein it is necessary to hydrolyse it, followed by separation and quantification. When the protein is hydrolysed, in this case ß-lactoglobulin, the protein is divided into individual amino acids. The method that traditionally has been used to hydrolyse proteins takes 24-72 hours to complete.

A design methodology to mitigate timing problems due to long wire delays is proposed. The timing problems are taking care of at architecture level instead of layout level in this design method so that no change is needed when the whole design goes to backend design. Hence design iterations are avoided by using this design methodology. The proposed design method is based on STARI architecture, and a novel initialization mechanism is proposed in this paper. Low frequency global clock is used to synchronize the communication and PLLs are used to provide high frequency working clocks.

Proteins are vital to all cells in the body. They consist of long chains of amino acids. To be able to study the amino acid composition of a protein it is necessary to hydrolyse it, followed by separation and quantification. When the protein is hydrolysed, in this case ß-lactoglobulin, the protein is divided into individual amino acids. The method that traditionally has been used to hydrolyse proteins takes 24-72 hours to complete.

This is a graduation project in Innovation Management, which seeks to enlighten new theories within the major subject ? the multi?faceted innovation process.The reader is hereby invited to an insight in the more complex perspectives of these types of theories than what has previously been explained in simplified ways.We have conducted research on a company within the cleantech market; Cellkraft AB. The company develops and produces fuel cells amongst other products, which have emerged during their research and development in the fuel cell technology. Cellkraft works in a high?tech frontline market where innovation is key.

Hundreds of thousands of piglets are castrated without anesthesia in Sweden every year so that we may be guaranteed meat without boar odor. The smell appears while cooking meat of boar and is described as urine- and sweat-like. High levels of androstenone and skatole are considered the main factors behind boar odor. Skatole is a metabolite of the amino acid tryptophan, which is formed in the colon of all pigs. Androstenone is a steroid hormone that is released from the Leydig cells in the testes of boars.

The purpose of this review was to study the cow eye physiology, focusing on how it registers light, and to see how light affects the cow?s milk yield. It has been showed in studies that more hours of light per day (16 hours of light a day) as opposed to about 9-12 hours of light a day, increases milk yield for dairy cows. This review contains suggestions on how this is connected with the physiology of the eye. Vision is an important sense for many mammals, and is used to check out the animals surroundings. Sensor cells in the eyeball help in turning photons from the light into signals to the brain.

Diabetes mellitus is an endocrine disorder affecting a range of different mammals, including dogs, cats, horses and humans. Worldwide, 347 million people have diabetes, and the disease is an increasing burden on the world?s poorest countries. The disease is characterised by chronic hyperglycaemia and afflicted individuals experience increased thirst, polyuria and weight loss, sometimes despite increased appetite. Diabetes mellitus is either insulin dependent or non-insulin dependent.

Background: Cystic fibrosis (CF) is the most common hereditary disease that leads to an early death. Earlier CF was considered as a childhood disease but today the expected age is 50 years. CF affects all the epithelial cells in the body which makes mucus and other body fluids more viscous than normal. The thick mucus leads to among other things respiratory problems and infections of the lungs. Today there is no cure, only medicines that controls the symptoms.Aim: To describe parents experiences living with a child with CF.

Nötcenter Viken is a Swedish nucleus herd for dairy cattle. The goal for the farm is to select suitable mothers for the next top generation of bulls. Today the selection for udder health is based on a pedigree index and phenotype data. The pedigree index is based on the cow?s father and grandfathers breeding values.

This thesis has been performed at the system development company Verendus System AB, together with the home care company Basic Care Unit (BCU).The thesis has consisted of developing a web based informationsystem for BCU in which they can administrate their business. At the time of writing this thesis, BCU was using a windows-application to administrate their activities, which was both costly aswell as resulting in an unnecessary burden. The aim the thesis has thus been to create a platform-independent information system that simplifies and streamlines BCUs work by being user-friendly aswell as imposing some simplifying features.The students has been developing the system by the help of a work method they themselves developed. The method consisted of working in several iterations that each had several milestones. The method resulted in the students knowing easily when each iteration was finished or not.The thesis resulted in a working platform independent prototype.