Background: Chemotherapy and radiation resistance are major causes of failure in cancer treatment. The response to treatment in cancer cells depends on several mechanisms and pathways such as Janus kinases-signal transducers and activators of transcription JAK/STAT pathway. STAT1 was the first described transcription factor in the STAT family. STAT1 is activated by stimulation of signaling proteins such as type II interferon (IFN- ?) and the activated STAT1 translocates from cytoplasm to nucleus.

Today most dosages used in horse medicine are based on studies in adult horses. Since there are differences between adult and neonatal horses with respect to different pharmacological parameters this can cause problems when administring drugs to neonatal foals. Neonatal sepsis is a common cause of morbidity and mortality in foals and aggressive antibiotic treatment is needed immediately when sepsis is suspected. In Sweden the combination of trimethoprim/sulphadiazine and bensylpenicillin is often used as the initial treatment. When administering drugs, interactions can occur between the drugs and endogenous substances.

Canine otitis externa is a common reason for a visit to the vet. Predisposing factors often complicate treatment and may result in a chronic disease progression. All otic preparation for topical use in Fass Vet contain antibiotics, corticosteroids and a fungicide. Sixty cerumen samples from dogs with external otitis, sent to the Department of Bacteriology at SVA, were categorised according to their profile of isolated microorganisms. Staphylococcus intermedius alone or together with Malassezia pachydermatis were the most common organisms found. Fifteen percent of the samples contained M.

AbstractFalu Copper Mine and Sustainable DevelopmentKarl-Markus AnsnaesFalu copper mine was Sweden?s oldest mine industry which lasted for almost a thousand years. Throughout the history its area has been vastly contaminated by sulfur oxide. The contaminations has created the mining area to an environmental risk zone which has the ability to spread out into the Falu River. The river has its connections to the Dal River which is discharging towards its mouth in the Baltic Sea.

Organic material used for biogas production can also undergo other treatments. The emissions and impact from the different treatments are evaluated in this environmental assessment, with a focus on energy and climate. The materials included in the study are organic household waste, slaughterhouse waste and liquid manure. Other than biogas production, the possible treatments for organic household waste and slaughterhouse waste are incineration and composting, and for liquid manure storing and spreading. The analysis is based on data and information from current and relevant literature, and relates to the conditions in the Swedish energy system.

When grains of wheat and rye are conventionally milled, large quantities of bran classified as by-products are left and are mainly used for animal feed. Bran is a complex material composed of the aleurone layer, nucellar epidermis, a seed coat, a fruit coat and a small proportion of the germ and endosperm depending on extraction rate. The bran fraction consists of approximately 40-50 % dietary fibre which can contribute to increase the nutritional quality of human cereal food. It would also be valuable for the food industry to convert by-products as bran to products with higher commercial values. The aim of this thesis was to analyse the content and composition of dietary fibre of heat treated wheat and rye bran according to the Uppsala method with some modifications in order to analyse soluble and insoluble dietary fibre separately. Half of the bran samples were precooked, dried and roasted and the other half dried and roasted (uncooked).

Several diseases increase the risk of thrombosis in dogs and cats, often with a fatal outcome. Currently there are no definite treatment guidelines for the use of thrombolytic and thromboprofylactic agents in veterinary medicine. None of these drugs are approved for dogs and cats in Sweden. Medicines aimed for humans have been used tentatively. This literature study is an investigation of what is currently known about the effects and safety of these pharmacological agents when used for dogs and cats.

Syfte: Sammanställa och granska studier gällande postoperativ behandling vid ruptur av ligament patella. Detta för att beskriva effekt och kvalitet på studier om postoperativ behandling.Metod: En beskrivande litteraturstudie valdes som design, med sökorden: patellar ligament, patellar tendon, rupture, knee injuries, surgery. Av totalt 1240 träffar valdes 13 relevanta artiklar publicerade mellan 1999-2013 efter sökningar i databaserna PubMed, PEDro, COCHRANE, SCOPUS, CINAHL, SPORTDiscus och AMED. Artiklarna kvalitetsgranskades enligt PEDro scale.Resultat: Två postoperativa behandlingar beskrevs, tidig och sen mobilisering. Antingen placeras knäleden i ett stabiliserande knäskydd som till en början låser knäleden i full extension eller så påbörjas tidig mobilisering av den opererade knäleden.

The purpose of this study has been to make an inventory of combustible waste in the region around Norrköping and to investigate the composition of domestic waste, industrial waste and two different types of sludge. The work was performed at the request of Norrköping Miljö & Energi, due to the planning of an incineration plant. The inventory of the waste was performed through inspection of environmental impact reports, from waste disposal plants in a number of local government areas in the region. The quantities were also compared to another inventory, carried out in a different way. The characterisation of the wastes was compared to the fuel specification determined by Norrköping Miljö & Energi.

In this study we have examined in which way the horse is used in Equine Assisted Therapy, and what effects the treatment staff experience and describes that the interaction with horses has on girls who self-harms. Our Empirical data was collected through qualitative methods such as interviews, participant observation and informal interviews with a total of six different informants, from five different activities with Equine Assisted Therapy for girls who self-harms. In the analysis we have assumed symbolic interactionism, a theory focusing on the human as a social being, where the self-image alters in the social interaction with other human beings. We interwove this theory with the Biophilia hypothesis, an explanatory model concerning human?s relationship to animals and nature.The conclusions we have found in the results are:Equine Assisted Therapy is a complementary treatment comprises both horseback riding and exercises which is not based on the horsebackEquine Assisted Therapy almost always involves three parts, the therapist, the client and the horse.

Världshälsoorganisationens (WHO) checklista för säker kirurgi utvecklades för att minska risken för kirurgiska komplikationer och dödsfall i samband med kirurgi. Kommunikationen i operationssalen behöver förbättras mellan alla personalkategorier så att säkerhetsåtgärder blir konsekventa och rätt utförda. Målet med sjukvården är att främja en hög patientsäkerhet för att minimera andelen vårdrelaterade skador. Trots att WHO´s checklista visat positiva resultat finns indikationer på att följsamheten minskar samt att den möts av motstånd från personalen. Syftet med studien var att belysa operationssjuksköterskans upplevelse vid användningen av WHO´s checklista.

Drinking water is produced from raw water and is either from groundwater or surface water. This thesis aims to find out if the cleaning process of raw water is sufficiently effective. This is important because consumers are otherwise at risk of waterborne infection caused by pathogens. There are three groups of pathogens; bacteria, virus and parasite. These have different characteristics which mean that they require different water treatment to be separated.

Drinking water is produced from raw water and is either from groundwater or surface water. This thesis aims to find out if the cleaning process of raw water is sufficiently effective. This is important because consumers are otherwise at risk of waterborne infection caused by pathogens. There are three groups of pathogens; bacteria, virus and parasite. These have different characteristics which mean that they require different water treatment to be separated.

The worsening of psychical health issues among young people has widely been discussed over the last few years. Research shows for example that 9% of girls at the age of 16-24 reported anxiety problems in 1989 while 16 years later, in 2005, the same number was 30%. The purpose of this essay was to study and analyze psychiatrists', psychologists' and counselors' view on the resilience and risk factors for youth depression (age 16-24). Beside this, our aim was to study their view on the influence of family environment on treatment and recovery. Data were collected with qualitative interviews with eight informants within the psychiatric care.

Idag riktas allt mer fokus i samhällsdebatten och i politiken på personer medallvarlig psykisk sjukdom. Man debatterar dels hur samhället skall kunna tillhandahålla enhögkvalitativ vård och ett bra omhändertagande, men också ur ett samhällsekonomisktperspektiv. Den psykiatriska slutenvårdens kostnader är höga och debatten handlar ofta omhur dessa kostnader skall kunna reduceras.Denna studie vill titta närmare på om metoden Case management enligtAssertive Community Treatment (ACT) kan bidra till att den psykiatriskaslutenvårdskonsumtionen minskar för personer med allvarlig psykisk sjukdom. För attgranska detta har intervjuer med fyra brukare använts där frågeställningen var fokuserad påderas subjektiva upplevelser av att erhålla Case management enligt ACT under en period avtre år. Vidare granskades skattningar enligt Kvalitetsstjärnan som utförts under en tre årsperiod.