Clopidogrel is an antiplatelet substance that prevents blood coagulation in the arteries. It is an inactive pro drug that becomes activated after first-pass metabolism by the liver. The active metabolite of clopidogrel is 2-oxoclopidogrel, which is unstable therefore pharmacokinetic data is obtained by measuring the inactive metabolite clopidogrel acid in plasma. Clopidogrel is taken orally in tablet form. The aim of this project was to develop a LC-MS/MS method for quantification of clopidogrel and its metabolite in plasma. The method has been developed by optimizing the sample preparation.

A richer language when painting before speaking? ? What is a rich language and can painting stimulate towards a richer language?In this work I seek to answer two questions. What may a ?richer? language mean and does it become richer when the informants, as a preparation, paint what they are going to talk about in front of the class, than when they do not paint? This I try to do by studying earlyer research about how to measure the richness in languages and by analysing video recordings of speeches when the students in an sfi-class (Swedish for foreigners) painted or did not paint before the speech, and by analysing the richness in their language. The result is my own definition of what rich language is in this context, and a conclusion that painting stimulates the students to use more words and to use specific words that they need to bring the audience their message..

This is a study made because I would like to see how much money can be saved when reduced soil preparations is used. This is a case study, the farm is located in the north vest part of Skåne, Sweden. I have calculated with four different soilpreparation methods. Alternative 1: Conventional soil preparation, the way the farm is managed today. Alternative 2: Ploughing on depth of 12 centimeters, with a ridge packer followed with sowing. Alternative 3: Eco-tillage Alternative 4: Direct drilling The results of my study showes that Alternative 2 is the most profitable. Alternative 4 is very good if you see to dieselexpenses and hours of work, but the yield is far to low. If the numbers are further analized, it showes that in spring barley the differense between Alternative 2 and Alternative 4 is at a minimum. So if there is lack of time for one reason or another, this might be an alternative in spring barley. The differense in how the farm is managed today and the most profitable alternative in the study, Alternative 2 showes that it can be saved up to 60 940 SEK..

My intention with this study is to evaluate, as a singer and a voice teacher, a number of routines for daily vocal practice through practical application. Seven different routines are presented, five of them originating from interviews with Swedish vocal teachers and singers and two chosen from literature. These routines are then tried out and evaluated. Using the results of these evaluations as a basis, I make an attempt at formulating my own personal practice routine, optimal for my own needs. I will also try to address motivational issues related to practice with hints acquired through the interviews.

Today it is common to spray against most weeds by using very expensive weed-killers. The goal for every farmer is to have as low costs as possible for their use of machines and weed-killers. Therefore it is in everyones interest to find other methods to fight the weeds. Finding a way to reduce the rise and growth of weeds already at the preparation of the soil would lower the number of laps over the field and also decrease the amount of weed-killing dose. Tests show that by harrow in the dark it is possible to reduce the population of weeds with up to 60%, but the normal reduction would be about 20-30%. To verify the results above we made tests by using two different methods of preparing the soil. We tested ploughing and harrowing in daylight and during night. Later we checked the number of different weeds in areas prepared in daylight and during night. By studying the results from the different methods used we found a considerable reduction of some kinds of weeds in areas prepared during night..

During Spring semester 2011, Linda Engstrom and Malin Heder performed ?Golden Ratio?, a thesis which included 22.5 hp. The thesis followed the syllabus for the Degree Project for degree of Bachelor of Science in Innovation and Design Engineering (MSGC12) which was a unit in the Innovation and Design Engineering program within the Faculty of Technology and Science at Karlstad University.The client was Crem International AB, a company located in Åmotfors that develops the design, manufactures and markets coffee machines. The supervisor at the company has been Peter Larsson and supervisor at Karlstad University has been Monica Jakobsson. Examiner for the thesis has been Professor Fredrik Thuvander at the Faculty of Technology and Science at Karlstad University.Crem International AB controls a patent, representing a new technology to streamline and minimize use of energy during the coffee preparation and results in a good coffee quality.

The Regional Forestry Board in Värmland- Örebro needs increased knowledge on silviculture in broad- leaved forests. This thesis is an inventory of naturally regenerated broad leaved forests, and the results from the inventory have been compared with The Regional Forestry Board?s demands on regeneration results. The result of this inventory was that the regenerated sites were suitable for broad leaved trees, but only half the number of the stands fulfilled the demands of regeneration results of The Regional Forestry Board, mainly because of gaps in the stands. The gaps in the stands were mainly caused by lack of soil preparation and seed trees..

Part 1 of 2  ? Lean philosophy ? five steps to get the workplace in order?Part one deals with the theory of what Lean and 5S are.Lean is a long-term approach that involves a quest to become the best on the market by increasing employee engagement, eliminate waste and focus on the right things.5S is a method of order in a system. Businesses around the world are using these 5S which stands for sort, straighten, shine, standardize and sustain. Part 2 of 2 ? Lean philosophy ? five steps to get the workplace in order?Part 2 deals with the practical about 5S and a short summery about the company Wibax AB where the degree thesis took place.Wibax has a a project which involves using 5S in practice and create order in the in preparation lab and in the control room.By finding a solution to this mess reduces the time that was previously spent on searching equipment. Instead of search, the workers can do the real work..

During Spring semester 2011, Linda Engstrom and Malin Heder performed ?Golden Ratio?, a thesis which included 22.5 hp. The thesis followed the syllabus for the Degree Project for degree of Bachelor of Science in Innovation and Design Engineering (MSGC12) which was a unit in the Innovation and Design Engineering program within the Faculty of Technology and Science at Karlstad University.The client was Crem International AB, a company located in Åmotfors that develops the design, manufactures and markets coffee machines. The supervisor at the company has been Peter Larsson and supervisor at Karlstad University has been Monica Jakobsson. Examiner for the thesis has been Professor Fredrik Thuvander at the Faculty of Technology and Science at Karlstad University.Crem International AB controls a patent, representing a new technology to streamline and minimize use of energy during the coffee preparation and results in a good coffee quality.

During Spring semester 2011, Linda Engstrom and Malin Heder performed ?Golden Ratio?, a thesis which included 22.5 hp. The thesis followed the syllabus for the Degree Project for degree of Bachelor of Science in Innovation and Design Engineering (MSGC12) which was a unit in the Innovation and Design Engineering program within the Faculty of Technology and Science at Karlstad University.The client was Crem International AB, a company located in Åmotfors that develops the design, manufactures and markets coffee machines. The supervisor at the company has been Peter Larsson and supervisor at Karlstad University has been Monica Jakobsson. Examiner for the thesis has been Professor Fredrik Thuvander at the Faculty of Technology and Science at Karlstad University.Crem International AB controls a patent, representing a new technology to streamline and minimize use of energy during the coffee preparation and results in a good coffee quality.

During Spring semester 2011, Linda Engstrom and Malin Heder performed ?Golden Ratio?, a thesis which included 22.5 hp. The thesis followed the syllabus for the Degree Project for degree of Bachelor of Science in Innovation and Design Engineering (MSGC12) which was a unit in the Innovation and Design Engineering program within the Faculty of Technology and Science at Karlstad University.The client was Crem International AB, a company located in Åmotfors that develops the design, manufactures and markets coffee machines. The supervisor at the company has been Peter Larsson and supervisor at Karlstad University has been Monica Jakobsson. Examiner for the thesis has been Professor Fredrik Thuvander at the Faculty of Technology and Science at Karlstad University.Crem International AB controls a patent, representing a new technology to streamline and minimize use of energy during the coffee preparation and results in a good coffee quality.

The aim of this thesis is to analyse and if possible improve the communication, mainly seen from a pedagogical perspective, between the IT company (Nostratic) and their clients in a first meeting. The analysis covers the preparation part, communication during the meetings, the technical terminology used during the meetings as well as the follow up of the meetings. Due to the lack of research within this area and the lack of personal experience on my part, the conducted study has been explorative with the use of qualitative methods. Although my first aim was to put emphisis on the pedagogical part of the communication, I found while conducting the study that there were other areas of higher importance to analyse in order to improve the customer meetings. Unfortunately the company went bankrupt in the middle of my study which resulted in me not beeing able to try out the potential improvements.

The combat mission is an extreme situation with high demands of the soldier. Killing might very well be necessary. Before a mission a soldier can experience stress due to these factors. The purpose of this paper is to find methods to handle stress due to an upcoming combat mission and to the prospect of having to kill. The main questions of this essay: -How can certain parts of the physiological psychology improve a soldiers ability to perform a mission? ? Is the Swedish soldier mentally prepared to kill? The theory for this essay has been described using litteratur by experts within the field, and the results thereafter discussed.

The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

Hundreds of thousands of piglets are castrated without anesthesia in Sweden every year so that we may be guaranteed meat without boar odor. The smell appears while cooking meat of boar and is described as urine- and sweat-like. High levels of androstenone and skatole are considered the main factors behind boar odor. Skatole is a metabolite of the amino acid tryptophan, which is formed in the colon of all pigs. Androstenone is a steroid hormone that is released from the Leydig cells in the testes of boars.